University Of Michigan

This study tested a web application designed to help people with a specific type of heart failure (HFrEF) get the best possible medications. 225 participants were randomly assigned to either use the 'SmartHF' app or receive usual care for 12 weeks. The app analyzed patients' heal…

This small pilot study explored whether adding steamed broccoli sprouts to the diet could help manage mild ulcerative colitis. Researchers tested if eating the sprouts increased certain beneficial compounds in the body and reduced gut inflammation markers. The goal was to see if …

This study tested two different training programs to make dialysis treatments safer for people with kidney failure. Researchers worked with 20 dialysis clinics to see if training healthcare teams or coaching patients could reduce dangerous drops in blood pressure during treatment…

This study tested whether a personalized educational worksheet and follow-up phone coaching could help people with chronic kidney disease (CKD) better manage their high blood pressure. 320 participants with moderate to severe CKD and uncontrolled blood pressure were assigned to r…

This study tested whether a personalized coaching program could help people with glaucoma use their eye drop medications more consistently. Researchers compared 236 patients who received motivational coaching and education to those who got standard care with extra handouts. The m…

This study tested whether using portable air filters in bedrooms could reduce seniors' exposure to fine air pollution particles (PM2.5) and improve heart health. Fifty-two non-smoking seniors living in an apartment building near road pollution participated. They used either real …

This study tested whether a smartphone app could help people with high blood pressure reduce their salt intake and improve their blood pressure. Researchers enrolled 410 adults with stable high blood pressure to use the app, which sent personalized reminders about healthy eating.…

This study tested whether a smartphone app and text reminders could help people who have had kidney stones drink more fluids to prevent new stones from forming. Researchers followed 172 adults in the U.S. for six months to see if the reminders helped them build and maintain bette…

This study tested if adding two special treatments to standard physical therapy helps people recover better after ACL knee surgery. The treatments were high-intensity muscle stimulation and specific strengthening exercises. Researchers wanted to see if this stronger rehab could b…

This study tested a new, faster care plan for people with chronic constipation. Researchers wanted to see if using this plan made doctors more likely to order specific tests and physical therapy for the pelvic floor muscles. They tracked 109 patients to see if the new approach im…

This project tested two different support programs to help 68 Michigan maternity hospitals follow new national guidelines for managing pain after childbirth. The goal was to safely reduce the amount of opioid painkillers prescribed to new mothers. Researchers compared a standard …

This study tested whether high-intensity interval training (HIIT) and weight-loss surgery could prevent or reduce nerve damage (neuropathy) in obese patients. Researchers followed 140 people from bariatric surgery clinics for two years, comparing a special exercise program to sta…

This study aimed to find out whether surgery or non-surgical treatment (like physical therapy) works better for people with rotator cuff tears that weren't caused by a sudden injury. Researchers followed 187 adults for one year, randomly assigning them to either get surgery or tr…

This study aimed to see if a simple breath test could help doctors predict which patients with diarrhea-predominant Irritable Bowel Syndrome (IBS-D) would respond well to the antibiotic rifaximin. About 148 adults with IBS-D took the breath test, received a 14-day course of rifax…

This small pilot study tested whether helping people with diabetes manage their medical costs and connecting them with a supportive peer could improve their health. 61 adults with diabetes who reported financial stress were randomly assigned to receive either financial help alone…

This study tested whether taking the antidepressant citalopram for over two years could slow the buildup of harmful brain plaques linked to thinking problems in Parkinson's disease. Researchers compared citalopram to a placebo pill in 58 older Parkinson's patients without depress…

This study tested whether adding the diabetes medication metformin to a standard heart ablation procedure helps prevent the return of atrial fibrillation (AFib), an irregular heartbeat. It involved 117 overweight adults without diabetes who were scheduled for ablation. Researcher…

This small, exploratory study tested whether a ketone supplement combined with a low-sugar diet could help people with bipolar disorder. Researchers enrolled 15 participants to see if this approach could improve mood stability and brain function. The main goal was to gather initi…

This study tested whether a simple, easy-to-follow program focused on eating a very low-carbohydrate breakfast could help adults with poorly controlled type 2 diabetes. Researchers enrolled 119 participants to try the 4-month online program, measuring if it was acceptable and if …

This study compared two different eating approaches to see which works better for managing type 2 diabetes. 182 participants with diabetes followed either a very low-carbohydrate diet or a plate-method diet for one year. Researchers measured how each diet affected blood sugar con…

This study tested whether a special dye used during an ultrasound scan could help doctors better see and measure blockages in the kidney's drainage system. Researchers compared scans of blocked and normal kidneys in 10 patients who were already scheduled for surgery to fix the bl…

This study tested a new device called the Femscope Calm Collect Device to see if it could make cervical cancer screening more comfortable and encourage more women to get tested. Researchers compared the new device to the traditional brush method in 13 adult women to see if it col…

This study tested a new, faster method to identify the specific bacteria causing infections in diabetic foot ulcers. Researchers compared the new test to standard lab cultures in 44 participants to see if getting results quicker could help doctors choose the best antibiotics soon…

This study tested whether people who had bad reactions to previous COVID-19 vaccines or infections could safely receive another vaccine dose. Researchers gave 137 adults either the Pfizer or Moderna COVID-19 vaccine and monitored them closely for allergic reactions. The goal was …

This study tested whether a combination of a medication (lactulose) and virtual Tai-Chi exercise classes could help prevent falls and other serious health problems in people with advanced liver disease (cirrhosis). 230 participants were randomly assigned to different sequences of…

This study tested whether a virtual reality job interview training program could help people leaving prison get jobs and avoid returning to crime. Researchers compared 101 prisoners who received the training plus usual services against those who received only usual services. The …

This study investigated whether losing weight before pregnancy improves health outcomes for both mothers and babies. Researchers compared a very-low-calorie diet to standard nutrition counseling in women with obesity. They measured how weight loss affected the mother's metabolism…

This study tested whether smart technology could help people with a history of kidney stones drink more water to prevent future stones. Researchers gave 216 participants smart water bottles, fitness trackers, and mobile apps that sent reminders to drink. The goal was to see if th…

This study tested two new ways to get more children vaccinated in Indonesia. Researchers wanted to see if bringing vaccines directly to communities with mobile clinics and holding discussions about vaccines at religious conferences would work better than standard clinics. They co…

This study tested a program to prevent risky gun behaviors in young people at high risk for violence. It involved 373 youth (ages 16-30) from Flint and Saginaw who reported recently carrying a firearm. The program combined three therapy sessions with a smartphone app that sent sa…

This study tested whether a very low-carbohydrate diet or the standard National Diabetes Prevention Program (NDPP) works better for people with prediabetes. Over 300 overweight adults with slightly high blood sugar were randomly assigned to follow one of the two diet plans for a …

This study tested a new educational website called BRIDGES, designed to help family planning patients understand and prevent reproductive coercion. Reproductive coercion is when a partner tries to control pregnancy or birth control decisions. The study involved 156 patients at Pl…

This study tested whether applying a drug called tranexamic acid (TXA) directly to the surgical area could safely prevent painful collections of blood called hematomas after breast surgery. It involved 107 people having breast reduction or gender-affirming mastectomy. Researchers…

This study tested whether watching a short video featuring interviews with people who overcame suicidal thoughts could help reduce risk factors for suicide. Researchers enrolled over 500 young adults who had experienced suicidal thoughts in the past year. They measured changes in…

This study tested whether telehealth support programs started during an emergency room visit could help prevent opioid misuse and addiction in young adults aged 16-30 who were already using opioids. Researchers worked with over 1,100 participants to find the most effective and af…

This pilot study tested a new online program called the Teen Connection Project. It paired 56 transgender and gender-diverse teens (ages 14-18) with adult mentors from similar backgrounds for seven group sessions. The goal was to see if building social and emotional skills throug…

This study tested whether having older women track their daily physical activity, their use of a massage gun, or both, would help them stick with these pain-management strategies. Researchers enrolled 108 women aged 65+ who reported chronic pain as a barrier to being active. The …

This study compared two types of temporary tubes (stents) placed after surgery to remove kidney or ureteral stones. Researchers tested whether a new silicone stent causes less pain and fewer urinary problems than the standard plastic stent. The trial involved 224 patients who wer…

This small study looked at whether a combination of exercise training and a ketone ester supplement could help people with Parkinson's disease. Researchers wanted to see if this approach could improve muscle strength, endurance, and heart and lung fitness. Twenty participants wit…

This study looked at whether people with alcohol problems who have experienced suicidal thoughts could benefit from a therapy session about the National Suicide Prevention Lifeline. Researchers wanted to understand who uses the crisis line during a suicidal crisis and who doesn't…

This study tested a 6-week video support program designed specifically for Black family members caring for loved ones with Alzheimer's or dementia. The program brought small groups together weekly to learn culturally relevant strategies for managing stress and personal health whi…

This study looked at whether a special type of massage could help reduce shoulder muscle stiffness and improve blood flow in breast cancer survivors with ongoing pain. It also tested if the level of communication between the patient and therapist made the massage more effective. …

This study tested whether a wearable device that delivers gentle electrical stimulation to specific points on the arm and leg could improve stomach symptoms and function in people with diabetic gastroparesis. Forty-one participants used the device or a sham version for 8 weeks, w…

This study tested a program called Mood Lifters, where college students lead weekly group meetings to help their peers manage mental health. The goal was to see if this low-cost, peer-led approach could effectively reduce symptoms of depression and anxiety in undergraduate studen…

This study tested whether a 30-day program of positive activities could help people with chronic low back pain feel and function better. 200 adults scheduled for a standard steroid injection were randomly assigned to either try the 'Positive Piggy Bank' program right away or to w…

This study tested whether an online training program called Work Chat could help autistic adults improve their workplace social skills. Researchers wanted to see if delivering this training completely online was practical and effective. The program aimed to help participants bett…

This study tested whether a wearable light therapy device worn in the morning could help improve mood in women with postpartum depression. Researchers compared a bright light version to a dim placebo light over 5 weeks in 95 new mothers. They measured changes in depression sympto…

This study tested a small, wearable device that delivers mild electrical stimulation through skin patches to reduce abdominal pain in people with chronic pancreatitis. Forty-two participants used the device at home for several weeks to see if it helped manage their pain without m…

This study tested whether an 8-week exercise program was practical and helpful for older adults living in a low-income housing complex. Researchers worked with 27 participants to see if the program could safely increase their weekly physical activity and improve measures like bal…

This small, completed pilot study tested a non-invasive, home-use device called Transcutaneous Electrical Acustimulation (TEA) for treating abdominal pain in people with chronic pancreatitis. The main goal was to check if the study was practical to run and if patients could use t…

This study tested a new, low-cost device called NewGait designed to help stroke survivors improve their walking during at-home rehabilitation. Researchers worked with 20 stroke survivors to get feedback and compare how well the device worked against other similar aids. The goal w…

This study tested a web-based program called 'My Pelvic Plan' to see if it could help women with chronic pelvic pain and endometriosis. The program taught self-management skills to reduce pain interference, lower pain intensity, and boost confidence in handling symptoms. Research…

This small, completed pilot study tested whether a personalized program combining talk therapy, brain training exercises, and lifestyle advice is practical and helpful for people with thinking problems from conditions like brain injury, multiple sclerosis, or mild memory loss. Th…

This study explored whether a non-invasive brain stimulation technique could help reduce the sudden, disabling changes in alertness that are common in people with Lewy body dementia. Researchers tested the approach on 15 participants who were already on stable dementia medication…

This study tested whether offering hospitalized patients a menu of wellness services could improve their hospital experience. Over 600 patients at a Veterans Affairs hospital could choose from items like meditation or music to help them feel better during their stay. Researchers …

This study tested how easy a new mobile app was to use for people with MS. The app guides users through self-administered acupressure techniques aimed at managing pain and fatigue. Ten adults with MS tried the app for six weeks, and researchers interviewed them about their experi…

This small study tested a nerve block injection in the back, called an Erector Spinae Plane Block (ESPB), to see if it could relieve the severe pain of kidney stones. It involved 5 patients in the emergency room who had already received one dose of pain medication. The goal was t…

This study explored whether problems with the inner ear's balance system contribute to walking and balance difficulties in Parkinson's disease. Researchers tested whether a small device that stimulates the inner ear could help improve these symptoms. The study involved 72 partici…

This study tested whether a self-guided phone app called RENEW is practical for people with scleroderma to use. Researchers wanted to see if people with the condition would sign up for the study, stick with it, and use the app. The app provides energy management and resilience-bu…

This small study tested whether a mental training technique called 'operant conditioning' could help improve thigh muscle strength and activation after ACL reconstruction surgery. Researchers worked with 11 adults who had recently undergone ACL surgery, using encouragement and fe…

This study tested whether a gentle electrical stimulation applied to the scalp could help improve memory and thinking in people with mild cognitive impairment or early Alzheimer's disease. Researchers gave different amounts of stimulation to 269 participants while using brain sca…

This study tested a new surgical technique called a Regenerative Peripheral Nerve Interface (RPNI) to prevent and treat severe, chronic nerve pain in people who have had a major leg amputation. The surgery involves implanting the cut nerve end into a small piece of muscle to help…

This small pilot study tested if a 6-week online exercise program, led by an occupational therapist, could help seniors in a housing community become more active. Researchers wanted to see if involving respected community members as advisors would encourage more people to join an…

This small pilot study tested a new program designed to help older adults who have both long-term pain and mild memory problems. Participants received weekly phone calls from a health coach and watched educational videos to learn pain management skills. Researchers wanted to see …

This study tested whether a 7-week program using educational podcasts and sessions with a community health worker could help older adults better manage their chronic pain. Forty participants aged 50+ who experienced daily pain that limited their activities were randomly assigned …

This study aimed to understand how spinal cord stimulation devices affect pain processing in people with chronic pain. Researchers observed 34 patients who were already using these devices as part of their regular medical care. They measured how repeated pain stimuli were perceiv…

This study aimed to find out if 3D printed clear aligners collect more bacteria than the conventional type. Researchers enrolled 30 adults who were not undergoing active orthodontic treatment. They compared the microbial buildup on the aligners and the teeth underneath them, and …

This study tested different ways to help children aged 8-12 stick with a home exercise program. Researchers used a flexible approach, offering personalized calendars, daily text reminders to parents, or coaching sessions to families who struggled with the routine. The goal was to…

This study aimed to find a better way to dose a preventive antibiotic for overweight patients having surgery. Researchers compared the standard weight-based dosing method to a new method based on body composition, measured from a CT scan. They tested which method achieved better …

This study tested whether a short, online art-based training program could reduce stigma and negative attitudes among nurses caring for mothers who use substances and their babies. It involved 99 nurses who completed the training and answered surveys about their attitudes. Resear…

This University of Michigan study aimed to understand how first-year college students develop and cope with stress and mild depression. Researchers followed 120 students, some receiving weekly check-ins and feedback, to identify opportunities for early support before symptoms wor…

This study aimed to find out whether written text or video is a better way to educate patients about cirrhosis, a serious liver condition. Researchers randomly assigned 218 adults with cirrhosis to receive educational materials in one of these two formats. They then measured how …

This study aimed to understand how much fluoride stays in saliva after brushing with regular or prescription toothpaste, and whether adding a fluoride mouthwash makes a difference. Twenty healthy adults from Michigan tried four different combinations of toothpaste and mouthwash. …

This small, completed study aimed to understand how a drug called dupilumab works in people with a chronic, unexplained skin rash. Researchers gave 10 participants injections of dupilumab to see how it changed their immune cells and if it reduced the rash and itching. The main go…

This small study tested whether gentle electrical stimulation of nerves in the leg or genital area could increase blood flow to the vagina. It involved 9 women, including those with sexual dysfunction, some with spinal cord injuries, and some without any dysfunction. The goal was…

This study explored how people with mild memory problems or early Alzheimer's disease understand and emotionally handle learning the results of their brain scans. Researchers educated 152 participants about brain proteins linked to Alzheimer's, then shared their personal scan res…

This study aimed to understand how people with anxiety can learn to control their emotions by seeing real-time pictures of their own brain activity. Researchers used a brain scanner to give 21 participants feedback, comparing a real feedback group to a fake feedback group. The go…

This study tested whether structured meetings between different clinic staff roles (like doctors, nurses, and medical assistants) could improve teamwork and reduce burnout. Over 600 staff members from five family medicine clinics participated in sessions where they discussed what…

This study aimed to understand how daily stress, anxiety, and mood affect blood sugar control in teens and young adults with type 1 diabetes. Researchers tracked 47 participants aged 13-26 using smartphone surveys and continuous glucose monitors to see the connection between feel…

This study aimed to understand why a common type of blood pressure medicine works better for some people than others. Researchers gave the drug enalapril to 21 healthy volunteers to see if differences in a specific liver gene affect how the body activates the medicine. The goal w…

This study tested whether showing AI advice to pharmacists at different times could help them work faster and more accurately when checking medications. Researchers had 68 licensed pharmacists use a computer system to verify mock prescriptions, with some getting AI help during th…

This study aimed to understand why some people with chronic low back pain get better with certain treatments while others do not. Researchers tested four different 8-week treatments—mindfulness therapy, physical therapy, acupressure, and a medication—on nearly 500 participants. T…

This study aimed to understand how the brain processes information at the edge of consciousness during anesthesia. Researchers used brain scans (fMRI) on 36 healthy volunteers while they were given the anesthetic drug propofol. They tested whether a form of ultrasound brain stimu…

This study tested whether a free online course could effectively teach basic first aid skills to laypeople in four African countries. Researchers compared the online training to traditional in-person classes for 658 commercial drivers and other transport providers. The goal was t…

This study tested a new digital app designed to provide education and social support to teenagers at risk of suicide. Researchers enrolled 75 teens and their caregivers to see if the app was easy to use and helpful. The main goal was to gather feedback on the app's design and fea…

This study aimed to gather preliminary information about how a common breast cancer hormone therapy might affect the aging process. Researchers enrolled 94 women, primarily aged 65 and older, who were starting this standard treatment. They collected blood and stool samples and su…

This study tested a new digital vaccine card and mobile app in rural Uganda and urban Kenya to see if it helps more children get their recommended vaccines on time. Researchers enrolled over 3,500 children to see if the digital system improved record-keeping and made it easier fo…

This study aimed to understand what influences how people with chronic pelvic pain think about different treatment options. Researchers asked 30 patients about their past experiences and trusted information sources. They also tested if a free, online self-management program could…

This study aimed to understand if adjustable prosthetic sockets are more comfortable and improve mobility compared to standard sockets. Researchers tested 29 adults with above-knee amputations, having them try both their usual socket and different adjustable designs. They measure…

This study looked at whether showing patients the images taken during their spine injection procedure could improve their satisfaction with care. Researchers worked with 141 adults who received a specific steroid injection for back and leg pain. They measured how satisfied patien…

This study aimed to understand how older adults think about starting or stopping medications, a process called 'deprescribing.' Researchers surveyed 2,400 adults aged 65 and older in the US and Australia, asking them to react to a hypothetical patient scenario. The goal is to use…

This study looked back at medical records and CT scans from 233 people with severe asthma who were taking biologic drugs. Researchers used computer analysis of the scans to see if body composition, like muscle size and quality, could predict who would have fewer asthma attacks or…

This small, completed study observed 30 people with chronic neck or shoulder pain who were referred to physical therapy. Researchers wanted to see if the specific characteristics of a person's pain at the start could predict how well they would respond to physical therapy after t…

This study aimed to understand why some older adults maintain a fast walking speed despite age-related brain and leg changes, while others slow down. Researchers focused on the brain's dopamine system, suspecting it might provide a protective 'resilience.' They enrolled 5 older a…

This study tested whether sending urologists personalized feedback emails would make them more likely to use an online dashboard. The dashboard shows data about avoiding unnecessary stents after kidney stone surgery. Researchers compared personalized emails to generic ones to see…