Can two immune therapies save the pancreas in type 1 diabetes?
NCT ID NCT05742243
First seen Jan 05, 2026 · Last updated May 22, 2026 · Updated 21 times
Summary
This study tested whether combining two immune therapies—abatacept (injected weekly) and nasal insulin (sprayed daily then twice weekly)—can help preserve the pancreas's ability to make insulin in people recently diagnosed with type 1 diabetes. 68 participants aged 6 to 21 took part for 48 weeks of treatment plus 48 weeks of follow-up. The goal is to make blood sugar control easier and reduce the need for injected insulin, though ongoing insulin use is still expected.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Perth Children's Hospital
Nedlands, Western Australia, 6009, Australia
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Queensland Children's Hospital
South Brisbane, Queensland, 4101, Australia
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The Children's Hospital at Westmead
Westmead, New South Wales, 2145, Australia
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The Royal Children's Hospital
Parkville, Victoria, 3052, Australia
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The Royal Melbourne Hospital
Parkville, Victoria, 3050, Australia
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Women's and Children's Hospital
North Adelaide, South Australia, 5006, Australia
Conditions
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