University Of Michigan

This study tests a mobile app that helps heart failure patients track their symptoms, vital signs, and weight. The app shares this information with doctors to improve medication use and quality of life. About 130 adults with heart failure and reduced pumping function will partici…

This study tests different ways to help people drink less alcohol before and after major elective surgery. The goal is to improve surgical recovery and long-term health. About 440 adults scheduled for non-cancer surgery are taking part. Researchers will track how much alcohol par…

This study compares two standard methods for treating severe traumatic brain injury in the ICU. One method monitors only brain pressure, while the other also tracks brain oxygen levels. Researchers want to see if adding oxygen monitoring helps improve recovery and survival. About…

This study looks at whether treating obstructive sleep apnea with a CPAP machine, starting soon after a stroke, can lower the chance of having another stroke, a heart attack, or dying within 6 months. Over 3,000 people who had a stroke are taking part. The goal is to see if sleep…

This study compares two diets—the DASH diet and a very low-carb diet—to see which one better helps adults with polycystic ovary syndrome (PCOS) control blood sugar and lose weight. About 223 participants will follow their assigned diet for 12 months. The goal is to find a practic…

This study tests a program called Health Impact 360 to improve heart health, mental well-being, and social support in adults from marginalized communities. About 328 participants will join group sessions, track their physical activity, and have their health measured at the start …

This study tests whether a lab-made bone graft material (carbonate apatite) helps preserve the jawbone after tooth extraction better than grafts from human or cow bone. About 45 adults needing a tooth pulled will receive one of the three graft types. Researchers will measure bone…

This study looks at how well a special nasal tube works over time for children with weak muscle tone (hypotonia) who have obstructive sleep apnea. About 40 children who already used the device in earlier studies will continue using it. Researchers will check if it keeps the airwa…

This study tests whether monthly support sessions led by trained Black men with diabetes can help other Black men better manage their type 2 diabetes. All participants receive diabetes education, and half also get 6 months of peer support followed by ongoing group activities. The…

This study tests a new type of mesh (RPM) against a standard collagen membrane for surgery to repair bone and gum damage around dental implants. About 32 adults with peri-implantitis will be treated and followed to see which material leads to better healing. The goal is to contro…

This study looks at whether tart cherry concentrate can lower the chance of an irregular heartbeat (atrial fibrillation) after mitral valve surgery. About 50 adults aged 50-79 who are in normal rhythm before surgery will take the concentrate. Researchers will track hospital stay …

This study tests a new high-strength ceramic material for dental crowns that can be made in one appointment using a computer, so you don't need a temporary crown or a second visit. About 48 adults with a decayed, fractured, or failing filling in a back tooth will get the crown an…

This study tests whether remote programs (via Zoom, FaceTime, or phone) can help people manage their alcohol use and improve well-being. About 300 adults with alcohol use disorder will be randomly assigned to either a telehealth group program or enhanced usual care. The goal is t…

This study looks at how the part of a dental crown that sits below the gum line affects the health of the gum and bone around dental implants. Researchers will measure bone loss, gum thickness, and gum height in 30 adults who already have an implant ready for a crown. The goal is…

This study compares two versions of a remote behavioral therapy for teens and young adults (ages 14-24) who came to the ER for a violent injury. One version is standard; the other uses artificial intelligence to adapt the therapy in real time. The goal is to see which approach be…

This study looks at three different eating plans to see which one helps overweight adults at risk for colorectal cancer eat healthier and lose weight. About 240 people with a family or personal history of colorectal cancer or polyps will follow one of the plans for 12 months. The…

This study tests whether adding a support buddy and healthy food vouchers to a standard diabetes prevention program helps low-income adults with prediabetes stick with healthy habits and lower their risk of developing diabetes. About 142 participants will be split into two groups…

This study tests a virtual, at-home exercise program for adults with Fontan heart physiology, a condition where the heart has a single pumping chamber. The goal is to see if the program can reduce frailty and improve exercise capacity. About 53 participants will use a telemedicin…

This study tests a program called RESET, led by community health workers, to help older adults in Detroit improve their physical and mental well-being. About 456 African American adults aged 50 and older with symptoms like depression, anxiety, chronic pain, or loneliness will tak…

This study tests whether brief behavioral programs can reduce disability and symptoms in adults with chronic migraine. 300 participants will be randomly assigned to one of four remote interventions. The goal is to see if changing behaviors can improve daily life and reduce migrai…

This study tests whether Aquamin®, a natural multi-mineral supplement from red marine algae, can reduce bad breath (halitosis). Fifteen adults with self-reported halitosis will take the supplement for 90 days and report changes in their breath-related quality of life. The goal is…

This study tests two treatments for loneliness and suicidal thoughts: Social Prescribing (connecting people with community activities) and Brief Cognitive Therapy (changing unhelpful thinking patterns). Researchers want to see if these treatments are practical and well-liked by 6…

This study tests a program called Kids' Empowerment Program (KEP) in schools to help children ages 6 to 12 reduce symptoms of anxiety and depression. About 120 children will take part, with some starting the program right away and others later. The goal is to give children tools …

This study tests whether an internet-based job interview training program helps autistic young adults improve their interview skills and find jobs. About 200 participants will either use the Virtual Interview Training or continue with their usual services. The goal is to see if t…

This study tests an 8-week online group program designed to help people with scleroderma improve their thinking skills and overall well-being. Researchers will compare participants who take the program right away to those on a waitlist. The goal is to see if the program boosts me…

This study is testing whether a tailored yoga coaching program can help reduce chronic pain in people with lupus (SLE). Researchers are enrolling 15 adults with stable lupus medications and ongoing pain to see if the program is practical and helpful. The goal is to improve pain m…

This study tests whether a virtual reality (VR) program can help manage pain in people with inflammatory bowel disease (IBD). About 40 adults with IBD and abdominal pain will use a VR headset at home for 4 weeks. The goal is to see if the program is easy to use and helps reduce p…

This study looks at whether giving caffeine to adults aged 70 and older after major surgery can reduce their risk of postoperative delirium—a state of sudden confusion that can slow recovery. About 250 participants are being followed to see if caffeine helps them think more clear…

This study looks at whether adding a patient coach helps older adults with obesity stick to their weight and health plan. About 19 people will take part, and researchers will track things like attending appointments and reaching diet and exercise goals. The goal is to see if extr…

This study tests whether a cream called imiquimod can shrink sebaceous hyperplasia, which are harmless, enlarged oil glands that look like small bumps on the face. About 40 adults with bumps on both sides of their face will use the cream for 8 weeks. Researchers will check if the…

This study is testing a virtual wellness program for teenagers with Fontan physiology, a complex heart condition. The program combines group education with personalized home exercise plans to see if it can improve resilience, reduce frailty, and increase daily activity. Researche…

This study looks at how emotions, attachment, and feeding work together in mothers and babies during the first year of life. Researchers want to understand why some babies gain weight quickly, which can lead to obesity later. About 250 mother-infant pairs will be followed to meas…

This study looks at how social and financial challenges—like income, education, and out-of-pocket costs—affect people with cirrhosis and their caregivers. Researchers will ask participants and their caregivers about financial stress and healthcare use. The goal is to better under…

This study looks at whether adding technology (like heart rate monitors) to physical education classes helps students get more active, improve their fitness, and feel better mentally. About 970 students in grades 4-7 will take part. Researchers will measure their activity levels,…

This study looks at whether a special bedside device can help doctors evaluate chronic constipation during a routine office visit. About 109 adults with chronic constipation will use the device and answer a survey. The goal is to see if this approach leads to more appropriate tes…

This small pilot study tested whether a 6-week remote occupational therapy program could help older adults living in affordable senior housing become more physically active. The program used respected residents to encourage participation and included one-on-one and group sessions…

This study tests different ways to remove the outer layer of gum tissue during gum graft surgery. Researchers want to see which method leaves less leftover tissue, helps the donor site heal better, and causes less pain. About 48 adults needing gum surgery will take part to find t…

This study looks at breathing during sleep in infants with myelomeningocele, a severe form of spina bifida. Researchers want to see if the risk of sleep breathing problems differs between babies who had surgery before birth versus after birth. They will also check how these breat…

This study looks at why straining during bowel movements may cause hemorrhoids to bleed. Researchers will use a special device to test how well the rectum can empty, which may help identify people who could benefit from treatments targeting pelvic floor muscle problems. About 100…

This study looks at whether counseling sessions delivered by video (telehealth) are practical and well-liked by people with substance use disorder who are not currently getting treatment. About 50 participants will complete surveys and attend counseling sessions. The goal is to i…

This study looks at whether a special afterschool program called CHAMP can help children ages 5 to 8 be more physically active and improve their motor skills. About 264 kids will take part in the program or a regular afterschool activity for 19 weeks. Researchers will measure cha…

This study aimed to test a tracking system called Care Companion for family caregivers of people with dementia who are at risk of wandering. It was designed in two stages: first to see if the system was easy to use, and second to measure its effect on caregiver well-being. Howeve…

This study tests a new educational tool to help people with chronic kidney disease (CKD) make informed decisions about pregnancy and contraception. About 70 participants will use the tool and then answer a survey to see how prepared they feel to make those decisions. The goal is …

This study uses MRI scans to measure how different neck positions change the flow of cerebrospinal fluid (the fluid around the brain and spinal cord) in people with Chiari malformations and healthy volunteers. Researchers aim to understand which neck positions affect fluid flow m…

This study looks at a Michigan program called Pathways to Potential (P2P) that places social workers in schools to connect students and their families with community resources for needs like transportation or jobs. Researchers want to see if this program reduces youth violence, c…

This study looks at how 100 Black and White patients with mild memory problems change their health habits, planning, and research involvement after learning their Alzheimer's risk from brain scans. Researchers want to see if knowing about amyloid and tau buildup leads to positive…

This study tested a wearable device (Watch-TEA) that uses mild electrical stimulation on the skin. It was designed for healthy volunteers to check if the device is safe and easy to use. The goal is to later help cancer patients manage symptoms caused by chemotherapy. The study wa…

This study follows 125 people with Parkinson's disease or related conditions over two years. Researchers use special brain scans to measure changes in a chemical called acetylcholine, which is linked to movement and attention. The goal is to understand why some patients develop w…

This study looks at what happens when ICU nurses meet with patients they once cared for, after the patients leave the hospital. Researchers want to see if these meetings improve nurses' job fulfillment and reduce burnout. The study involves 10 patients and 20 nurses, with half th…

This study follows about 400 children (ages 5-7) and their parents to see how eating behaviors learned in infancy affect diet, growth, and behavior later in childhood. Researchers measure body mass index and track nutrient intake using food diaries. The goal is to understand earl…

This study tests new technology-driven programs to help people manage their alcohol use and overall well-being. Researchers are looking at whether these virtual programs can improve access to treatment and help people start and stick with therapy. The study involves 362 adults wi…

This study tests a free web tool called My Health, My Choice that helps people with health conditions (like diabetes or high blood pressure) understand their birth control options. About 795 participants will either use the tool before a clinic visit or receive usual care. Resear…

This study looks at how common dementia and memory problems are in Mexican American and non-Hispanic white adults aged 65 and older. Researchers will track changes in thinking skills over time and explore what support patients and their caregivers need. The goal is to find better…