Could an extra dose of antibiotics during appendix surgery cut infection risk?
NCT ID NCT06860802
First seen Jun 24, 2026 · Last updated Aug 14, 2026 · Updated 3 times
Summary
This study looks at whether giving an extra dose of the antibiotic cefoxitin during appendix removal surgery can better prevent infections compared to the usual single dose before surgery. Researchers will measure antibiotic levels in blood, fat, and appendix tissue from 46 participants. The goal is to find the best dosing strategy to reduce infection, side effects, and antibiotic resistance.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- cefoxitin
- What this could lead to
- If successful, this could lead to better dosing guidelines for antibiotics during appendix surgery, reducing infections and side effects.
- What could go wrong
- This is a small, early-phase study with only 46 participants. The new dosing method may not prove better than the current standard, and results may not apply to all patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Michigan Medicine
Ann Arbor, Michigan, 48108, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.