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Could a gut pill help type 1 diabetes? small trial explores Butyrate's potential

NCT ID NCT03999853

First seen Jan 11, 2026 · Last updated Jun 02, 2026 · Updated 25 times

Summary

This early-phase study tested whether a colon-targeted butyrate tablet (BKR-017) could help people with type 1 diabetes improve insulin sensitivity and lower triglycerides. Six adults with type 1 diabetes took the tablets for 28 days alongside their usual care. The goal was to see if this supplement could be a helpful add-on therapy, not a replacement for insulin.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States

Conditions

The condition(s) this trial relates to.

type 1 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.