Breath test may guide IBS-D treatment choices
NCT ID NCT03729271
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether a simple breath test can help predict which people with diarrhea-predominant irritable bowel syndrome (IBS-D) will respond to the drug rifaximin. 148 participants took rifaximin and completed breath tests and surveys. The goal was to see if the breath test could identify those most likely to get relief from abdominal pain and diarrhea.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
rifaximin (Xifaxan)
What this could lead to
If successful, this could help doctors identify which IBS-D patients are most likely to benefit from rifaximin, making treatment more personalized.
What could go wrong
This is a completed Phase 4 study focused on prediction, not a new treatment. The breath test may not reliably predict response, and results may not apply to all IBS-D patients.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Michigan
Ann Arbor, Michigan, 48109, United States