Diet soda danger? study probes artificial sweeteners in teens with diabetes
NCT ID NCT03889522
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how non-caloric artificial sweeteners (like those in diet drinks) affect body composition, metabolism, and blood sugar control in 21 youth aged 5-17 with type 1 diabetes. Researchers measured body fat and muscle using special scans and tested blood for markers of kidney and liver function, cholesterol, and blood sugar control. Participants also reported their intake of artificial sweeteners through questionnaires. The goal was to see if these sweeteners are linked to health risks in this group.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- non-caloric artificial sweeteners (dietary consumption)
- What this could lead to
- If results show a link, it could guide dietary recommendations for youth with type 1 diabetes to reduce future complication risks.
- What could go wrong
- This is a small, observational study with only 21 participants, so findings may not apply broadly. It only looks at associations, not cause and effect.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
21 people
The number who actually took part.
- Started
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May 2019
- Finished
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Feb 2021
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Youth receiving care at the Children's Hospital of Wisconsin Diabetes Clinic.
- Ages
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5 to 17 years
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Males and females aged 5-17 years with a clinical diagnosis of T1D of ≥ 6 months in duration 2. BMI between the 5th and 95th percentile Exclusion Criteria: 1. Presence of severe, active disease that requires the use of chronic medication, with the exception of well-controlled autoimmune thyroiditis/hypothyroidism or celiac disease that is well-controlled on a gluten free diet. 2. Diabetes other than T1D 3. Chronic illness known to affect glucose metabolism 4. Psychiatric impairment, with the exception of well-controlled depression or anxiety, that will affect the ability to participate in the study 5. Female participants of child-bearing age with reproductive potential must not be knowingly pregnant 6. Any condition that, in the investigator's opinion, may compromise study participation or may confound the interpretation of the study results
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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