University Of Michigan
Clinical trials sponsored by University Of Michigan, explained in plain language.
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App aims to improve heart failure management through daily tracking
Disease control CompletedThis study tested a mobile app designed to help people with heart failure monitor their blood pressure, weight, and heart rate daily. The app also tracks symptoms and medications, sharing the data with doctors to guide treatment. Researchers wanted to see if using the app leads t…
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Can a video game teach job skills to people with autism?
Disease control CompletedThis study tested a computer program called Work Chat that helps young adults with autism practice conversations with coworkers, customers, and supervisors in a virtual workplace. 44 participants used the tool to improve social skills needed for jobs. The goal is to help more peo…
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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AI-Powered therapy shows promise in curbing teen violence
Disease control CompletedThis study tested two versions of a remote therapy program for teens (ages 14-24) who came to the emergency room for a violent injury. One version was standard, the other used artificial intelligence to adapt the therapy in real time. The goal was to see if the AI version could b…
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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New One-Visit crowns put to the test
Disease control CompletedThis study tested a new type of ceramic crown that can be made and placed in a single dental visit, avoiding the need for temporary crowns. Fifty adults with decayed, fractured, or poorly filled molars or premolars received these crowns and were followed for up to five years. The…
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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New study settles debate: surgery or PT for torn rotator cuff?
Disease control CompletedThis study compared surgery to physical therapy for people with rotator cuff tears (a common cause of shoulder pain). 187 adults aged 40-84 with MRI-confirmed tears were randomly assigned to either arthroscopic surgery or physical therapy. The goal was to see which treatment bett…
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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Coaching lowers blood pressure in kidney patients
Disease control CompletedThis study tested whether an educational worksheet plus health coaching could help people with chronic kidney disease improve their blood pressure. 320 adults with moderate to severe kidney disease and uncontrolled high blood pressure took part. The goal was to see if the coachin…
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Could an antidepressant shield the brain in Parkinson's?
Disease control CompletedThis study tested whether taking citalopram for 26 months could slow the buildup of harmful amyloid plaques in the brain area responsible for visual thinking in people with Parkinson's disease. Fifty-eight participants aged 65 and older were randomly assigned to receive either ci…
Phase: PHASE2 • Sponsor: University of Michigan • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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Money stress and diabetes: new study tests a Two-Pronged solution
Disease control CompletedThis pilot study tested whether combining financial navigation (help with costs) and peer support (connecting with others) can help adults with diabetes better manage their condition. 61 participants were randomly assigned to receive either financial navigation alone or financial…
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Jun 27, 2026 09:11 UTC
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New dosing method may better prevent infections in overweight surgery patients
Disease control CompletedThis study looked at how to best dose an antibiotic (cefazolin) in overweight patients having surgery to prevent infections. Researchers compared the standard method (dosing based on body weight) with a new method (dosing based on body composition from CT scans). They measured an…
Phase: PHASE4 • Sponsor: University of Michigan • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Air purifiers may lower blood pressure in seniors near roadways
Disease control CompletedThis study tested whether using HEPA air purifiers at home could improve heart health in seniors living near busy roads. Fifty-two low-income seniors aged 60 and older used either a real air purifier or a sham device for four weeks. Researchers measured their blood pressure to se…
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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Smart app aims to optimize heart failure meds
Disease control CompletedThis completed Phase 3 trial tested a web application called SmartHF in 225 adults with heart failure and reduced ejection fraction. The app analyzes patient data and gives personalized medication recommendations that patients can share with their doctor. The goal was to see if u…
Phase: PHASE3 • Sponsor: University of Michigan • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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Can dupixent calm mysterious skin flares?
Disease control CompletedThis study tested the drug dupilumab (Dupixent) in 10 people with a chronic skin condition called dermal hypersensitivity reaction. Participants received injections of dupilumab every two weeks for 24 weeks. Researchers looked at changes in immune cells in the skin and how much b…
Phase: PHASE4 • Sponsor: University of Michigan • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Shocking ACL recovery: electric pulses and eccentric lifts show promise
Disease control CompletedThis study tested whether adding neuromuscular electrical stimulation (NMES) and eccentric leg press exercises to standard rehabilitation can help people regain muscle strength and protect knee cartilage after anterior cruciate ligament (ACL) reconstruction. 135 participants who …
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Breakfast makeover: simple diet change may tame diabetes
Disease control CompletedThis study tested a 4-month online program that encourages a very low-carbohydrate breakfast for adults with poorly controlled type 2 diabetes. Researchers measured how satisfied participants were, how well they stuck to the diet, and changes in blood sugar, weight, and medicatio…
Phase: PHASE1, PHASE2 • Sponsor: University of Michigan • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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App aims to cut salt and lower blood pressure in hypertensive patients
Disease control CompletedThis study tested whether a smartphone app called LowSalt4Life can help people with high blood pressure reduce their sodium intake and improve blood pressure. The app provides tips and reminders to eat less salt. 410 participants with high blood pressure used the app, and researc…
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Keto diet battles plate method for diabetes control
Disease control CompletedThis study compared two diets for people with type 2 diabetes: a very low-carbohydrate (keto) diet and a plate-method diet. Over 12 months, researchers tracked blood sugar control and body composition in 182 participants. The goal was to see which approach better improves diabete…
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Could a common diabetes drug tame a tricky heart rhythm?
Disease control CompletedThis study looked at whether metformin, a drug usually used for diabetes, can help prevent atrial fibrillation (an irregular heartbeat) from coming back after a standard procedure called catheter ablation. About 117 non-diabetic adults with a higher body weight took metformin or …
Phase: PHASE4 • Sponsor: University of Michigan • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Could a smartphone camera spot blinding eye diseases?
Diagnosis CompletedThis study tests whether a smartphone-based camera can accurately screen for eye diseases such as diabetic retinopathy, glaucoma, and age-related macular degeneration. About 550 patients will have photos taken with both the smartphone camera and standard equipment. Ophthalmologis…
Sponsor: University of Michigan • Aim: Diagnosis
Last updated Jul 01, 2026 00:00 UTC
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New pap smear device aims to reduce pain and boost screening rates
Diagnosis CompletedThis study tested a new device called the Femscope Calm Collect Device for collecting cervical cells during cancer screening. The goal was to see if it could collect cells just as well as a traditional Pap smear but with less pain and discomfort. Thirteen healthy women aged 21-45…
Phase: NA • Sponsor: University of Michigan • Aim: Diagnosis
Last updated Jun 27, 2026 07:55 UTC
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Could a simple ultrasound replace radiation scans for kidney blockages?
Diagnosis CompletedThis study tested whether a special ultrasound with a contrast dye (Definity) can detect kidney obstructions. Ten adults with a blocked kidney had ultrasound scans before and after surgery to relieve the blockage. The goal was to see if this method works as well as standard nucle…
Phase: PHASE2 • Sponsor: University of Michigan • Aim: Diagnosis
Last updated Jun 27, 2026 07:52 UTC
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Can couples counseling curb HIV? new study tests dyadic approach in south africa
Prevention CompletedThis study tested whether a couples-focused counseling and testing program could help prevent HIV and improve care. 544 couples from rural South Africa took part. The goal was to see if this approach increases viral suppression and engagement in HIV care.
Phase: NA • Sponsor: University of Michigan • Aim: Prevention
Last updated Jun 27, 2026 13:05 UTC
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Online mentors shield trans teens from drugs and violence
Prevention CompletedThis study tested an online mentoring program for transgender and gender minority youth aged 14-18. The program paired each teen with an adult transgender mentor for seven 90-minute group sessions focused on building social and emotional skills. The goal was to prevent problems l…
Phase: NA • Sponsor: University of Michigan • Aim: Prevention
Last updated Jun 27, 2026 12:36 UTC
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Can a simple conversation save lives? new program targets safe gun storage in rural alaska
Prevention CompletedThis study tested a program called Family Safety Net in rural Alaska. It aimed to help families store firearms safely to prevent suicide and accidental injuries. 58 adults who lived with guns took part. Some received a counseling session, others a scripted talk, and all got free …
Phase: NA • Sponsor: University of Michigan • Aim: Prevention
Last updated Jun 27, 2026 12:35 UTC
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Can a therapy app keep kids safe from gun violence?
Prevention CompletedThis study tested a program called IntERact to see if it could reduce risky firearm behaviors like carrying or using a gun among urban youth ages 16 to 30. Participants were recruited from emergency departments in Flint and Saginaw, Michigan, and received therapy sessions plus a …
Phase: NA • Sponsor: University of Michigan • Aim: Prevention
Last updated Jun 27, 2026 12:24 UTC
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ER-based program aims to stop opioid addiction before it starts in young people
Prevention CompletedThis study tested new ways to prevent opioid misuse and addiction in teens and young adults (ages 16-30) who visited the emergency department. Participants received support starting in the ER and continuing through telehealth after they went home. The goal was to find the most ef…
Phase: NA • Sponsor: University of Michigan • Aim: Prevention
Last updated Jun 27, 2026 09:00 UTC
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Vaccine vans and imams join forces to boost child immunization
Prevention CompletedThis study tested two creative ways to increase childhood vaccination rates in Indonesia: sending mobile vaccine vans into neighborhoods and holding conferences with religious leaders. Over 2,400 adults participated in surveys about their children's vaccination status. The goal w…
Phase: NA • Sponsor: University of Michigan • Aim: Prevention
Last updated Jun 27, 2026 08:11 UTC
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Can a very Low-Carb diet beat standard advice for prediabetes?
Prevention CompletedThis completed study compared two versions of the Diabetes Prevention Program in 304 overweight adults with prediabetes. One group followed the standard lower-calorie, lower-fat diet, while the other tried a very low-carbohydrate diet. Researchers measured changes in blood sugar …
Phase: NA • Sponsor: University of Michigan • Aim: Prevention
Last updated Jun 27, 2026 08:05 UTC
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Simple wash may prevent Post-Surgery bruising and bleeding
Prevention CompletedThis study tested whether applying tranexamic acid (TXA) directly into the surgical wound during breast reduction or gender-affirming mastectomy could prevent hematomas—painful collections of blood under the skin. 107 adults participated. The goal was to see if this simple, low-c…
Phase: PHASE4 • Sponsor: University of Michigan • Aim: Prevention
Last updated Jun 27, 2026 08:00 UTC
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Texts and gadgets aim to keep kidney stones away
Prevention CompletedThis study tested whether digital tools like a smart water bottle, a fitness watch, and text reminders could help people with a history of kidney stones drink more water as their doctor recommended. 216 adults who had a kidney stone in the past 5 years and drank less than 2 liter…
Phase: NA • Sponsor: University of Michigan • Aim: Prevention
Last updated Jun 26, 2026 18:19 UTC
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Tai-Chi and lactulose combo tested to stop falls in liver patients
Prevention CompletedThis completed Phase 3 trial tested whether a combination of lactulose (a medicine) and virtual Tai-Chi (a gentle exercise) could reduce falls and other serious events in 230 people with cirrhosis and portal hypertension. Participants were randomly assigned to different sequences…
Phase: PHASE3 • Sponsor: University of Michigan • Aim: Prevention
Last updated Jun 26, 2026 15:25 UTC
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Can coaching help veterans use cannabis for pain?
Symptom relief CompletedThis study tests four virtual coaching sessions to help veterans with chronic pain use their own cannabis products more effectively. Participants will learn strategies to manage pain and related symptoms. The goal is to see if this coaching improves pain relief and satisfaction.
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jul 01, 2026 00:00 UTC
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New study tests simple strategies to combat loneliness and suicidal feelings
Symptom relief CompletedThis study looks at two treatments—Social Prescribing (connecting people with community activities) and Brief Cognitive Therapy (changing unhelpful thought patterns)—to see if they are practical and well-liked by adults who feel lonely or have suicidal thoughts. About 60 particip…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 14:02 UTC
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One massage session may ease shoulder pain after breast cancer
Symptom relief CompletedThis study looked at whether a 30-minute myofascial massage can reduce shoulder stiffness and improve blood flow in breast cancer survivors who have myofascial pain. Twenty-one women who had completed breast cancer treatment 3 months to 2 years earlier received one massage sessio…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 14:01 UTC
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Virtual reality workouts may keep aging brains fit
Symptom relief CompletedThis study tested whether an 8-week mixed reality exercise program could improve thinking and physical abilities in adults aged 60 and older with mild cognitive decline. Thirty participants were split into two groups: one did mixed reality cognitive-physical training, the other d…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Remote therapy helps seniors move more, hurt less
Symptom relief CompletedThis small study tested whether a 6-week remote occupational therapy program could help older adults living in affordable senior housing become more physically active and manage pain. Six residents took part in individual and group sessions led by an occupational therapist over v…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Feelings as medicine: could emotional awareness ease pain and opioid dependence?
Symptom relief CompletedThis pilot study tested whether an 8-week group therapy program delivered over Zoom could help adults with both chronic pain and opioid use disorder. The therapy, called Emotional Awareness and Expression Therapy (EAET), teaches people to understand and express their emotions as …
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 13:06 UTC
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Phone-Based program aims to boost mood and mobility in seniors
Symptom relief CompletedThis study tested a program called RESET, led by community health workers, to improve physical and mental well-being in older adults. Over 450 African American adults aged 50+ with symptoms like depression, anxiety, or chronic pain took part. The program included weekly group pho…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Church-Based therapy aims to lift depression in rural michigan
Symptom relief CompletedThis study tested a computer-assisted cognitive behavioral therapy program called Raising Our Spirits Together (ROST) for rural adults with depressive symptoms. The program was delivered in small groups by local pastors, either online or in person at churches. Researchers compare…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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New program helps seniors with memory loss manage chronic pain at home
Symptom relief CompletedThis study tested a 7-week program to help older adults with both chronic pain and mild memory problems manage their pain better. Participants received weekly phone coaching and watched educational videos. The goal was to see if the program was practical and could reduce how much…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
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New approach aims to prevent suicide in black teens
Symptom relief CompletedThis study tested a combination of two approaches for Black teenagers who came to the emergency room with suicidal thoughts or behaviors. The first is a type of talk therapy called Cognitive Behavioral Therapy for Suicide Prevention (CBT-SP), and the second is a support team made…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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Coach support boosts weight loss efforts in older adults
Symptom relief CompletedThis study tested whether adding a patient coach helps older adults with obesity follow their weight and health plan. 19 participants worked with a coach to address barriers to diet and physical therapy goals. The study measured how many attended appointments, achieved goals, and…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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Sleep therapy may boost alcohol recovery success
Symptom relief CompletedThis study tested two types of therapy for insomnia in 134 people also being treated for alcohol use disorder. The goal was to see if improving sleep could help them stay sober and feel better during the day. Participants received either a standard insomnia treatment or a tailore…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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Lay health workers may ease pain in seniors without pills
Symptom relief CompletedThis study tested whether community health workers (CHWs) can teach older adults with chronic pain how to manage their symptoms using a 7-week program called STEPS. The program included phone sessions with a CHW, online videos, and a wearable activity tracker. Researchers enrolle…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Can a website ease pancreatitis pain? small study tests online Self-Management
Symptom relief CompletedThis study tested whether a web-based self-management program is feasible and acceptable for people with chronic pancreatitis who have ongoing abdominal pain. Thirty-one participants were given access to a tailored website with pain management modules over 12 weeks. The goal was …
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Can an app beat fatigue in scleroderma? small study tests feasibility
Symptom relief CompletedThis study tested a smartphone app called RENEW designed to help people with scleroderma manage fatigue and build resilience. Over 12 weeks, 43 participants used the app to set and track weekly healthy goals. The main goal was to see if people would actually use the app and compl…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Exercise plus ketone drink shows promise for Parkinson's strength
Symptom relief CompletedThis study looked at whether combining exercise training with a ketone ester drink can improve muscle endurance and heart fitness in people with Parkinson's disease. Nineteen participants completed a cycling program while taking the supplement. Researchers measured changes in how…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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Can a 14-Minute video curb suicidal thoughts? new study tests 'Papageno' approach
Symptom relief CompletedThis study tested whether watching a 14-minute video of people sharing their personal stories of choosing not to attempt suicide can lower suicidal thoughts and hopelessness. Over 500 young adults who had recently wished they were dead watched either the 'Papageno' video or a con…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Can a chatbot ease caregiver stress? new study says maybe
Symptom relief CompletedThis study tested whether an AI therapy chatbot called Earkick could help support people caring for a loved one with dementia. 26 caregivers used the chatbot, and researchers measured how practical and acceptable it was. The goal was to see if this kind of technology could be a h…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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New support group aims to ease stress for black Alzheimer's caregivers
Symptom relief CompletedThis study tested a weekly video support group for Black family caregivers of people with Alzheimer's or related dementias. The goal was to see if the program could reduce stress and improve caregivers' confidence in managing care. Twenty-five caregivers participated in the pilot…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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Can a website help suicidal teens? new study tests digital support
Symptom relief CompletedThis study tested a website called eYST, designed to provide social support for teenagers at risk for suicide. Researchers wanted to see if the website was easy to use and helpful for 75 teens and their chosen support adults. The study focused on gathering feedback and measuring …
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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Shock therapy for belly pain? home device shows promise for pancreatitis
Symptom relief CompletedThis study tested a small, needle-free device that sends mild electrical pulses to specific points on the skin to relieve abdominal pain in people with chronic pancreatitis. 42 adults with long-term pancreas pain used the device at home for several weeks. The goal was to see if t…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 09:11 UTC
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Back pain relief might come from a piggy bank – no coins needed
Symptom relief CompletedThis study tested a 30-day program called Positive Piggy Bank for 200 adults with low back pain who were scheduled for a steroid injection. Participants did positive activities (like noting good things) or joined a waitlist. The goal was to see if the program improved daily funct…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Shocking the inner ear: a new hope for Parkinson's balance problems?
Symptom relief CompletedThis study looked at whether inner ear problems cause balance issues in Parkinson's disease and if a headset that stimulates the inner ear can help. 72 people with Parkinson's took part. They received a 20-minute stimulation session while researchers measured freezing of gait and…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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New online program aims to ease chronic pelvic pain without drugs
Symptom relief CompletedThis study tested a web-based program called My Pelvic Plan for people with chronic pelvic pain, including those with endometriosis. The program teaches pain education, cognitive and behavioral skills, acupressure, physical activity, and basic pelvic floor therapy. Researchers me…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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Glasses that shine light on postpartum depression
Symptom relief CompletedThis study tested a wearable morning light device (Re-Timer) for women with postpartum depression. 95 women wore either bright or dim light glasses for 60 minutes each morning for 5 weeks. Researchers measured changes in depression symptoms, sleep, and body clock timing. The goal…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC
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New device offers Drug-Free hope for pancreatitis pain
Symptom relief CompletedThis small pilot study tested a safe, non-invasive device that uses mild electrical pulses on the skin to help reduce belly pain in people with chronic pancreatitis. The goal was to see if patients would use the device at home and if it could be a drug-free option for pain. The s…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 09:01 UTC
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Podcasts and coaching help seniors take control of chronic pain
Symptom relief CompletedThis study tested a new program to help older adults manage chronic pain using educational podcasts and support from a community health worker. 40 people aged 50 and older with long-lasting pain took part. The program aimed to teach pain self-management skills and help participan…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 08:14 UTC
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Broccoli sprouts: the surprising new hope for gut health?
Symptom relief CompletedThis study tested whether eating steamed broccoli sprouts daily for 28 days could increase anti-inflammatory compounds in the blood and stool of people with mild ulcerative colitis. 23 participants took either 1 or 3 servings of sprouts per day. The goal was to see if this diet i…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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New wearable device aims to improve walking after stroke
Symptom relief CompletedThis study tested a low-cost wearable device called NewGait to see if it can help stroke survivors walk better. Twenty chronic stroke survivors tried the device and a similar one, while researchers measured their walking speed and muscle activity. The goal is to create an afforda…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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New surgery eases phantom limb pain by giving nerves a muscle home
Symptom relief CompletedThis study tested a surgical technique called Regenerative Peripheral Nerve Interface (RPNI) in 132 leg amputees to prevent or treat painful neuromas—nerve ends that form painful growths after amputation. The procedure involves implanting the cut nerve into a small piece of muscl…
Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Could a ketone drink help stabilize bipolar disorder?
Symptom relief CompletedThis small pilot study tested whether a ketone ester drink combined with a low-glycemic diet could help people with bipolar disorder. Fifteen adults with bipolar I or II took the supplement twice daily and made simple diet changes for several weeks. Researchers measured blood ket…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Can a weekly zoom group lift college Students' moods?
Symptom relief CompletedThis study tested a program called Mood Lifters for college students. 125 undergraduates attended 14 weekly virtual meetings to learn mental health strategies. The goal was to see if this low-cost, peer-led approach could reduce symptoms of depression, anxiety, and stress. Resear…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Zoom-Based program aims to get seniors moving with help from friends
Symptom relief CompletedThis study tested a 6-week program called T-VIDA, where seniors in a housing community met with an occupational therapist via Zoom and joined group sessions to increase physical activity. The program also involved respected community members to encourage participation. With only …
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Mind over muscle: mental training boosts ACL recovery
Symptom relief CompletedThis study looked at whether a type of mental coaching, called operant conditioning, could help improve thigh muscle strength and activation in people who had ACL surgery. Eleven adults aged 18-45 who had ACL reconstruction took part. The goal was to see if this brain-training ap…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Can an app ease MS fatigue and pain? small study says maybe
Symptom relief CompletedThis study tested how easy it is for people with multiple sclerosis (MS) to use a mobile app called MeTime MS. The app guides users through self-acupressure, a technique that involves pressing on specific points on the body to help with fatigue and pain. Ten adults with MS who ha…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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Simple exercise boosts mobility in Low-Income seniors
Symptom relief CompletedThis study tested a special exercise program for older adults living in low-income housing. The program combined different exercises and Tai Chi to help improve physical activity and daily function. 27 people aged 65 and older took part, and researchers measured their activity le…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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New study: Self-Monitoring exercise and massage eases pain in older women
Symptom relief CompletedThis study looked at whether self-monitoring physical activity and using a massage gun can reduce chronic pain in women aged 65 and older. 108 participants tracked their steps and massage use to see which habits best improved pain. The goal was to find simple, effective ways for …
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Coaching program aims to boost glaucoma medication adherence
Symptom relief CompletedThis study tested a six-month personalized coaching program for glaucoma patients who struggle to use their eye drops regularly. 236 participants received either coaching or standard care. The program used motivational interviewing and tailored education to help patients overcome…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Tiny study tests nerve block for kidney stone pain
Symptom relief CompletedThis study tested a procedure called an erector spinae plane block to see if it could help with pain from kidney stones. Only 5 people took part, all of whom had already received one pain medication in the emergency room. The results are very early and not enough to draw firm con…
Phase: PHASE2 • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Which stent hurts less? new study aims to ease kidney stone recovery
Symptom relief CompletedThis study looked at 224 adults with kidney or ureter stones who needed a stent after surgery. Half got a silicone stent, half got a standard plastic stent. The goal was to see which type caused less pain and interference with daily life in the days and weeks after surgery.
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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New combo therapy aims to boost quality of life for brain disorder patients
Symptom relief CompletedThis study tested whether a program that combines talk therapy, brain training, and healthy lifestyle advice is practical and helpful for people with conditions like mild traumatic brain injury, multiple sclerosis, long COVID, or mild cognitive impairment. Fifteen participants we…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Could a zapping cap boost your memory?
Symptom relief CompletedThis study tested a non-invasive brain stimulation technique called HD-tDCS in 269 people with mild cognitive impairment or early Alzheimer's. The goal was to see if different doses could improve brain connectivity and memory. Participants received the stimulation while researche…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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New study tests if adjustable sockets make prosthetics more comfortable
Symptom relief CompletedThis study compared adjustable prosthetic sockets to conventional ones in 29 people with leg amputations. Participants tried different sockets and reported comfort, mobility, and quality of life. The goal was to see if adjustable sockets offer benefits over standard ones.
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Wearable zaps could calm stomach pain in diabetes
Symptom relief CompletedThis study tested a wearable device that delivers mild electrical pulses through the skin, similar to acupuncture, to help relieve stomach symptoms in people with diabetic gastroparesis. 41 participants used the device at either a treatment point or a sham point for 84 days. Rese…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 26, 2026 13:07 UTC
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Brain scans reveal how a calming drug affects emotion in psychosis
Knowledge-focused CompletedThis study investigates how a medication called lorazepam, which boosts the calming brain chemical GABA, changes emotional brain activity in people with psychosis. Participants aged 16–60 with conditions like schizophrenia or bipolar disorder, along with healthy volunteers, will …
Phase: PHASE4 • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Fetal vs. postnatal surgery: which leads to better sleep breathing for spina bifida babies?
Knowledge-focused CompletedThis study looked at 173 infants with myelomeningocele, a severe form of spina bifida, to see if the timing of their surgery (before or after birth) affects their risk for sleep-disordered breathing. Researchers used sleep studies to measure breathing problems and later checked t…
Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:38 UTC
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App and bottle combo aims to flush away kidney stones
Knowledge-focused CompletedThis study tested a system called sipIT that uses a smart water bottle and phone app to track fluid intake and send reminders. The goal was to see if it helps kidney stone patients form a habit of drinking more fluids. 172 adults with a recent kidney stone diagnosis used the syst…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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New study reveals Dementia's toll on mexican american seniors
Knowledge-focused CompletedThis study looked at how common dementia and memory problems are in older Mexican Americans compared to non-Hispanic whites. Researchers tracked changes in thinking skills over time and also asked caregivers what help they need. The goal is to find better ways to support patients…
Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Obesity and antibiotics: study seeks safer dosing
Knowledge-focused CompletedThis study looked at how to give the antibiotic vancomycin to obese adults. Researchers compared dosing based on weight versus kidney function to see which gives better drug levels. 35 healthy obese volunteers received a single dose and provided blood and urine samples. The goal …
Phase: PHASE1 • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Ramadan fasting plus exercise: a promising combo for weight loss?
Knowledge-focused CompletedThis study looked at whether adding moderate aerobic exercise during Ramadan fasting helps overweight adults lose more fat and improve heart health compared to fasting alone. Twenty-eight participants were split into two groups: one only fasted, the other fasted and exercised fiv…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Your voice may reveal hidden liver risks
Knowledge-focused CompletedThis study looked at whether speech features—like how people sound and what they say—can help detect or predict confusion caused by liver disease (hepatic encephalopathy). Researchers recorded speech tasks from 251 participants with cirrhosis and tracked their thinking skills and…
Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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New constipation care plan shows promise in clinic test
Knowledge-focused CompletedThis study tested a new, faster care plan for people with chronic constipation at a University of Michigan gastroenterology clinic. Researchers wanted to see how often doctors ordered special tests and pelvic floor therapy, and how satisfied patients were with their care. The stu…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Baby bottle battle: does Mom's weight loss change how infants suck?
Knowledge-focused CompletedThis study looked at how babies suck on bottle nipples with different hole sizes. Researchers wanted to see if mothers who lost weight before pregnancy had babies with different sucking patterns. Ten mothers and their infants took part. The goal was to learn more about infant fee…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Treadmill trick may boost ACL recovery
Knowledge-focused CompletedThis study tested whether walking on a treadmill with belts moving at different speeds can improve how the knee loads weight after ACL reconstruction. Thirty-two participants who had ACL surgery within the past 10 months walked on the treadmill for 20 minutes. Researchers measure…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Flint study tests if community workshops can speed up stroke treatment
Knowledge-focused CompletedThis study tested whether community education and hospital improvements could increase the use of clot-busting drugs for stroke in Flint, Michigan. Researchers enrolled nearly 6,000 adult stroke patients across three hospitals. The community intervention included workshops, a mus…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Phone pings for better mood and sleep: study tests notifications on over 1,000 interns
Knowledge-focused CompletedThis study tested whether smartphone notifications could improve mood, physical activity, and sleep in over 1,000 medical interns. Participants received daily mood, activity, or sleep notifications through a mobile app. The study measured mood scores, step counts, sleep duration,…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Michigan study tests community-led strategies to boost COVID-19 shots
Knowledge-focused CompletedThis study aimed to increase COVID-19 vaccination among African American and Latinx communities in four Michigan counties. Researchers worked with community partners to understand why some people were hesitant to get the vaccine and tested ways to encourage uptake. Over 1,100 adu…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Can a text reminder boost teen violence screening? new study says maybe.
Knowledge-focused CompletedThis study tested whether extra engagement strategies, like reminders or feedback, help healthcare providers screen more teens for violence risk and deliver the SafERteens program. Researchers worked with 171 providers across multiple healthcare settings. The goal was to see if t…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Should seniors stop aspirin? new survey reveals their thoughts
Knowledge-focused CompletedThis study surveyed over 2,800 adults aged 65 and older in the US and Australia to understand their attitudes about stopping aspirin. Participants read a hypothetical patient scenario and shared their opinions on safety and helpfulness of continuing the medication. The goal is to…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Brain chemical dopamine may hold key to preventing falls in seniors
Knowledge-focused CompletedThis completed study looked at whether the brain chemical dopamine helps older adults maintain fast walking speed despite age-related changes. Five participants aged 60 and older with mild parkinsonian signs took carbidopa and carbidopa-levodopa for 10 days. Researchers measured …
Phase: PHASE1, PHASE2 • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Tiny study tests ultrasound as a new way to see bone around dental implants
Knowledge-focused CompletedThis small, completed study looked at whether ultrasound can help check the bone around dental implants as well as cone-beam CT scans do. Researchers measured bone thickness and height in 4 patients using both methods and compared them to photos taken during surgery. The goal was…
Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Hospital wellness program aims to boost patient satisfaction
Knowledge-focused CompletedThis study tested a program called the 'Inpatient Whole Health Bundle' to see if offering extra wellness items during a hospital stay improves patient satisfaction. About 97 adults staying in specific hospital units at the University of Michigan took part. Researchers compared th…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Can a wellness bundle make hospital stays better? VA study finds out
Knowledge-focused CompletedThis study tested a program called the Inpatient Whole Health Bundle, designed to improve well-being and satisfaction for hospitalized veterans. Over 600 patients at the VA Ann Arbor Healthcare System were offered wellness activities during their stay. Researchers then surveyed p…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Strength training for moms after tough pregnancies: a small step forward
Knowledge-focused CompletedThis study looked at whether a 4-week resistance training program is doable for women who had pregnancy complications like preeclampsia or preterm birth. Seven new moms participated, and researchers measured how well they stuck with the exercises and how they felt about them. The…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Hospital study tests 'Bonding Bundle' to boost doctor empathy
Knowledge-focused CompletedThis study tested whether a set of simple strategies, called the Bonding Bundle, could help doctors build better relationships with their hospitalized patients. Nearly 1,000 patients and their doctors took part. Doctors in the intervention group were asked to use specific approac…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Pharmacist alerts may beat doctor alerts for blood thinner safety
Knowledge-focused CompletedThis study looked at whether sending alerts to pharmacists instead of doctors helps improve how blood thinners (anticoagulants) are prescribed. Researchers tested two types of alerts with 306 healthcare providers. The goal was to see which method leads to faster and safer prescri…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Can you safely get another COVID shot after a bad reaction? new study says maybe
Knowledge-focused CompletedThis study looked at whether it is safe to give another dose of a COVID-19 mRNA vaccine to people who had a bad reaction to a previous dose, or to people with a history of allergies. It also included people with long COVID. A total of 137 adults took part and received either the …
Phase: PHASE4 • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Spinal zaps studied to Fine-Tune pain relief
Knowledge-focused CompletedThis study looked at how spinal cord stimulation (SCS) affects pain processing in 34 people with chronic pain. Participants already had an SCS device as part of their care. Researchers tested different stimulation patterns (burst, kHz, tonic, and sham) to see how they changed the…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Dentist education cuts opioid scripts for youth
Knowledge-focused CompletedThis study tested whether an educational program for dentists could reduce the number of opioid prescriptions they write for patients aged 13 to 30. Researchers compared prescribing rates before and after the training between dentists who received the program and those who did no…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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New therapy aims to curb suicide in schizophrenia patients
Knowledge-focused CompletedThis study tested a special type of talk therapy (Cognitive Behavioral Suicide Prevention for psychosis) to see if it could help adults with schizophrenia who have had recent suicidal thoughts or behaviors. About 51 people took part, and the therapy was compared to usual care. Th…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Art therapy for nurses: a new way to fight stigma in newborn care?
Knowledge-focused CompletedThis pilot study tested whether an online art-based training could reduce stigma that nurses may hold toward mothers who use substances during pregnancy. 99 registered nurses from labor, postpartum, and NICU units completed the training and surveys. The goal was to see if the tra…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Toothpaste and mouthrinse combo: which keeps fluoride in your mouth longest?
Knowledge-focused CompletedThis study tested how much fluoride remains in saliva after using different toothpastes (over-the-counter or prescription) followed by either water or a fluoride mouthrinse. Twenty healthy adults tried four different combinations. The goal was to see which routine keeps fluoride …
Phase: EARLY_PHASE1 • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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New DNA test could speed up infection treatment for diabetic foot ulcers
Knowledge-focused CompletedThis study tested whether a rapid DNA sequencing method (mNGS) could better identify bacteria in diabetic foot ulcers compared to standard lab cultures. 44 adults with diabetes and an infected foot ulcer had tissue samples analyzed using both methods. The goal was to see if this …
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Can breast cancer drugs speed up aging? new study investigates
Knowledge-focused CompletedThis observational study enrolled 94 women with breast cancer to see if it's possible to collect blood, stool, and survey data from older patients taking aromatase inhibitors (a type of hormone therapy). The main goal was to test the feasibility of gathering this information for …
Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Sweat and surgery: a One-Two punch against nerve damage?
Knowledge-focused CompletedThis study looked at whether high-intensity interval training (HIIT) or weight-loss surgery can reduce the risk of nerve damage (peripheral neuropathy) in people with obesity. About 140 adults who were candidates for bariatric surgery took part. Researchers measured nerve health …
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Gene study aims to personalize common heart drug
Knowledge-focused CompletedThis study looked at how genetic differences affect the activation of enalapril, a common blood pressure medication. Researchers gave 21 healthy volunteers enalapril for a week and measured drug levels in their blood. The goal was to see if a specific gene variant (G143E) changes…
Phase: PHASE4 • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Study tests if patients grasp their own Alzheimer's biomarker news
Knowledge-focused CompletedThis study looked at whether people with mild cognitive impairment or Alzheimer's-type dementia can understand and decide about receiving their PET scan results for amyloid and tau proteins. Researchers educated 152 participants and their care partners, then assessed their abilit…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Can VR job training keep Ex-Prisoners out of jail?
Knowledge-focused CompletedThis study tested whether virtual reality job interview training helps prisoners find jobs and avoid returning to crime. About 100 moderate-to-high risk offenders used a VR tool to practice interviews with a virtual hiring manager. Researchers compared their employment and re-arr…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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New study aims to prevent dangerous blood pressure drops during dialysis
Knowledge-focused CompletedThis study tested whether teaching dialysis staff and providing support to patients could reduce episodes of dangerously low blood pressure during treatment. Over 1,400 patients across multiple clinics took part. The goal was to make dialysis sessions safer and more stable.
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Personalized nudge boosts doctor dashboard use
Knowledge-focused CompletedThis study tested whether sending personalized emails with performance data would make urologists more likely to click on a quality dashboard, compared to a generic email. One hundred high-volume urologists from Michigan were split into two groups. The goal was to see if tailored…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Breath test may guide IBS-D treatment choices
Knowledge-focused CompletedThis study looked at whether a simple breath test can help predict which people with diarrhea-predominant irritable bowel syndrome (IBS-D) will respond to the drug rifaximin. 148 participants took rifaximin and completed breath tests and surveys. The goal was to see if the breath…
Phase: PHASE4 • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Can an internet course turn bystanders into lifesavers?
Knowledge-focused CompletedThis study tested whether an online course can effectively train laypeople in sub-Saharan Africa to provide emergency first aid for trauma injuries. Over 650 commercial drivers in Nigeria, Sierra Leone, Uganda, and Kenya took either an in-person or virtual half-day training cover…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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New website aims to empower patients against reproductive coercion
Knowledge-focused CompletedThis pilot study tested a website called BRIDGES that teaches family planning patients about reproductive coercion and how to stay safe. Researchers enrolled 156 people aged 18-29 at Planned Parenthood clinics in Michigan. The goal was to see if the website was easy to use and he…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Brain training shows promise for anxiety in small study
Knowledge-focused CompletedThis study tested whether real-time fMRI neurofeedback can help people with anxiety disorders better regulate their emotions. 21 participants practiced cognitive reappraisal while receiving feedback on their prefrontal cortex activity. The goal was to understand the brain mechani…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Can a virtual chat program boost job success for autistic adults?
Knowledge-focused CompletedThis study tested whether an online program called Work Chat could be delivered entirely over the internet to autistic adults. Researchers wanted to see if it was practical and if it helped with social skills like understanding hints and emotions. 234 employed or job-seeking auti…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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Back pain study aims to match patients to the right treatment
Knowledge-focused CompletedThis completed study with 494 participants looked at how different treatments for chronic low back pain work and who benefits most. Participants first tried an online pain management program, then those who didn't improve much were randomly assigned to mindfulness, physical thera…
Phase: PHASE4 • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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Digital vaccine card could boost shots for kids in africa
Knowledge-focused CompletedThis study tested a new digital vaccine card and mobile app in rural Uganda and urban Kenya to see if it helps more children get their vaccines on time. Over 3,500 children under 2 years old took part. Researchers checked how well the digital system worked for tracking shots like…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Text messages may help stressed students spot early warning signs
Knowledge-focused CompletedThis study looked at how first-year college students with mild-to-moderate depressive symptoms develop and cope with stress. 120 students participated, with some receiving weekly surveys and personalized feedback via text message. The goal was to see if this approach helps studen…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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AI assistant could slash pharmacy errors
Knowledge-focused CompletedThis study tested whether machine intelligence (MI) can help pharmacists catch medication dispensing errors. Sixty-eight licensed pharmacists completed mock verification tasks with and without MI advice. Researchers measured reaction time, accuracy, and trust in the AI to see if …
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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New study tests adaptive strategies to boost Kids' home workout adherence
Knowledge-focused CompletedThis study looked at whether a flexible, adaptive program can help children ages 8 to 12 stick to a home exercise routine. About 38 kids and their parents took part in a 60-day program where exercise videos and support were adjusted based on each child's progress. The goal was to…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Body scans may reveal who benefits from asthma biologics
Knowledge-focused CompletedThis study looked at CT scans from 233 severe asthma patients to see if body composition (like chest muscle size and quality) could predict how well they respond to biologic therapies. Researchers used advanced imaging analysis to find biomarkers linked to fewer asthma attacks. T…
Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Tiny nerve zaps may boost blood flow down there
Knowledge-focused CompletedThis small study tested whether mild nerve stimulation could increase vaginal blood flow in women with sexual problems, spinal cord injury, or no issues at all. Nine women had a small sensor placed in the vagina to measure blood flow changes during stimulation. The goal was to un…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Can better teamwork reduce burnout in family medicine clinics?
Knowledge-focused CompletedThis study tested a program to improve teamwork and reduce burnout among staff in five family medicine clinics. Over 600 staff members, including medical assistants, nurses, and doctors, took part. The program focused on helping different job roles communicate and collaborate bet…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Brain zaps and naps: can sound waves speed up anesthesia recovery?
Knowledge-focused CompletedThis study looked at how the brain processes what we see while under anesthesia. Researchers used brain scans (fMRI) to measure brain activity in 36 healthy adults during sedation with propofol. They also tested if using ultrasound on the brain could help people wake up faster. T…
Phase: PHASE2 • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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3D printed vs. traditional aligners: which hosts more mouth bacteria?
Knowledge-focused CompletedThis completed study at the University of Michigan compared how much bacteria builds up on 3D printed clear aligners versus conventional thermoformed aligners. Thirty participants wore each type of aligner for one week, and researchers swabbed both the aligners and tooth surfaces…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Can a therapy session boost use of the suicide lifeline for those with alcohol issues?
Knowledge-focused CompletedThis study looked at 488 adults with alcohol use disorder who had suicidal thoughts or attempts. Researchers wanted to understand why some people call the National Suicide Prevention Lifeline during a crisis and others don't. They also tested if a therapy session about the hotlin…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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What drives pelvic pain treatment decisions? new study digs in.
Knowledge-focused CompletedThis study looked at what factors influence how people with chronic pelvic pain view their treatment options. Researchers also tested whether a web-based program with self-guided modules (like acupressure, physical activity, and pelvic floor therapy) could change those views. 30 …
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Brain chemical clues may explain dementia alertness swings
Knowledge-focused CompletedThis study looked at why people with Lewy body dementia often have sudden changes in alertness. Researchers tested if a brain chemical called acetylcholine is involved and if gentle brain stimulation could help. Fifteen participants took part to gather information for future trea…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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New study aims to cut opioid prescriptions for new moms
Knowledge-focused CompletedThis study looked at how to help hospitals follow new guidelines for managing pain after childbirth, with the goal of reducing opioid use while still controlling pain effectively. Researchers worked with 69 hospitals in Michigan and tested two approaches: a basic training program…
Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Do videos help cirrhosis patients learn better than text?
Knowledge-focused CompletedThis study tested whether people with cirrhosis learn more from watching a video or reading text about their condition. 218 adults with cirrhosis took a quiz before and after receiving either a video or written educational material. The goal was to see which method improved knowl…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Smartphone study tracks how stress impacts blood sugar in young people with diabetes
Knowledge-focused CompletedThis study looked at how stress, anxiety, and depression affect daily diabetes care in teens and young adults (ages 13-26) with type 1 diabetes. Participants used their smartphones to answer quick surveys throughout the day while wearing a continuous glucose monitor. The goal was…
Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Survey reveals what older adults think about quitting daily pills
Knowledge-focused CompletedThis completed study surveyed 2,400 adults aged 65 and older in the United States and Australia. Participants read a fictional patient scenario and shared their preferences about starting or stopping a diabetes medication. The goal was to understand how older adults make decision…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Study explores why some patients respond better to physical therapy
Knowledge-focused CompletedThis pilot study looked at 30 people with chronic neck or shoulder pain from myofascial pain syndrome. Researchers wanted to see if certain pain features (called nociplastic pain) affect how well patients respond to physical therapy. Participants were followed for 3 months after …
Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:16 UTC
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Showing patients their spine images after injections may boost satisfaction
Knowledge-focused CompletedThis study tested whether doctors reviewing post-procedure X-ray images with patients after spine injections improves satisfaction. 141 adults with leg pain from pinched nerves participated. Two weeks later, patients filled out surveys about their care experience and how much the…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:38 UTC
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Pre-Pregnancy weight loss may boost Baby's health, study finds
Knowledge-focused CompletedThis study tested whether a very low energy diet (800 calories a day using meal replacements) before pregnancy could improve the health of obese women and their babies. 147 women participated, including those with obesity and healthy-weight women for comparison. Researchers measu…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:42 UTC