New combo aims to tame immunotherapy side effects in advanced melanoma
NCT ID NCT05428007
First seen Jan 11, 2026 · Last updated May 22, 2026 · Updated 22 times
Summary
This study tests whether adding the arthritis drug sarilumab to a three-drug immunotherapy cocktail can make treatment safer and more effective for people with advanced (stage III or IV) melanoma that cannot be removed by surgery. About 105 participants will receive the combination. The goal is to reduce severe immune-related side effects while still controlling the cancer.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Dana Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
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NYU Langone Health
RECRUITINGNew York, New York, 10016, United States
Contact Phone: •••-•••-••••
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The Angeles Clinic at Cedars Sinai
RECRUITINGLos Angeles, California, 90025, United States
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Conditions
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