Type 1 diabetes mellitus

This phase 3 trial is testing an experimental mRNA vaccine called mRNA-1345 to see if it can protect against respiratory syncytial virus (RSV) in adults who are at high risk of severe illness. The study includes two groups: adults aged 18 to 59 with chronic health conditions like…

This study tested an extra dose of the HIPRA COVID-19 vaccine in 241 adults with conditions like HIV, kidney disease, or autoimmune disorders that weaken the immune system. The goal was to see if the booster raises antibody levels against virus variants and remains safe. Research…

This study tested a smart cap that attaches to insulin pens to help people with type 1 diabetes track their injections and glucose data. 42 adults used the device or a blinded version for comparison. The goal was to see if it reduces time spent with high blood sugar and improves …

Researchers are testing whether continuous glucose monitoring, alone or combined with a family behavioral program, helps children under 8 with type 1 diabetes keep their blood sugar in a healthy range. The trial compares these approaches to standard home blood glucose monitoring.…

Researchers at Nantes University Hospital are testing a computer model that describes how glucose and insulin interact in people with type 1 diabetes. The model aims to help doctors choose insulin pump settings, including basal rate, insulin sensitivity, and carbohydrate ratios. …

This completed Phase 1 study tested a new fast-acting insulin called NNC0471-0119 in 43 adults with type 1 diabetes who use an insulin pump. The goal was to see how quickly the insulin enters the bloodstream, how long it works, and how safe it is compared to a standard insulin (i…

This completed trial tested whether a faster-acting insulin (Lyumjev) used with a special conversion factor in an automated insulin pump (Control-IQ) could improve blood sugar control in 11 adolescents with type 1 diabetes. Participants were randomly assigned to use Lyumjev with …

This study tests whether adding empagliflozin or semaglutide to insulin can improve blood sugar control in overweight or obese adults with type 1 diabetes. About 105 participants will take one of the two drugs or a placebo for 3 months. The goal is to see if these drugs help lowe…

This study is checking how safe and effective an updated insulin pump system (Control-IQ 1.5) is for children ages 2 to 6 with type 1 diabetes. About 144 kids will use the pump for a year while researchers track dangerous low blood sugar events and diabetic ketoacidosis. The goal…

This study tests a new insulin infusion set designed to last up to 7 days for people with type 1 diabetes. Twenty adults currently using a Tandem insulin pump and Dexcom CGM will try the SteadiSet at home. The goal is to see if the set can survive a full week without causing high…

This trial tests whether using the Accu-Chek Aviva Expert, a bolus calculator, helps children and adolescents with type 1 diabetes achieve better blood sugar control and a better quality of life. Participants, who already count carbohydrates and use multiple daily insulin injecti…

This study tested an experimental drug called BMF-219 in people with type 1 diabetes to see if it could help their bodies produce more insulin. The trial was stopped early, but researchers planned to compare insulin levels between those who got the drug and those who got a placeb…

Many adults with type 1 diabetes don't get enough sleep, which can make blood sugar harder to control. This trial tests a 12-week program called Sleep-Opt that uses wearable sleep trackers, phone coaching, and educational materials to improve sleep habits. Researchers will measur…

This trial tests whether a daily 10-gram dose of sea buckthorn extract, taken for 12 weeks, can improve blood sugar control and immune cell balance in adults with type 1 diabetes. Type 1 diabetes is an autoimmune condition where the body attacks insulin-producing cells. The study…

This study compares two insulin pump systems in adults with type 1 diabetes to see which better controls blood sugar after eating a high-fat meal like pizza. The newer closed-loop pump automatically gives small insulin corrections every 5 minutes, while the older open-loop pump a…

This trial tests whether the type of bedtime snack affects overnight blood sugar levels in children and adolescents with type 1 diabetes who use multiple daily insulin injections. Participants will eat four different snacks—carbohydrate alone, with protein, with fat, or with fibe…

This trial tests whether virtual cooking classes, held twice a month for three months, can help teenagers with type 1 diabetes improve their blood sugar control and learn healthier eating habits. Participants, aged 12 to 17 with a BMI at or above the 85th percentile, will either …

This study tests a telehealth program called REAL-T, designed to help young adults with type 1 diabetes fit diabetes care into their daily habits and routines. Participants receive about 12 hours of virtual coaching from an occupational therapist over six months. The study compar…

This study compares a new diabetes-specific nutritional formula to an existing one in 103 adults with type 1 diabetes, type 2 diabetes, or prediabetes who are at risk for malnutrition. The goal is to see if the new formula is as good as the current one at improving nutrition, mea…

This trial tests a digital health program designed to help young adults with type 1 diabetes improve their blood sugar control. Participants use the SweetGoals app to set and track behavioral goals, and some also receive financial incentives for meeting those goals or access to w…

This trial tests a smart insulin pump algorithm designed to automatically adjust insulin delivery during the night to keep blood sugar levels in a safe range. The algorithm predicts when blood sugar might drop too low and pauses insulin, and when it might rise too high, it gives …

This study tests whether a mobile app can help people with type 1 diabetes adjust their insulin doses better than standard care. About 50 participants over age 15 will use the app or receive usual care for 3 months. The main goal is to see if the app improves blood sugar control,…

This trial is testing an investigational drug called OPT101 in adults with type 1 diabetes. The goal is to see if it is safe and how it affects the immune system. Participants will receive multiple doses of the drug, and researchers will monitor for side effects and measure drug …

This trial tests whether a smart insulin pen called DIA:CONN P8 can help people with type 1, type 2, or pancreatogenic diabetes better control their blood sugar. Participants use the pen for 12 weeks, and the pen automatically calculates bolus insulin doses based on meal informat…

This trial tests whether a specially designed mealtime insulin, HDV-insulin lispro, can reduce nighttime low blood sugar (hypoglycemia) in adults with type 1 diabetes. Participants will use continuous glucose monitors and work with doctors to adjust doses. One group receives the …

This study tests whether an advanced hybrid closed loop insulin pump (MiniMed 780G) can improve blood sugar control, quality of life, thinking skills, and physical abilities in people over 60 with type 1 diabetes. Participants are randomly assigned to either continue their usual …

This study tests whether treating low blood sugar (hypoglycemia) at a slightly lower threshold of 65 mg/dL, instead of the standard 70 mg/dL, can prevent rebound high blood sugar in children with type 1 diabetes. Each child undergoes both approaches in a crossover design, receivi…

This study tests how different amounts of dietary carbohydrates affect insulin needs and blood sugar control in adults with type 1 diabetes. Participants are randomly assigned to one of three diets: a traditional diet with 50-60% of calories from carbs, a moderately low-carb diet…

This study tests whether a peer coaching program delivered by phone and text can help adolescents and young adults (ages 16–22) with chronic conditions like sickle cell disease, diabetes, or cystic fibrosis improve their self-management skills. Participants are paired with a trai…

This study tests a new smartphone-based system that automatically delivers insulin for people with type 1 diabetes. Six adults who already use insulin pumps will try the system for a short time under close supervision. The goal is to see if the technology works safely and reliabl…

This study tests whether a low-carbohydrate diet (under 75 grams per day) can help adults with type 1 diabetes preserve their remaining insulin production. The idea is that the diet might calm the immune attack on insulin-making cells. Participants will follow the diet for a peri…

This study tests a four-week virtual program designed to help teens aged 12-21 with type 1 diabetes use technology like insulin pumps and continuous glucose monitors. Participants complete surveys and interviews about their diabetes management and technology use. The goal is to u…

This study tracks 300 adults with type 1 diabetes who use the Omnipod 5, an automated insulin delivery system, as part of their routine care. Researchers will compare blood sugar control—measured by time in target range and HbA1c levels—before starting the system and at 6, 12, an…

This study tests whether using a continuous glucose monitor (CGM) — a small sensor that tracks blood sugar levels in real time — helps teens and young adults (ages 14 to under 25) with type 1 diabetes improve their blood sugar control compared to standard fingerstick testing. Par…

This study tests whether regular video or phone calls with a nurse (tele-nursing) can help teenagers with type 1 diabetes improve their blood sugar control, feel more confident managing their condition, and reduce anxiety. Participants aged 12–18 receive diabetes education both i…

This study tests a software upgrade for an automated insulin pump system (Control-IQ) in adults with type 1 diabetes. The upgrade adds an adaptive biobehavioral control module that learns from the user's patterns to improve blood sugar management. Participants use the standard sy…

This completed trial tested whether daily omega-3 fish oil supplements can help maintain healthy blood vessels in the eyes of adults with type 1 diabetes. 82 participants took either a 1000 mg omega-3 capsule or a placebo for the study, with regular eye exams to monitor retinal c…

This study tests a family-based behavioral program for youth aged 6-17 with type 1 diabetes who are overweight or obese, along with an overweight parent. The program focuses on healthy meal planning, food literacy, and family habits to improve weight and diabetes control. Twenty …

This study investigates whether drinking galactose before cycling can prevent low blood sugar (hypoglycemia) in people with type 1 diabetes. Fourteen participants will try four different drinks—dextrose, galactose, lactose, or a sweetened placebo—on separate days, then cycle for …

This study tested an updated version of the Control-IQ system, which automatically adjusts insulin delivery for people with type 1 diabetes. Sixty-six adults and adolescents used the new software along with a continuous glucose monitor for several weeks. The main goal was to see …

This study tested whether taking two doses of sodium bicarbonate (baking soda) over 24 hours could reduce uric acid crystals in the urine of adults with type 1 diabetes. Uric acid crystals can harm the kidneys, so lowering them might help prevent diabetic kidney disease. The tria…

This study tested whether transplanting insulin-producing islet cells, along with immune-suppressing drugs, could safely prevent severe low blood sugar episodes in people with type 1 diabetes who don't feel warning signs. Ten participants received the transplant and were monitore…

This study tested whether adding a smartphone app with short videos on mental health, diet, exercise, and insulin adjustment to standard care could improve blood sugar control and birth weight in pregnant women with diabetes. Over 600 women participated. The goal was to see if th…

This study tested whether an educational mobile game could help children aged 7 to 14 with type 1 diabetes better manage their blood sugar. 76 children played the game alongside their usual care. Researchers measured changes in HbA1c (a long-term blood sugar marker) and how satis…

This study tested a new closed-loop system that automatically delivers both insulin and pramlintide to manage blood sugar in 33 adults with type 1 diabetes. Pramlintide slows digestion to prevent blood sugar spikes after meals. The system was compared to insulin alone. Researcher…

This study tested a new fully-closed insulin delivery system that automatically adjusts insulin based on activity and missed meals, compared to a standard hybrid system. 29 adults with type 1 diabetes used both systems to see which kept blood sugar in a healthy range more often. …

This study tested whether adding a smart, AI-powered insulin boost before meals could improve blood sugar control in adults with type 1 diabetes. Nineteen participants used either a standard automated insulin system or the same system with the AI boost during hotel stays and at h…

This study tested whether verapamil, a drug usually used for high blood pressure, can help preserve insulin-making cells in adults newly diagnosed with type 1 diabetes. 136 participants received either verapamil or a placebo for 12 months. The main goal was to see if verapamil co…

This study tested whether oat flakes containing β-glucan, a type of fiber, could help adolescents aged 12–18 with type 1 diabetes improve their blood sugar control, pancreatic function, and cholesterol levels. Sixty participants were randomly assigned to eat the oat flakes or a c…

This study tested whether taking a melatonin supplement (3 mg each night for 6 months) could improve sleep, thinking skills, and blood sugar control in 70 adolescents with type 1 diabetes. Half received melatonin and half received a placebo. The researchers measured changes in bl…

This study tested whether a daily probiotic capsule containing Lactobacillus johnsonii N6.2 is safe for adults with type 1 diabetes and whether it affects the immune system. 46 participants took either the probiotic or a placebo for 24 weeks. Researchers monitored blood counts, m…

This study tested whether a class of diabetes drugs called SGLT2 inhibitors can slow the progression of kidney disease in adolescents with type 1 diabetes. Researchers measured changes in urine protein levels and blood sugar control over 6 months in 86 participants aged 10-18. Th…

This small study tested a new tool called InsuLearn that helps people with type 1 diabetes calculate their insulin doses without needing to count carbohydrates. Seven adults on multiple daily injections used the tool for a day and were compared to their usual care. The goal was t…

This study tested whether giving insulin as an extended bolus (over time) instead of all at once helps control blood sugar after high-fat, high-protein meals in teens with type 1 diabetes. Thirty teens using a closed-loop insulin pump ate a standardized breakfast and received eit…

This study tested whether an enhanced continuous glucose monitor (eCGM) linked to a decision-support system can help older adults (65+) with type 1 diabetes manage their blood sugar. The system automatically uploads glucose, insulin, and activity data to give personalized insulin…

This study tested a new self-learning bolus calculator that simplifies meal announcements for adolescents and young adults with type 1 diabetes using automated insulin delivery. Two participants used the system first in a hotel and then at home to see if it was safe and feasible.…

This study tested whether resveratrol, a natural substance found in grapes and peanuts, could improve blood sugar control and kidney health in 60 teenagers with type 1 diabetes and early kidney damage. Participants took resveratrol tablets twice daily for 6 months. The study meas…

This study tested a visual injection site map to help people with diabetes rotate where they inject insulin. The goal was to reduce lipohypertrophy—lumpy fatty tissue caused by repeated shots in the same spot—and improve blood sugar control. 170 adults on insulin for at least six…

This study tested whether eccentric training (a type of exercise that lengthens muscles) done in a low-oxygen (hypoxic) chamber or with creatine supplements could improve blood sugar control, muscle strength, and fitness in people with type 1 diabetes. 28 adults with type 1 diabe…

This small pilot study tested whether a remote digital care program (TELEDUC-DIAB) could help 10 teens aged 12-17 with poorly controlled type 1 diabetes. Participants used a monitoring platform and educational app alongside their usual care. The main goal was to see if their bloo…

This study tested a program to help teens and young adults (ages 16-25) with type 1 diabetes better manage their blood sugar. The program focused on supporting their independence and self-care. 113 participants took part to see if this approach could improve their long-term healt…

This study tested whether a probiotic called Lactobacillus johnsonii N6.2 is safe and affects the immune system in 30 children and teens with type 1 diabetes. The goal was to see if the probiotic could help preserve the body's ability to produce insulin by improving gut health. P…

This study tested a new insulin delivery system called Tandem Freedom in 10 adults with type 1 diabetes. Participants used their usual system at home for a week, then switched to the new system in a supervised hotel setting. The goal was to check safety and how well it controls b…

This study tested an artificial pancreas system that learns a person's exercise patterns to prevent low blood sugar (hypoglycemia) during and after moderate exercise. Fifteen adults with type 1 diabetes used the system for about 4 months, comparing it to a standard version. The g…

This early study tested whether transplanting insulin-making islet cells could help people with type 1 diabetes who already had a kidney transplant. Only 3 patients took part, and they stayed on anti-rejection drugs. The goal was to see if the procedure was safe and could reduce …

This study looked at how well the TouchCare Nano automated insulin delivery system works for children and teens with type 1 diabetes in everyday life. Researchers tracked 76 kids aged 6 to 18 over six months to see if the system helped them spend more time with healthy blood suga…

This early-phase trial tested a new drug called VIS171 in 61 people: first in healthy volunteers, then in patients with autoimmune diseases. The main goal was to check safety and how the body processes the drug. No results on whether it actually helps the disease are available ye…

This study tested whether the Omnipod 5, a tubeless automated insulin pump, works better than multiple daily insulin injections for managing type 1 diabetes. 189 children and adults participated. The main goal was to see if the pump improved blood sugar control (HbA1c) over 13 we…

This study looked at how safe and effective Fiasp, a faster-acting mealtime insulin, is for people with type 1 or type 2 diabetes in everyday life. 42 adults used Fiasp as prescribed by their doctor for about 6 months. Researchers tracked side effects and blood sugar control to s…

This study tested whether using a continuous glucose monitor (CGM) in the hospital right after childbirth could better detect low blood sugar (hypoglycemia) in women with type 1 or type 2 diabetes, compared to standard finger-stick tests. Thirty-nine women in their third trimeste…

This early-phase study tested a new medicine called NNC0363-1063 in 117 healthy volunteers and people with type 1 diabetes. The goal was to check safety, how the body processes the drug, and its effect on blood sugar. The study had three parts, including single and multiple doses…

This study followed 30 adults with type 1 diabetes who used the Smartguard system, a partially automated insulin pump that can pause insulin delivery when it predicts a low blood sugar. The goal was to see how well the system works in everyday life, focusing on time spent in the …

This early study tested a new approach called Stem Cell Educator therapy in 13 adults with type 1 diabetes. The treatment involves taking a patient's own blood cells, processing them with stem cells, and returning them to the body. The main goal was to see if it is safe and feasi…

This study tested a special educational tool for parents of children under 6 with type 1 diabetes. The goal was to see if the tool could help parents better control their child's blood sugar and prevent serious events like low blood sugar or ketosis. The study enrolled 24 childre…

This early-phase study tested whether a colon-targeted butyrate tablet (BKR-017) could help people with type 1 diabetes improve insulin sensitivity and lower triglycerides. Six adults with type 1 diabetes took the tablets for 28 days alongside their usual care. The goal was to se…

This study tested whether a serious computer game called DIVE helps children aged 10-17 with newly diagnosed type 1 diabetes learn about their disease. 78 kids played the game twice a week for at least an hour, covering topics like diet and treatment. Researchers measured their k…

This study tested a mobile app that teaches teenagers with type 1 diabetes how to better manage their condition. 96 teens aged 12-18 were split into two groups: one used the app, the other received standard care. Researchers measured changes in diabetes knowledge, self-confidence…

This study tested whether sending supportive text messages to teenagers with poorly controlled type 1 diabetes could help lower their blood sugar levels. 92 teens aged 12-21 with high HbA1c levels participated. The approach used mobile phone reminders to encourage better diabetes…

This study tested whether taking low-dose aspirin (150 mg) daily, starting in the first trimester, could reduce pregnancy complications in women with type 1 or type 2 diabetes. The trial included 137 women and looked at outcomes like preeclampsia, early preterm birth, low birth w…

This study tested whether using a very tight glucose target (80-99 mg/dL) in an advanced hybrid closed-loop insulin pump (CamAPS FX) improves blood sugar control in adults with type 1 diabetes who had poor control. Forty participants who previously used multiple daily injections …

This study tested an experimental cell therapy called REACT (rilparencel) in 53 adults with type 1 or 2 diabetes and chronic kidney disease. The therapy involves injecting a person's own kidney cells into their kidneys to see if it can slow the loss of kidney function. The goal i…

This pilot study tested DiaBuddy, a mobile app designed to help children with type 1 diabetes and their families make better decisions about insulin dosing and managing sick days. Twenty-five children aged 5 to 18 used the app for three months. The study found that the app's reco…

This study tested whether a faster-acting insulin (Fiasp) works better than standard rapid insulin (NovoRapid) in insulin pumps for children and teens with type 1 diabetes. Researchers looked at blood sugar levels 30 minutes, 1 hour, and 2 hours after meals using real-world data …

This phase 2 trial tested whether infusions of PROCHYMAL, a stem cell product, could safely help people recently diagnosed with type 1 diabetes. The study enrolled 63 participants aged 12–35 who had been diagnosed within the past 20 weeks. Researchers measured how well the pancre…

This study followed 410 people with type 1 diabetes who use closed-loop insulin pumps—devices that automatically adjust insulin delivery. Researchers measured how well these pumps control blood sugar over time using HbA1c levels. The goal was to see if the pumps work effectively …

This small pilot study tested whether transplanting pancreatic islets together with parathyroid glands into the muscle could help people with type 1 diabetes stop using insulin. The 4 participants already had a functioning kidney or liver transplant and were on lifelong immunosup…

This study tested a program called FAM that helps adults with type 1 diabetes avoid dangerously high blood sugar, which can lead to diabetic ketoacidosis (DKA). The program involved sharing real-time glucose data with a family member or friend (the Follower), creating an action p…

This study compared time-restricted eating (eating only during a 6-8 hour window each day) to daily calorie restriction for weight loss and blood sugar control in 32 adults with type 1 diabetes and obesity. Participants followed their assigned diet while continuing insulin and gl…

This study tested a program called 4T (Teamwork, Targets, Technology, Tight Control) for children and teens newly diagnosed with type 1 diabetes. The program uses continuous glucose monitor data to give personalized feedback to families. Researchers measured changes in blood suga…

This study tested whether real-time remote blood sugar monitoring and secure texting could help teens (ages 13-18) with poorly controlled type 1 diabetes improve their blood sugar levels. Twenty teens wore a continuous glucose monitor that shared their readings with the study tea…

This study looked at 100 adults with type 1 diabetes who had diabetic ketoacidosis, a serious complication. Researchers compared three insulin approaches: one without basal insulin, one with basal insulin, and one with both basal and bolus insulin. The goal was to see which metho…

This study tested whether a faster-acting insulin (Lyumjev) works better than standard insulin (Humalog) in a dual-hormone artificial pancreas for people with type 1 diabetes. Twelve adults who already used the artificial pancreas took part. Each person used both insulins for 30 …

This study tested whether combining text message reminders with small rewards (behavioral economics) could help 173 teens with type 1 diabetes take their insulin more consistently. Participants used an insulin pump and had a history of missing mealtime doses. The goal was to impr…

This early-stage study tested a new treatment called IBC with MAS-1 in 21 adults recently diagnosed with type 1 diabetes. The goal was to see if it is safe and can retrain the immune system to stop attacking the pancreas, potentially helping the body control blood sugar naturally…

This study tested an automated insulin delivery system (a smart pump) in 15 adults with type 1 or type 2 diabetes who also had advanced kidney disease or were on dialysis. Participants used the system for 8 weeks, then switched to their usual care for another 8 weeks. The goal wa…

This study tested a new insulin patch pump in 161 adults with type 1 or type 2 diabetes who needed intensive insulin therapy. Participants used either the new patch pump or a standard pump for 7 days in a hospital. Researchers measured changes in average blood sugar levels to see…

This study looked at 83 people with diabetes and early-stage eye disease. It compared having laser treatment in one session versus four sessions to see which approach better controls the disease and reduces the risk of swelling in the center of the eye. The main goal was to measu…

This study tested a small, wearable sensor that sits just under the skin and measures blood sugar continuously for up to 5 days in adults with diabetes. 247 participants wore the sensor along with a standard monitor and took fingerstick tests to compare accuracy. The goal was to …

This study tested whether a new map for insulin injection sites (either digital or paper) could reduce skin lumps caused by insulin. 170 adults with diabetes who had been using insulin for at least six months took part. The map helped people rotate injection spots, aiming to impr…

This study tested the safety and effectiveness of the Omnipod 5 SmartAdjust 2.0 system, an automated insulin pump, in 48 people aged 2 to 70 with type 1 or type 2 diabetes. The system uses a continuous glucose monitor to automatically adjust insulin delivery. The main goals were …

This study tested a fully automated system that delivers both insulin and glucagon to manage blood sugar in adults with type 1 diabetes. Over 12 months, 243 participants used either the dual-hormone device or their usual care. The goal was to see if the system helps keep blood su…

This study looked at whether a low-carbohydrate diet could help children and teens (ages 10-18) with type 1 diabetes manage their blood sugar better. Twenty-five participants followed the diet for a short time, and researchers measured their blood glucose levels. The goal was to …

This study tested whether adding a community health worker to the diabetes care team helps children with type 1 diabetes. The health worker provided home visits, social support, and help with setting health goals. The study included 84 children and looked at blood sugar control, …

This study tested whether a sleep coaching program could help young adults (ages 18-26) with type 1 diabetes sleep longer and improve their blood sugar levels. Participants received personalized sleep advice and weekly check-ins over several weeks. The goal was to see if better s…

This study looked at whether using a smart insulin pen (NovoPen 6) with two insulins (Tresiba and Fiasp) helps people with type 1 diabetes achieve better blood sugar levels. About 411 adults took part for 9-11 months, using their own continuous glucose monitor and a mobile app to…

This study tested whether combining two safe immune therapies—abatacept injections and nasal insulin—can help preserve the pancreas's ability to make insulin in people recently diagnosed with type 1 diabetes. The goal is to make blood sugar control easier and reduce the need for …

This study looked at whether alerts from continuous glucose monitors (CGMs) help hospital patients with type 1 or 2 diabetes manage their blood sugar better. Over 500 adults who needed intensive insulin therapy took part. The main goal was to see if alerts increased the time bloo…

This study tested a personalized telemedicine coaching program for children with type 1 diabetes who have difficulty adjusting their insulin therapy. Over 100 children received phone and secure message coaching from nurses for 6 months. The goal was to improve blood sugar control…

This study looked at how aerobic and resistance exercise impact blood sugar levels after eating in children and teens (ages 10-18) with type 1 diabetes. Forty-nine participants did different types of exercise, and their blood sugar was tracked for six hours after meals. The goal …

This pilot study tested whether shared medical appointments (group visits) could help underserved children aged 8–12 with poorly controlled type 1 diabetes. The 14 participants attended group visits every 3 months for a year, focusing on using diabetes technology and improving bl…

This study tested two versions of an artificial pancreas in 15 adults with type 1 diabetes. One version used only insulin with automatic carb suggestions, while the other added glucagon to prevent low blood sugar. Participants underwent exercise and meal challenges to see which s…

This study compared a new version of the Omnipod insulin pump (SmartAdjust 2.0) to the current Omnipod 5 in 132 people with type 1 or type 2 diabetes, ages 2 to 70. Participants used each system for about a month to see if the new one is safe and helps keep blood sugar in a healt…

This Phase 3 trial tested a new fast-acting insulin called THDB0206 against a standard insulin (lispro) in 550 Chinese adults with type 1 diabetes. Both groups also used a long-acting insulin (glargine). The main goal was to see if THDB0206 could control blood sugar (HbA1c) as we…

This study tested whether trained peer mentors (ages 20-35) could help young adults (ages 17-25) with type 1 diabetes better control their blood sugar and smoothly move from pediatric to adult diabetes care. 144 participants were randomly assigned to receive peer support or usual…

This study tested a mobile app called Diactive-1 that guides children and teens with type 1 diabetes through resistance exercises like squats and band pulls. Over 24 weeks, researchers tracked whether the app helped lower daily insulin doses. The trial enrolled 62 participants ag…

This study looked at how well an artificial pancreas system (the Tandem t:slim pump with Control-IQ Technology) works for teenagers with Type 1 Diabetes during puberty. It followed 42 adolescents aged 11-13 for two years, comparing the device to usual care. The goal was to see if…

This study tested a smart system that combines a Bluetooth-enabled insulin pen with a continuous glucose monitor to help people with type 1 diabetes manage their blood sugar. 179 participants used either the smart system or standard insulin injections and glucose monitoring for 6…

This study tested a new medicine called dasiglucagon against the standard glucagon for treating severe low blood sugar in Asian adults and Japanese teens with type 1 diabetes. About 38 participants received both drugs in random order to see if dasiglucagon raises blood sugar just…

This study tested a new fast-acting insulin (faster aspart) against a standard insulin (NovoRapid) in 331 adults with type 1 or type 2 diabetes. Both were taken with a long-acting insulin (insulin degludec) for 16 weeks. The goal was to see if the new insulin works better at cont…

This study looked at whether taking a fast-acting insulin (Insulin Aspart) before or after meals makes a difference in blood sugar control for people with type 1 diabetes who use an insulin pump. Twenty-two adults participated, and their blood sugar was tracked continuously for 1…

This study compares a new once-weekly insulin (icodec) to a standard daily insulin (degludec) in 582 adults with type 1 diabetes. Participants receive either weekly or daily injections, plus mealtime insulin, for about a year. The goal is to see if the weekly option controls bloo…

This study looked at how quickly a fast-acting insulin (faster aspart) enters the blood in 23 Chinese adults with type 1 or type 2 diabetes. Participants received one injection of faster aspart and one of the standard insulin NovoRapid, in random order. Blood samples were taken o…

This early-phase study tested whether a new type of immune cell, called a tolerogenic dendritic cell, is safe for people with type 1 diabetes. The cells were made from each patient's own blood and designed to calm the immune system attack on the pancreas. 32 participants received…

This study tested whether transplanting insulin-making islet cells could help people with type 1 diabetes who already had a kidney transplant. Fourteen participants received up to three infusions of donor islet cells along with steroid-free immunosuppression. The goal was to see …

This small study tested a new insulin delivery system called Tandem Freedom in 10 adults with type 1 diabetes. Participants first used their usual system at home for a week, then switched to Tandem Freedom in a supervised hotel setting. The main goals were to check for severe low…

This study looked at 76 children with type 1 diabetes to see if a different way of calculating insulin doses before meals could improve blood sugar control. The children used their usual rapid-acting insulin (glulisine, aspart, or lispro) via a pump. The goal was to find which me…

This study tested an automated insulin delivery system (the Omnipod 5) in 130 hospitalized adults with type 1 or type 2 diabetes. Patients were randomly assigned to use the automated system or standard insulin injections plus a continuous glucose monitor. The goal was to see if t…

This early-phase trial tested the safety of a new drug called R-5280, a modified starch, in 9 children aged 11-17 who were recently diagnosed with type 1 diabetes. The study compared R-5280 to a placebo (food-grade starch) and monitored side effects and blood sugar levels over 12…

This study tested a connected insulin management platform in 36 people with type 1 or type 2 diabetes who use insulin. The goal was to see if the platform helped them take their insulin doses on time and keep their blood sugar in a healthy range. Participants used a continuous gl…

This study tested a continuous glucose monitor (CGM)-based advisory system to help adults with type 1 diabetes better manage their blood sugar. The system gives personalized advice based on glucose readings and the person's behavior and mindset. The goal was to improve glucose co…

This Phase 3 trial tested whether finerenone, a drug already approved for kidney disease in type 2 diabetes, can also slow kidney damage in people with type 1 diabetes. 241 adults with both conditions took either finerenone or a placebo for 6 months, alongside their usual care. R…

This study tested whether using wireless continuous glucose monitors (CGM) in the hospital can help manage blood sugar levels for people with type 1 or high-risk type 2 diabetes. 157 patients wore the monitors, which sent real-time glucose readings to a care team that could adjus…

This study looked at whether the MiniMed 780G insulin pump, when used with a continuous glucose monitor, is safe for children aged 2 to 6 years with type 1 diabetes. Fifty-six children used the system at home. The main goals were to measure how often their blood sugar stayed in a…

This study tested a new insulin infusion set designed to be worn for up to 7 days instead of the usual 2-3 days. 260 adults with type 1 diabetes used the set at home for 12 wear periods. The goal was to see if the set could safely deliver insulin for a full week without causing h…

This study looked at whether the Minimed 780G, an automated insulin pump system, helps people with type 1 diabetes keep their blood sugar in a safe range during surgery. Researchers analyzed data from 15 patients who used the system before, during, and after their operation. The …

This study tested the Omnipod 5, an automated insulin delivery system, against standard insulin pumps in 196 adults with type 1 diabetes. Participants used their usual therapy for 14 days, then either switched to Omnipod 5 or stayed on their pump for 90 days. The goal was to see …

This study tested a hybrid closed-loop insulin delivery system (Control-IQ) in 30 adults with type 1 diabetes. The system combines an insulin pump with a continuous glucose monitor that automatically adjusts background insulin. Participants used the system for 52 weeks, and resea…

This pilot study tested whether high doses of omega-3 fatty acids (fish oil) and vitamin D are safe and can help preserve insulin production in people with type 1 diabetes. The trial included 27 participants, both children and adults, who had diabetes for up to 10 years. Research…

This pilot study tested an artificial intelligence system that helps manage insulin delivery in young children (ages 2 to 6) with type 1 diabetes. The system combines a continuous glucose monitor, an insulin pump, and an AI advisor that adjusts pump settings automatically. Thirty…

This study tested a mobile app called EkiYou V2 that helps people with diabetes figure out how much insulin to take. 21 adults who use multiple daily insulin injections used the app for 6 weeks. The goal was to see if the app safely improves blood sugar control and makes insulin …

This completed Phase 4 trial enrolled 400 youth aged 7-25 with type 1 diabetes in low-resource settings. It compared insulin glargine (a long-acting analogue) to standard human insulin (NPH or premixed) to see if glargine reduces serious hypoglycemia or improves time in blood sug…

This pilot study tested two computer algorithms designed to automatically control blood sugar levels in people with type 1 diabetes. Five adults who already use an insulin pump and continuous glucose monitor participated. The goal was to see if the systems could keep blood sugar …

This study tested a new feature for automated insulin delivery systems: a priming bolus that automatically delivers a small amount of insulin before a meal. The goal was to see if it helps keep blood sugar in a healthy range after eating. Fifteen adults with type 1 diabetes parti…

This study looked at a device called GLOBAFFIN that filters antibodies from the blood to help people with autoimmune diseases. It involved 34 adults and measured how much harmful antibodies were removed and if patients felt better. The goal was to see if the device is safe and wo…

This study tested a weekly injection of semaglutide (a drug used for type 2 diabetes and weight loss) in 115 adults with type 1 diabetes and obesity who already use an automated insulin pump. The goal was to see if adding semaglutide helps improve blood sugar levels, reduce hypog…

Researchers are evaluating four blood glucose meters and four HbA1c point-of-care devices to see how accurately they measure blood sugar and long-term glucose control compared with standard lab methods. The study includes people with diabetes, both adults and teenagers, some of w…

This study investigates whether hearing problems are an under-recognized complication of diabetes. Researchers will screen 172 adults with type 1 or type 2 diabetes using hearing tests and a questionnaire. If a hearing issue is found, a more detailed assessment will be done to de…

This study tested a new device called LabPatch, a small patch worn on the arm that measures blood sugar levels continuously. Researchers compared its accuracy to standard lab tests and two commercial glucose meters. The study involved 30 adults with type 1 or type 2 diabetes to s…

This study looked at new markers in blood and urine to detect and predict the severity of drug-associated acute pancreatitis in adults. Researchers compared these markers in 175 patients with drug-induced pancreatitis, other pancreatic diseases, and healthy volunteers. The goal i…

This completed trial tested how accurately the True Vie I3 continuous glucose monitor measures blood sugar levels in 159 adults with type 1 or type 2 diabetes. Participants wore the device while researchers compared its readings to standard lab measurements. The goal was to see i…

This study tested a new continuous ketone monitoring (CKM) system in 16 adults with type 1 diabetes who use insulin pumps. Participants wore the CKM sensor for 14 days and followed special diets with a short insulin stop to see if the device accurately measures ketones compared t…

Researchers at Stanford University are testing whether the Diabetes Body Project, a six-session group program, can reduce eating disorder symptoms and improve blood sugar control in young women with type 1 diabetes. The study enrolls 55 female-identifying participants aged 15 to …

This phase 4 trial tests whether taking metformin daily before 20 weeks of pregnancy can reduce the risk of high blood pressure disorders, like preeclampsia, in pregnant women with type 1 diabetes. About 60 women will receive either metformin plus standard care or standard care a…

This study tested whether giving a daily mix of two types of friendly bacteria (Lactobacilli) to children at genetic risk could prevent or slow down autoimmune diseases like celiac disease, type 1 diabetes, and thyroid problems. The researchers enrolled 202 children who already h…

This completed study tested whether sending behavioral nudges through Denmark's official electronic letter system could increase flu vaccination among adults aged 18-64 with chronic diseases. Over 300,000 participants were randomly assigned to receive different types of letters o…

This study tested a video-based telemedicine program called REDCHiP for parents of young children (ages 2-6) with type 1 diabetes. The program uses education, behavior training, and therapy to reduce parents' fear of hypoglycemia (low blood sugar). 396 families participated, comp…

This trial tests whether a 14-week mindfulness-based cognitive behavioral program can improve quality of life and blood sugar control in adults with type 1 or type 2 diabetes. Participants will be randomly assigned to either the program or routine diabetes care. The study measure…

This study looks at whether watching an animated film or reading a storybook can lower fear and anxiety in children aged 7 to 12 who have just been diagnosed with type 1 diabetes. About 64 children will take part, and their anxiety levels will be measured using special child-frie…

This trial tests whether a quick cold spray on the skin before a subcutaneous insulin injection can reduce pain compared to a placebo spray. Adults in the emergency department who need at least two insulin injections receive both sprays in random order, rating their pain after ea…

This study tests whether a self-help app called MyDiaMate can reduce diabetes distress in adults with type 1 diabetes. Researchers are enrolling 660 participants across the Netherlands, UK, Spain, and Germany. The app aims to support mental health alongside usual care.

This study tested custom-made insoles for people with diabetic foot to see if they improve balance and walking. Twenty-five participants aged 40 to 65 with early-stage diabetic foot issues were included. The insoles were designed using pressure measurements to offload high-pressu…

This study tested a group telehealth program called TREAT-ED for young adults aged 18-26 with type 1 diabetes. The program used video sessions led by a diabetes educator to teach self-management skills. The goal was to see if this approach could improve participation in diabetes …

This study tested a smartphone app called SNAQ that estimates the carbohydrate content of a meal from a single photo. The goal was to see if using the app helps people with type 1 diabetes keep their blood sugar in a healthy range. 44 adults who already use an automated insulin p…

This study tested a program called PREP-DC that teaches teens and young adults with type 1 diabetes how to communicate better with their doctors and get ready for adult diabetes care. 52 participants aged 17-23 were split into two groups: one received the program, the other got s…

This study tested a program called T1DES designed to help Black young adults aged 18-30 with type 1 diabetes feel less stressed about their condition. Researchers wanted to see if the program was practical and could improve blood sugar levels and emotional well-being. The study i…

This study tested a smart technology platform with a serious game for 200 adolescents with type 1 diabetes. The game was designed to help them build emotional and social skills, cope with their condition, and improve quality of life. Researchers measured changes in well-being, em…

This study tested a culturally tailored education and support program called T1DES for Black young adults aged 18-30 with type 1 diabetes. The goal was to see if the program could reduce diabetes distress and improve blood sugar control. Forty-three participants received either s…

This study tested a 7-session anti-stigma psychoeducation program for adults with Type 1 diabetes. The goal was to see if it could reduce feelings of stigma and improve quality of life. 36 participants completed the program and were compared to a group that did not receive it. Re…

This study tested whether personalized text messages could help young adults with type 1 diabetes feel more confident managing their condition as they moved from pediatric to adult care. 234 participants received either usual care or usual care plus a text messaging program. The …

This study tested how easy and convenient the DuraTouch® device is for injecting insulin. 128 people with type 1 or type 2 diabetes used the device for 12 weeks and rated their satisfaction. The goal was to see if the device improves the daily injection experience.

This study looked at whether a diet low in salt and sugar can reduce common side effects of corticosteroid treatment, such as weight gain, high blood pressure, and diabetes. Fifty adults with autoimmune diseases or asthma who were starting high-dose corticosteroids were randomly …

This completed study tested a behavioral program for 217 teens and young adults (ages 14-25) with type 1 diabetes. The program included 12 one-on-one sessions focused on improving blood sugar levels and reducing diabetes-related distress. Researchers measured changes in time in r…

This study tested two devices—Coolsense (cold) and Buzzy (cold + vibration)—to see if they could reduce pain and fear in children aged 6-12 during insulin injections. 90 kids with type 1 diabetes were split into three groups: one used Coolsense, one used Buzzy, and one received s…

This study tested a smartphone app called Petit Cactus that uses photo recognition to help people with type 1 diabetes count carbohydrates. 73 participants used the app for 3 months while researchers tracked how often they logged meals, their blood sugar control, and user satisfa…

This study tested a program where community health workers helped young adults (ages 18-35) from underrepresented minority groups with type 1 diabetes start using devices like continuous glucose monitors and insulin pumps. Over 9 months, 119 participants were randomly assigned to…

This study tested whether adding a 12-week home-based high intensity interval training program to standard education about preventing low blood sugar (hypoglycemia) helps adults with type 1 diabetes who have lost the ability to sense low blood sugar. 47 participants were randomly…

This study tested whether regular nurse counseling could help teenagers with type 1 diabetes feel more in control of their condition and improve their blood sugar levels. 77 teens aged 13-18 with poorly controlled diabetes took part. One group received routine care, while the oth…

This study looked at whether exercising before or after lunch is better for controlling blood sugar in women with type 1 diabetes, including those who are pregnant. Twenty women participated, and researchers measured how much time their blood sugar stayed in a healthy range over …

This study tested three different programs to help adults with type 1 diabetes manage the stress and worry that often comes with the condition. 296 participants were split into groups, each trying a different approach: one focused on emotional awareness, another on problem-solvin…

This study tested whether an online mindfulness program could help adults with type 1 or type 2 diabetes lower their blood sugar. Over 300 participants with high stress and poor glucose control were randomly assigned to either an 8-week Mindfulness-Based Stress Reduction course o…

This study tested a mobile app that gives personalized encouragement and health insights based on blood sugar, exercise, mood, and sleep patterns. The goal was to help 24 middle-aged adults with type 1 diabetes or similar conditions exercise more often and confidently. The app ai…

This completed study tested a behavioral program called ONBOARD for 150 adults with type 1 diabetes who were not using continuous glucose monitors regularly. The program taught skills to overcome common barriers like managing data and social situations. The goal was to help parti…

This study is collecting blood, urine, and stool samples from 500 children with autoimmune diseases and healthy controls. Researchers will analyze these samples to find molecular patterns that could help diagnose these conditions and guide treatment decisions. The goal is to crea…

This study looks at how the menstrual cycle changes blood sugar and energy use in women with type 1 diabetes. About 40 women will use a closed-loop insulin pump and continuous glucose monitor to track these changes. The goal is to understand how hormone shifts affect insulin need…

This completed study in Kazakhstan looked at 240 adults recently diagnosed with diabetes. Researchers measured blood sugar, insulin resistance, and immune markers to understand how different forms of diabetes develop. The goal is to help doctors diagnose and treat adult-onset dia…

This study looked at 719 people, including patients with autoimmune connective tissue diseases like myositis, their blood relatives, and healthy volunteers. Researchers collected blood samples and medical histories to find genetic and environmental factors that may trigger these …

This study explored how family members share health information about genetic diseases like sickle cell, diabetes, and cancer. Over 1,000 adults completed surveys or interviews about their family health history and support. The goal was to understand social and relational factors…

This observational study looks at records from Israel's National Insurance Institute to understand how often diabetes is linked to permanent disability. It will compare disability rates and severity across different regions and over time, from 2020 to 2025. No treatments or tests…

This study tests how well the adhesive parts of a future patch pump stick to the skin of children aged 7 to 17 who need insulin for diabetes. The device is a dummy—it has no electronics and just mimics the shape and weight of a real pump. Researchers will see if the patch stays a…

This study looks at how type 2 diabetes affects young people aged 12 to 25. Researchers want to see if giving the pancreas a 2-week rest with insulin shots can improve its ability to make insulin. Participants take metformin, follow a diet, and some also get insulin. The study al…

This study looks at whether adrenaline, the body's stress hormone, triggers an immune reaction during low blood sugar (hypoglycemia) in people with and without type 1 diabetes. Researchers will lower participants' blood sugar and then give drugs that block adrenaline's effects to…

This study looks at how type 1 diabetes affects the heart, lungs, and overall fitness of children aged 6 to 17. It also measures their physical activity levels and quality of life. Researchers will compare these results with those of healthy children of the same age. The goal is …

This study investigates how women with type 1 diabetes manually adjust their automated insulin delivery (AID) systems to manage blood sugar changes during their menstrual cycle. Researchers will interview 69 women to catalog strategies like entering fake carbohydrates or changing…

This early study tests whether two modified insulins (diluted U-200 Humalog and diluted U-500 Humulin) work faster than a current rapid insulin (Lyumjev) in 20 adults with type 1 diabetes who use insulin pumps. Participants receive each insulin after a meal, and researchers measu…

This study tests how well a dummy patch pump (with no electronics or medicine) sticks to the skin of 175 adults with insulin-requiring diabetes. The goal is to see if the adhesive can stay on for 5 to 7 days in different body locations. The results will help design a future comme…

This study investigates whether exercising in the morning versus the afternoon changes how the body handles blood sugar and burns fat in people with type 1 diabetes. Twelve adults with type 1 diabetes will do one hour of moderate exercise at 9 AM and another session at 4 PM on se…

This study investigates why athletes with type 1 diabetes often experience higher blood sugar during competitions compared to regular training. Researchers will monitor 12 athletes with type 1 diabetes and 12 healthy athletes during a 5K race and a 5K training session, measuring …

This study tests French versions of three questionnaires that measure fear of low blood sugar (hypoglycemia) in children with type 1 diabetes and their parents. The goal is to ensure these tools are reliable for French-speaking families. About 194 children aged 2 to 18 and their …

This study looked at how the heart fills and pumps blood when the body is tilted or exposed to lower body pressure. Researchers compared 30 people with type 1 diabetes and healthy volunteers. They used heart monitoring and ultrasound to measure changes, aiming to understand how d…

This study looked at 347 children and teens with type 1 diabetes who use the Medtronic MiniMed 780G insulin pump. Researchers tracked how much carbohydrate they ate each day and measured their blood sugar control over time. The goal was to understand the link between daily carb i…

This completed study looked at how well Danish hospitals followed official guidelines for managing blood sugar in people with diabetes who had major, non-cardiac surgery. Researchers reviewed records from over 13,000 patients treated between 2017 and 2023. They focused on whether…

This study investigates whether stress hormone activity is linked to depression and brain changes in children with type 1 diabetes. Researchers will measure cortisol levels and use brain scans in children aged 6–12 who have had diabetes for at least a year, comparing them to thei…

This study checked how well two continuous glucose monitors (Dexcom G6 and FreeStyle Libre) work when oxygen levels are low. Thirty people with type 1 or type 2 diabetes took part. Researchers compared sensor readings to blood tests during controlled low-oxygen conditions to see …

This completed study followed over 1,000 children with newly diagnosed type 1 diabetes and their healthy siblings for up to three years. Researchers collected genetic information, measured diabetes-related antibodies, and asked about environmental exposures. The goal was to build…

This study looked at how a new insulin (NNC0363-1063) interacts with a non-glucose carbohydrate (a type of sweetener) in 36 adults with type 1 diabetes. Participants received fixed doses of the insulin and different amounts of the carbohydrate in random order over 4 tests. The go…

This study tested whether a special heart ultrasound (speckle tracking strain echocardiography) can detect early heart muscle changes in 61 adults with type 1 diabetes, before symptoms appear. Researchers looked for links between these changes and small blood vessel damage (micro…

This completed study looked at 238 people who received a pancreas and kidney transplant for type 1 diabetes. The goal was to understand why diabetes sometimes returns even after a new pancreas is working. Researchers checked for immune system markers, like antibodies and T cells,…

This completed study looked at how rising temperatures affect people with chronic conditions like heart disease, diabetes, and depression. Researchers in Germany and Italy surveyed 176 patients to see what symptoms they experienced during heat and what protective steps they took.…

This study looked at over 13,000 people with chronic inflammatory rheumatism or autoimmune diseases who had or were suspected to have COVID-19. Researchers tracked how many developed severe COVID-19 requiring intensive care or leading to death. They also examined risk factors lik…

This study looked at how the COVID-19 lockdown changed blood sugar control and self-care in 77 young people aged 13 to 25 with type 1 diabetes. Researchers used data from a glucose monitoring platform to compare blood sugar levels before, during, and after the two-month lockdown …

This study tested a digital program that monitors both the emotional well-being of caregivers and the glucose levels of children with type 1 diabetes. Thirty families used the system for two months to see if it was practical and easy to use. The goal was to learn how stress and b…

This study looked at whether people with severe, long-term uncontrolled type 1 diabetes would accept and benefit from a closed-loop insulin delivery system (an 'artificial pancreas'). Researchers followed 66 adults with very high blood sugar levels over several years. The goal wa…

This completed study tested a new biosensor designed to measure blood glucose every 10 minutes in people with type 1 diabetes who use an insulin pump. The sensor uses microdialysis to sample interstitial fluid and was compared to standard continuous glucose monitors (CGM) during …

This study looked at whether getting an islet transplant after a kidney transplant helps people with type 1 diabetes avoid kidney failure or death. Researchers reviewed data from 327 people in France who had a kidney transplant between 2000 and 2017. They compared those who also …

This study looked at how type 1 diabetes and long-term blood sugar control (HbA1c) affect the body's ability to deliver and use oxygen during exercise. Researchers compared 79 people with and without diabetes to understand why fitness levels may be lower in those with high blood …

This study tested a new way to help young adults (ages 18-30) with type 1 or type 2 diabetes move from pediatric to adult diabetes care. Researchers compared a collaborative care model to usual care, looking at how many visits patients completed and changes in diabetes-related di…

This study looked at whether cutting basal insulin by half before exercise helps keep blood sugar stable in people with type 1 diabetes. Eighteen active adults using insulin pumps completed two treadmill sessions—one with the insulin reduction and one without. Researchers measure…

This completed trial tested whether electronic alerts in the emergency room can improve care for people with type 2 diabetes. The alerts prompted doctors to order an A1c test when blood sugar was very high, and to consider admitting the patient for better diabetes management. Res…

This completed study looked at how two substances—GIP, a natural gut hormone, and alanine, an amino acid from protein—work together to release glucagon, a hormone that raises blood sugar. Researchers tested 10 people with and without type 1 diabetes to see if combining GIP and al…

This study looked at how the nervous system helps control blood sugar in people with type 1 diabetes who had islet cell transplants. Nine participants received drugs that block nerve signals or a placebo during controlled low blood sugar experiments. The goal was to learn whether…

This completed study surveyed 166 adults with type 1 diabetes to understand what factors influence their choice of hybrid closed-loop (artificial pancreas) systems. Participants included those already using, waiting to start, or considering such technology. The goal was to learn …

This completed study looked at why people with type 1 diabetes lose their natural defense against low blood sugar—the hormone glucagon. Researchers tested whether blocking a hormone called GLP-1 with a drug (exendin(9-39)amide) could restore glucagon release during low blood suga…

This pilot study tested whether continuous glucose monitors (CGMs) can help manage blood sugar in hospitalized adults with diabetes. Forty patients wore a Dexcom G6 device during their hospital stay to track glucose levels. The goal was to see if CGM could reduce dangerous low or…

This study looked at how eating disorders, like anorexia or bulimia, impact blood sugar levels in women with type 1 diabetes. Researchers compared glucose control between those with and without eating disorders. The goal was to better understand these risks and improve screening …

This completed study followed 73 people with autoimmune diseases like rheumatoid arthritis or multiple sclerosis who were starting treatment with rituximab. The goal was to track how many developed serious infections and to understand what factors increase that risk. Researchers …

This study tested a smartphone-based tool called PEPPER that gives personalized insulin dose advice to people with type 1 diabetes. The tool uses artificial intelligence to learn from each person's past data and includes safety features like low-glucose alarms. Eight adults used …

This study examined how the menstrual cycle affects blood sugar and insulin needs in 77 women with type 1 diabetes. Using data from continuous glucose monitors and insulin pumps, researchers compared the follicular and luteal phases. The goal is to help women adjust their diabete…

This study tested a questionnaire that measures nutrition knowledge in Turkish adolescents with type 1 diabetes. Researchers enrolled 150 teens to see if the tool is reliable and valid. The goal is to help future studies and improve diabetes care by linking nutrition knowledge to…

This study tested five different blood glucose meters in 501 adults with type 1 or type 2 diabetes who use insulin. Participants used multiple devices to see how accurate and reliable each meter is in real-world conditions. The goal was to help people with diabetes and their doct…

This completed study looked at 189 adults with type 1 diabetes who used one of three advanced hybrid closed-loop insulin pump systems: Medtronic Minimed 780G, Tandem T Slim X2, or CamAPS Fx. The goal was to see which system helped patients keep their blood sugar in a very tight r…

This study looked at how non-caloric artificial sweeteners (like those in diet drinks) affect body composition, metabolism, and blood sugar control in 21 youth aged 5-17 with type 1 diabetes. Researchers measured body fat and muscle using special scans and tested blood for marker…

This completed study looked at 115 young people aged 10 to 25 with type 1 diabetes in Spain. Participants filled out an online survey about their mental health, eating habits, and how well they manage their diabetes. The goal was to see if these factors differ by age and sex, and…

This study checked how well children with type 1 diabetes and their brothers or sisters follow the recommended vaccination schedule. Researchers looked at vaccination records from 60 children. The goal was to see if kids with diabetes are up to date on their shots, not to test a …

This study looked at whether giving oral glucose at a slightly higher blood sugar threshold can prevent mild-to-moderate hypoglycemia in people with type 1 diabetes. Thirty adults with type 1 diabetes were given 16g of oral carbohydrates when their blood glucose reached a target …

This pilot study tested two automated insulin delivery systems (Medtronic 780G and Tandem t:slim X2) in 20 adolescents with type 1 diabetes. Participants ate breakfasts without telling the device how many carbs they were eating. The goal was to see how well each system controlled…

This study looked at how automated insulin delivery (AID) systems, including homemade DIY versions, perform in physically active adults with type 1 diabetes. Over six weeks, 76 participants wore their own AID systems and a fitness tracker while sharing glucose and insulin data. T…

This study tested whether special communication training for pharmacists and general practitioners helps them involve older patients in decisions to stop or lower medications for heart disease and diabetes. Researchers enrolled 310 patients aged 75 and older who were taking certa…

This study tested whether taking acetaminophen (like Tylenol) interferes with a new continuous glucose monitor called Biolinq. Thirty-one adults with diabetes wore the Biolinq sensor and a standard CGM for three days. On day three, they took acetaminophen and researchers compared…

This study looked at how diabetes changes the way certain fats (arachidonic acid) are processed in fatty plaques that build up in the carotid artery. Researchers compared plaque samples from 204 diabetic and non-diabetic patients undergoing surgery for carotid stenosis. The goal …

This study looked at whether improving blood sugar control can restore a protein called apoC1, which helps reduce bad cholesterol. Researchers compared 160 type-1 diabetes patients with poor blood sugar control to 80 healthy controls. They took blood samples to measure how well a…

This study tested whether people with diabetes can use a smartphone game to monitor their vision at home, instead of always going to the clinic. 55 participants at high risk for diabetic retinopathy played vision games on their phones for 6 months. The goal was to see if people w…

This study tested whether simulation (a kind of role-play) can help adults with insulin-dependent diabetes learn to use the Freestyle Libre glucose monitor. Twenty-seven patients who had already completed a standard education program took part. The goal was to see if simulation i…

This study looked at how type 1 diabetes affects bone health in children and teens. Researchers compared bone density and structure in 86 children with and without diabetes using special scans. The goal was to understand if diabetes makes bones more fragile, which could lead to b…

This study looks at whether using an automated insulin delivery system (a smart insulin pump and continuous glucose monitor) along with a low-carbohydrate diet can help restore the body's natural glucagon response to low blood sugar in people with type 1 diabetes. The glucagon re…

This study followed 87 active adults with type 1 diabetes who use automated insulin pumps and exercise at least twice a week. Researchers tracked their blood sugar levels before, during, and after exercise to see how well the pumps handle physical activity. The goal was to learn …

This study looked at how different types of exercise—short bursts of intense cycling versus steady moderate cycling—affect blood sugar levels in adults with type 1 diabetes. It also compared exercising after a meal versus on an empty stomach. Twenty-one physically active adults c…

This study looked at whether measuring pancreatic polypeptide levels after a meal can help doctors tell the difference between type 1 diabetes and type 3c diabetes (caused by pancreas damage). Thirty-six adults with either type 1 or type 3c diabetes gave blood and stool samples. …

This study measured how common post-traumatic stress disorder (PTSD) is in adults with type 1 diabetes, focusing on PTSD related to the initial diabetes diagnosis or a severe hypoglycemic event. Researchers gave 297 participants questionnaires to check for PTSD symptoms. The goal…

This completed study looked at 825 adults with type 1 diabetes who use an insulin pump to see how many also have obstructive sleep apnea. Researchers used overnight oxygen tests and sleep studies to find cases. The goal was to understand if sleep apnea is linked to diabetes compl…

This study looked at whether viral infections and diabetes in pregnant women are linked to congenital heart defects in their babies. Researchers analyzed blood and stool samples from 114 women to detect viruses and immune responses. The goal was to gather knowledge for future lar…

This study looked at 186 pregnant women with type 1 or type 2 diabetes to understand how fats in the blood relate to baby birth weight. Researchers measured blood fats, diet, and placenta genes. The goal is to find new ways to prevent babies from being born too large, which can c…

This study looks at how pancreas-kidney transplantation changes bile acids and gut-related metabolism in people with type 1 diabetes and kidney disease. Researchers will measure bile acid levels and glucose responses in 50 transplant patients, comparing them to kidney-only transp…

This study looked at 62 people with type 1 diabetes to see if a test that measures the hormone glucagon can predict the risk of dangerously low blood sugar (hypoglycemia). Participants drank a special liquid meal or received an arginine injection to stimulate glucagon release, an…

This study followed 512 children born to parents with type 1 diabetes to see if early immune system changes and other factors could predict who might develop the disease. Researchers looked at blood markers, gut bacteria, and family environment. The goal was to better understand …

This completed study followed 1,290 adults with type 1 or type 2 diabetes for two years. Researchers tracked mental health issues like depression, anxiety, and eating problems alongside daily blood sugar levels using smartphone surveys and continuous glucose monitors. The goal wa…

This study tested a computer-adaptive questionnaire to see if it can accurately measure the emotional well-being of caregivers of children with type 1 diabetes. 108 caregivers answered questions that changed based on their responses, aiming for a more personalized assessment. The…

This early-phase study tested the safety and tolerability of a new drug called LAD191 in 69 healthy adults and people with an autoimmune disease. Researchers gave single or multiple doses to see how the body processes the drug and if it causes side effects. The goal was to gather…

This completed study looked at how diet and exercise change blood sugar levels in 61 adults with diabetes. Researchers used advanced tests (genomics, proteomics, etc.) to understand the body's complex response. The goal is to build a tool that helps doctors personalize diabetes c…

This study looked at whether immune cell responses can serve as a simpler way to measure how many insulin-producing beta cells remain in people with type 1 diabetes. Researchers followed 156 participants over 30 months, using meal tests and blood/urine samples. The goal was to fi…

This study tested whether a special education program helps children with type 1 diabetes learn more about their condition and feel better. 68 children and teens from one hospital in France took part. They answered questionnaires about diabetes knowledge and quality of life. The …

This study looked at how many girls and young women aged 11 to 20 with chronic diseases (like diabetes or immune conditions) got the HPV vaccine, compared to those without chronic illness. Researchers reviewed records of 223 participants from a hospital in France. The goal was to…

This study tested whether it is possible to run diabetes education workshops for inmates at Paris' La Santé prison. 22 men with type 1 or type 2 diabetes took part in group classes covering diet, foot care, and medication. The main goal was simply to see if prisoners would attend…

This study looked at how often sleep apnea occurs in adults with type 1 diabetes. Researchers monitored 53 participants overnight using standard sleep tests and continuous glucose monitors. The goal was to measure the link between sleep-disordered breathing and blood sugar contro…

This study looked at whether eating fewer carbohydrates could help people with type 1 diabetes become more sensitive to insulin and improve blood vessel health. Fourteen adults on insulin pumps tried both a low-carb diet and a standard diet for one week each. The results showed n…

This study tested whether a Diabetes Navigator—a personal guide—helps people with type 1 diabetes use advanced devices like continuous glucose monitors and insulin pumps more effectively. 148 participants were randomly assigned to get navigator support or standard care. The main …

This study looked at how often older adults with diabetes in long-term care facilities experience low blood sugar (hypoglycemia). Researchers used a continuous glucose monitor (CGM) worn for 10 days to track blood sugar levels in 86 participants. The goal was to better understand…

This study tested a mobile app designed to help young people with type 1 diabetes learn how to manage their condition. Twenty teens aged 10-18 used the app at home for 12 weeks. Researchers measured how often they used the app and checked their blood sugar control.

This study from Yale University looked at what happens when teenagers with type 1 diabetes follow a very low carbohydrate diet for two weeks. Nineteen participants ate either a low-carb or standard diet to see how it affected their blood sugar levels and brain function. The goal …

This study looked at how stress, anxiety, and depression affect daily diabetes care in teens and young adults (ages 13-26) with type 1 diabetes. Participants used their smartphones to answer quick surveys throughout the day while wearing a continuous glucose monitor. The goal was…

This early study tests whether the antidepressant fluoxetine (Prozac) can improve the body's nervous system response during exercise in people with type 1 diabetes. Many with diabetes avoid exercise due to fear of low blood sugar. The study includes 64 adults—half with type 1 dia…

This study compares two versions of insulin lispro—one standard strength and one double-strength—to see if they work the same in the body. About 90 adults with type 1 diabetes will receive a single dose of each in random order. The goal is to check if the stronger formula is bioe…

This study tested whether an online training platform called SUPPORT-Pro could increase healthcare professionals' confidence in treating people with type 1 diabetes. The platform provides evidence-based, regularly updated content on topics like medication, diet, and glucose monit…

This study tested a website called SUPPORT that provides online courses and a discussion forum to help adults with type 1 diabetes better manage low blood sugar (hypoglycemia). Researchers wanted to see if the platform was satisfying, engaging, and could reduce fear and frequency…

This completed study followed over 8,600 children from birth to identify environmental factors—like infections or diet—that may trigger type 1 diabetes in those with genetic risk. Researchers tracked the appearance of diabetes-related autoantibodies and the development of the dis…

This study tested whether an online peer support group on Discord is helpful and easy to use for teens aged 16-19 with type 1 diabetes. Ten participants joined the group for 3 months and gave feedback. The main goal was to see if teens would use it and like it, not to measure blo…

This study looks at 55 adults with diabetes who are either allergic to insulin or not, to better understand and diagnose insulin allergy. Researchers will test a step-by-step diagnostic approach and study the immune system's role. The goal is to make it easier to identify the exa…

This study looked at whether oxytocin, a natural hormone, can improve the body's ability to release glucagon during low blood sugar (hypoglycemia) in people with type 1 diabetes. Sixteen adults with type 1 diabetes received both oxytocin and a placebo on separate days to compare …

This study looked at whether counting protein and fat, in addition to carbohydrates, helps control blood sugar after meals in adolescents with type 1 diabetes. Eleven teens using insulin pumps ate standard and high-fat-high-protein meals, and their blood sugar, hormones, and fatt…