University Of Michigan
Clinical trials sponsored by University Of Michigan, explained in plain language.
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New dental membrane tested to fight implant infections
Disease control ENROLLING_BY_INVITATIONThis study compares two different surgical membranes used during dental surgery to treat peri-implantitis, which is gum disease that develops around dental implants. Researchers will test a new reinforced PTFE mesh against a traditional collagen membrane to see which helps bone a…
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Apr 01, 2026 21:41 UTC
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Can your smartphone help manage your heart failure?
Disease control OngoingThis study is testing a mobile app designed to help people with heart failure better manage their condition. The app tracks health status, vital signs, weight, and medications, and shares this information with doctors. Researchers want to see if using this app helps patients get …
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Apr 01, 2026 21:41 UTC
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New synthetic bone graft tested for better jawbone healing
Disease control ENROLLING_BY_INVITATIONThis study aims to see if a synthetic bone graft material works better than natural options for preserving jawbone after tooth extraction. Researchers will compare three types of bone grafts in 45 patients who need a tooth removed and plan to get a dental implant later. The goal …
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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Can a smartphone app curb teen violence? AI therapy study aims to find out
Disease control OngoingThis study is testing two versions of a remote therapy program delivered via smartphone to help teens and young adults (ages 14-24) who were treated in the emergency room for a violent injury. The goal is to reduce their future involvement in violence, aggression, and related ris…
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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One-Visit dental crowns put to the test in 5-Year study
Disease control OngoingThis study is testing new, stronger ceramic dental crowns that can be made and placed in a single appointment. Researchers will follow 48 patients with damaged or decayed back teeth for five years to see how well these crowns hold up and whether they cause tooth sensitivity. The …
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Could cherry juice calm Post-Surgery hearts?
Disease control OngoingThis study is testing whether a tart cherry concentrate drink can help prevent irregular heartbeats (atrial fibrillation) that sometimes occur after heart surgery. It will involve 50 patients aged 50-79 who are having elective mitral valve repair surgery. Researchers will measure…
Phase: PHASE1, PHASE2 • Sponsor: University of Michigan • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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Tiny tube in nose helps Weak-Muscled kids sleep and breathe
Disease control ENROLLING_BY_INVITATIONThis study is following children with weak muscles (hypotonia) who have trouble breathing during sleep due to a blocked airway. Researchers are checking if a small, flexible tube placed in the nose helps keep the airway open over the long term, improves sleep quality, and is comf…
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Video calls fight frailty in rare heart condition
Disease control OngoingThis study is testing whether a structured home exercise program, delivered through video calls, can help adults with a rare heart condition called Fontan circulation become less frail and improve their strength and endurance. The program aims to make exercise training more acces…
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Diet showdown: which eating plan works best for PCOS?
Disease control OngoingThis study is comparing two popular diets—the DASH diet and a very low-carbohydrate diet—to see which one works better for improving blood sugar control and helping with weight loss in adults with polycystic ovary syndrome (PCOS). About 223 participants will follow one of these e…
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Can fellow patients help black men beat diabetes?
Disease control OngoingThis study is testing whether adding peer support helps Black men better manage type 2 diabetes. All 48 participants receive standard diabetes education. Half also get 6 months of monthly support sessions led by trained Black men who also have diabetes, followed by 6 months of gr…
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Doctors test four ways to make gum surgery less painful
Disease control ENROLLING_BY_INVITATIONThis study compares four different gum surgery techniques to see which one works best for healing and causes the least pain. Researchers will test these methods on 48 patients who need gum tissue grafts for recession. They'll track healing progress and patient comfort over three …
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Mar 23, 2026 15:18 UTC
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Personal coach trial aims to help seniors tackle obesity
Disease control OngoingThis small pilot study is testing whether adding a personal coach helps older adults with obesity stick to their clinic's weight loss plan. The coach helps patients attend appointments like physical therapy and nutrition counseling, and connect to community resources. Researchers…
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Mar 23, 2026 15:17 UTC
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Can video calls help people cut back on drinking?
Disease control OngoingThis study is testing whether a telehealth program delivered by video or phone can help people with alcohol use disorder start treatment and reduce their drinking. Researchers are comparing this remote program to standard care to see which approach works better. The goal is to fi…
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Mar 18, 2026 14:40 UTC
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Can a good Night's sleep stop another stroke?
Disease control OngoingThis large study is testing if treating sleep apnea soon after a stroke can help people recover better and prevent future health crises. Over 3,000 recent stroke patients are being randomly assigned to either receive standard care or standard care plus treatment for their sleep a…
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Mar 16, 2026 15:24 UTC
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Can group support boost heart health in underserved communities?
Disease control OngoingThis study is testing a community program called Health Impact 360 to see if it improves heart health, reduces stress, and increases social support for adults in marginalized neighborhoods. Over 300 participants will attend group sessions and track their activity for 16 weeks, co…
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Mar 13, 2026 15:05 UTC
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Quick bedside test aims to speed up constipation diagnosis
Diagnosis ENROLLING_BY_INVITATIONThis study is testing whether using a simple bedside device during routine doctor visits can help quickly evaluate chronic constipation. Researchers want to see if having this device available makes doctors more likely to order the right tests and treatments. The study involves 1…
Phase: NA • Sponsor: University of Michigan • Aim: Diagnosis
Last updated Mar 30, 2026 14:32 UTC
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Text messages and counseling aim to save teens after suicide crisis
Prevention OngoingThis study tests different combinations of counseling and text message support to prevent suicidal behavior in teenagers after they leave psychiatric hospitalization. Researchers are comparing safety planning sessions with and without follow-up text messages, then adding extra su…
Phase: NA • Sponsor: University of Michigan • Aim: Prevention
Last updated Apr 01, 2026 14:42 UTC
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Can school coaches stop youth violence before it starts?
Prevention OngoingThis study is looking at whether a school program called Pathways to Potential helps prevent youth violence. The program places 'success coaches' in Michigan public schools to identify and help with family needs like transportation or unemployment, which can affect school attenda…
Sponsor: University of Michigan • Aim: Prevention
Last updated Apr 01, 2026 14:42 UTC
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Can a fun afterschool program fight childhood inactivity?
Prevention OngoingThis study is testing a special afterschool program called CHAMP-ASP to see if it helps young children become more physically active and improve their health. About 264 children, ages 5 to 8, will participate in the program for 35 minutes a day, 3-4 days a week, for 19 weeks. Res…
Phase: NA • Sponsor: University of Michigan • Aim: Prevention
Last updated Mar 30, 2026 14:30 UTC
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Can your diet stop cancer? new study tests three eating plans for High-Risk adults
Prevention OngoingThis study is testing three different healthy eating approaches to see which best helps overweight adults at risk for colorectal cancer improve their diet and potentially lose weight. 240 participants will follow one of the eating plans for 12 months, with some groups getting ext…
Phase: NA • Sponsor: University of Michigan • Aim: Prevention
Last updated Mar 23, 2026 15:17 UTC
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Could a buddy and grocery money stop diabetes?
Prevention OngoingThis study is testing if adding two extra supports helps people stick with a proven diabetes prevention program. Low-income adults with prediabetes will either join the standard program or the program plus a peer buddy and chances to earn healthy food vouchers. Researchers will s…
Phase: NA • Sponsor: University of Michigan • Aim: Prevention
Last updated Mar 23, 2026 15:16 UTC
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Virtual coach aims to help autistic youth land and keep jobs
Symptom relief ENROLLING_BY_INVITATIONThis study is testing a new computer training program designed to help young adults with autism spectrum disorder (ASD) improve the social skills needed for work. The program uses interactive lessons and simulated conversations with virtual customers and bosses to practice workpl…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Apr 01, 2026 21:41 UTC
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Better sleep could mean less drinking: new therapy study
Symptom relief OngoingThis study is testing two different talk therapies for insomnia in people who are also being treated for alcohol use disorder. Researchers want to see if improving sleep can help people drink less and feel less tired during the day. The study involves 134 participants who have bo…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Apr 01, 2026 21:40 UTC
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Could a simple tracker ease the burden on dementia caregivers?
Symptom relief TerminatedThis study aimed to test a tracking device called Care Companion, designed to help family caregivers monitor loved ones with dementia who are at risk of wandering away. The research planned to first check if the system was practical to use, then measure if it actually reduced car…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Apr 01, 2026 14:43 UTC
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Phone calls and podcasts fight loneliness and pain in seniors
Symptom relief OngoingThis study tests a community health worker program called RESET, designed to help older adults in Detroit manage symptoms like depression, anxiety, chronic pain, and loneliness. Over 450 participants will join group phone calls, listen to podcasts, and use activity trackers to bu…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Mar 31, 2026 12:11 UTC
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Can yoga coaching ease the constant pain of lupus?
Symptom relief OngoingThis small study is testing whether a personalized, virtual yoga coaching program is a practical way to help people with lupus manage their chronic pain. Researchers are working with 15 participants to see if they can successfully recruit people and have them complete the 13-week…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Mar 31, 2026 12:10 UTC
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Classroom program aims to empower Kids' mental health
Symptom relief OngoingThis study is testing a school-based program designed to help children aged 6-12 manage symptoms of anxiety and depression. It teaches coping and emotion regulation skills directly in the classroom, aiming to reach kids who might not have access to traditional mental health care.…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Mar 30, 2026 14:30 UTC
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Can a website ease the agony of chronic pancreatitis?
Symptom relief OngoingThis study is testing whether a 12-week online self-management program can help people with painful chronic pancreatitis. Thirty participants will use a website called PainGuide, which provides weekly lessons and tailored advice based on their symptoms. The main goal is to see if…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Mar 30, 2026 14:28 UTC
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Seaweed minerals tested as potential bad breath fix
Symptom relief OngoingThis study is testing whether a natural mineral supplement called Aquamin, which comes from red seaweed, can help reduce bad breath when taken daily for 90 days. It involves 15 adults who report having halitosis. Researchers will measure changes using a questionnaire about how ba…
Phase: PHASE2 • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Mar 27, 2026 12:40 UTC
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Neighbors helping neighbors fight chronic pain
Symptom relief OngoingThis study tests whether community health workers can effectively teach pain management strategies to older adults with chronic pain. Over 400 primarily African American older adults will receive 7 weeks of phone sessions and mobile tools to learn coping skills, compared to a gro…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Mar 27, 2026 12:39 UTC
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Can simple social connections and therapy ease the pain of loneliness?
Symptom relief OngoingThis pilot study is testing whether two different approaches—'social prescribing' (connecting people to community activities) and brief cognitive therapy—are practical and acceptable ways to help adults struggling with loneliness and suicidal thoughts. The University of Michigan …
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Mar 27, 2026 12:39 UTC
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Virtual club aims to strengthen frail hearts in teens
Symptom relief OngoingThis study is testing a virtual wellness program for teenagers with a complex heart condition called Fontan physiology. The program combines group education with personalized home exercises to see if it can reduce frailty, increase physical activity, and improve quality of life. …
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Mar 27, 2026 12:39 UTC
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Can a virtual coach help autistic youth land their first job?
Symptom relief ENROLLING_BY_INVITATIONThis study is testing whether an online job interview training program can help young adults with autism improve their interview skills and get jobs. About 200 participants will either use the virtual training or continue with their usual services. Researchers will track who gets…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Mar 27, 2026 12:38 UTC
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Remote mindset training could ease debilitating migraine suffering
Symptom relief OngoingThis study is testing whether two brief, remote behavioral programs can help adults with chronic migraine reduce their headache-related disability and symptom severity. 300 participants will be randomly assigned to either an 'Empowered Relief' program, a health education program,…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Mar 02, 2026 15:22 UTC
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Groundbreaking study reveals hidden dementia crisis in aging mexican american population
Knowledge-focused OngoingThis research aims to understand how common dementia is among older Mexican Americans compared to non-Hispanic whites in Texas. Researchers are visiting homes to track participants' cognitive health over time and examine what factors might contribute to differences between groups…
Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Apr 01, 2026 21:41 UTC
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Researchers probe link between straining and painful hemorrhoids
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to understand how straining during bowel movements affects hemorrhoid symptoms. Researchers will use a special device to test pelvic floor function in 100 participants with bleeding hemorrhoids. The goal is to identify which patients might benefit from treatments …
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Apr 01, 2026 21:41 UTC
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Can smart PE classes make kids healthier and happier?
Knowledge-focused ENROLLING_BY_INVITATIONThis study is testing whether using heart rate monitors and a special system during physical education (PE) classes helps improve children's fitness, physical activity, social skills, and mental well-being. It involves about 970 students in 4th through 7th grades from 17 Michigan…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Apr 01, 2026 21:40 UTC
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The hidden cost of liver disease: study tracks financial strain on families
Knowledge-focused OngoingThis study aims to understand the financial burden and stress experienced by patients with liver cirrhosis and their family caregivers. It follows 52 participants and their caregivers for 72 weeks, tracking out-of-pocket medical costs, lost work productivity, and overall financia…
Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Does knowing your Alzheimer's risk change your life?
Knowledge-focused OngoingThis study looks at how Black and White patients with mild memory problems change their health habits, future planning, and research participation after learning about their Alzheimer's risk through brain scan results. Researchers want to understand if this information helps peop…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC
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Can a website help people with health issues pick safer birth control?
Knowledge-focused ENROLLING_BY_INVITATIONThis study is testing whether a web-based tool called 'My Health, My Choice' helps people with chronic health conditions (like diabetes or high blood pressure) understand and choose birth control options that are safer for their specific health situation. Researchers will compare…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:27 UTC
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Can a simple meeting reduce nurse burnout? ICU study investigates
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to understand if having ICU nurses meet with their former patients after hospital discharge affects the nurses' job satisfaction and feelings of burnout. It involves 10 former ICU patients and 20 of their former nurses, with half the nurses randomly selected to ha…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:40 UTC
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New tool helps kidney patients navigate family planning decisions
Knowledge-focused OngoingThis study is testing an educational tool designed to help people with chronic kidney disease make informed decisions about pregnancy and contraception. Kidney doctors will use this tool with 60 patients to see if it helps them feel better prepared for these important health choi…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Scientists scan spines to solve mystery of brain fluid flow
Knowledge-focused ENROLLING_BY_INVITATIONThis study uses special MRI scans to understand how moving your neck affects the flow of fluid around your brain and spinal cord. It involves 50 people, including healthy volunteers and those with a condition called Chiari malformation. The goal is to gather information that migh…
Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC
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Researchers probe hidden breathing dangers for spina bifida babies
Knowledge-focused OngoingThis study aims to understand if sleep-related breathing problems are different for infants with severe spina bifida who had surgery before birth versus after birth. It will also check if these breathing issues are linked to how a child's thinking and movement skills develop by a…
Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:18 UTC
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Wrist-Worn device tested for future help with chemotherapy side effects
Knowledge-focused TerminatedThis early study aimed to check if a new wrist-worn device is safe and easy to use. It planned to test the device on healthy volunteers to gather information before future studies with cancer patients. The main goals were to see if people could use the device properly and to moni…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Mar 18, 2026 14:41 UTC
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Brain scans unlock Parkinson's walking mystery
Knowledge-focused OngoingThis study aims to understand how changes in specific brain chemicals over time relate to walking difficulties, balance problems, and cognitive changes in people with Parkinson's disease. Researchers will use special brain scans (PET imaging) at the start of the study and again t…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Mar 17, 2026 12:55 UTC
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Survey asks seniors: when should you stop your aspirin?
Knowledge-focused ENROLLING_BY_INVITATIONThis is an online survey study to understand how adults aged 65 and older think about stopping aspirin. Researchers will ask 2,400 participants from the US and Australia for their opinions on a hypothetical patient scenario. The goal is to learn how to improve conversations betwe…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Mar 02, 2026 15:29 UTC
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Can a Crown's hidden shape save your implant?
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to find out if the shape of a dental implant crown under the gumline affects the health of the surrounding bone and gum tissue. Researchers will compare two different crown shapes in 30 participants who already have a dental implant. They will monitor changes in b…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Feb 23, 2026 14:56 UTC