New mesh could save failing dental implants

NCT ID NCT06153212

ENROLLING_BY_INVITATION Disease control Sponsor: University of Michigan Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 02, 2026 · Updated 2 times

Summary

This study tests a new reinforced PTFE mesh (RPM) against a standard collagen membrane for treating peri-implantitis, a gum infection around dental implants. Thirty-two adults with at least one infected implant will receive surgery to clean the implant, fill the bone defect with graft, and cover it with one of the two membranes. The goal is to see which material better restores bone and gum health around the implant.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: reinforced PTFE mesh (RPM) and collagen membrane with bone grafting
What this could lead to: If successful, this could provide a better surgical option to treat gum disease around dental implants, potentially saving implants that might otherwise be lost.
What could go wrong: This is a small early-stage trial with only 32 participants, so results may not apply to everyone. The new mesh might not heal better than the standard collagen membrane, and surgery carries risks like infection or implant failure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PERI IMPLANTITIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Peri-Implantitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERI IMPLANTITIS

Contacts and locations

Locations

University of Michigan School of Dentistry

Ann Arbor, Michigan, 48109, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.