PAIN, POSTOPERATIVE

This small, early study aimed to find a safe and tolerable dose of ketamine for women experiencing pain and depression after cesarean delivery. Researchers tested different infusion doses on 12 postpartum women to see which caused the fewest unacceptable side effects like dizzine…

This study tested whether applying a gauze dressing soaked with heparin, a common medication, could help prevent thick, raised scars and reduce pain at the site where skin is taken for grafts. In 400 patients, researchers compared a standard dressing on one skin donor site to a h…

This study aimed to find the most effective method for managing pain after minimally invasive chest surgery. Researchers compared three different types of nerve blocks given before surgery to 155 adult patients. The goal was to determine which technique provided the best pain con…

This study tested whether leaving a surgical wound uncovered after the first two days is as safe as changing the bandage every two days. Over 1,100 patients who had surgery for gastrointestinal cancer were randomly assigned to either skip dressing changes or get routine changes. …

This study tested whether applying gentle pressure to specific points on the ear (auricular acupressure) could help reduce pain after a cesarean section. Seventy women who had a C-section were randomly assigned to receive either real acupressure with small seeds or a sham treatme…

This study compared two different nerve-block techniques for controlling pain after hip fracture surgery. Researchers tested whether a newer combination nerve block (PENG + LFCN) works better than a standard nerve block (S-FICB) for pain relief and helping patients regain leg mov…

This study tested two different anesthesia approaches for people having major surgery. One approach used a combination of several non-opioid medications along with opioids, while the other used mainly opioids. Researchers wanted to see which method led to better patient recovery,…

This study tested a new pain medication called NTM-001 for people recovering from bunion surgery. It involved 341 adults and compared the new drug's pain relief to both a placebo (inactive treatment) and morphine over 24 hours. The goal was to see if NTM-001 works as well as a st…

This study looked at two different methods of numbing nerves to control pain after total knee replacement surgery. Researchers observed 90 patients to see which method better reduced pain and helped patients get up and walk sooner after their operation. The goal was to find which…

This study tested whether watching short clips from classic Turkish comedy films could help reduce pain and increase comfort for people recovering from a liver transplant. Researchers compared 120 patients who either watched the comedy clips or received standard care after their …

This study tested whether freezing nerves during robotic lung surgery helps reduce pain afterward. Researchers compared the new freezing technique to standard pain care in 33 patients. The goal was to see if it lowered pain scores and reduced the need for opioid painkillers durin…

This study observed 60 patients after knee replacement surgery to compare two different nerve block combinations used for pain relief. Doctors watched which method—one targeting the back of the knee versus one targeting the side—provided better pain control and reduced opioid use…

This small pilot study tested whether freezing specific chest nerves (cryoablation) during minimally invasive mitral valve surgery could help manage pain afterward. The goal was to see if this technique reduced patients' need for strong opioid painkillers and lowered their pain s…

This study tested two different painkiller combinations delivered through a small tube placed near the spine to manage pain after minimally invasive lung surgery. Researchers compared a standard local anesthetic against that same anesthetic mixed with a strong opioid pain medicat…

This study compared two pain relief approaches for adults recovering from nose surgery. Researchers tested whether a combination of acetaminophen and ibuprofen worked as well as acetaminophen with the opioid hydrocodone over five days. The goal was to find effective pain manageme…

This study tested whether providing education about pain and a pre-surgery check-up could help reduce anxiety, stress, and pain for women undergoing a planned hysterectomy. Researchers worked with 62 women having this surgery at a hospital in Mexico. They compared outcomes betwee…

This study compared two methods of pain control for patients having total hip replacement surgery. Researchers tested whether a specific back injection (ESPB) helps patients walk sooner after surgery compared to a small dose of morphine in the spine. The study involved 70 adults …

This study tested whether two simple mind-body techniques—breathing yoga and progressive muscle relaxation—could help people recover after a liver transplant. Researchers worked with 125 transplant recipients to see if these daily practices could reduce their pain, breathing prob…

This study tested whether a type of talk therapy called cognitive behavioral therapy (CBT) could help reduce long-term pain after surgery for a broken arm or leg. Over 1,000 adults who had surgery for a fracture received either CBT or standard care. The goal was to see if changin…

This study tested different ways to clean root canals during dental treatment to see which method causes the least pain afterward. Researchers followed 80 healthy adults for one week after their root canal procedure, tracking their pain levels. The goal was to find the cleaning a…

This study aimed to find out which of two commonly used numbing medicines works better for patients recovering from jaw surgery. Researchers compared lidocaine, which works quickly but wears off faster, to bupivacaine, which takes longer to start but lasts much longer. They measu…

This study tested if using a longer-acting opioid (methadone) during anesthesia for outpatient surgery leads to better pain relief and reduces the number of opioid pills patients need to take at home after their procedure. It involved 907 adults having surgery with an expected ho…

This study tested a new type of nerve block injection to see if it could reduce pain and the need for strong opioid painkillers after weight loss surgery. Researchers compared the new injection, given during surgery, to standard pain control methods alone. The main goal was to se…

This study tested whether a new eye drop called OCS-01 could reduce pain and inflammation after cataract surgery. Researchers compared two different dosing schedules (once or twice daily) against a placebo drop in 153 patients. The goal was to find the best way to help patients r…

This study tested if giving a long-acting numbing medicine before making the chest incision for heart surgery helps reduce pain afterward. Researchers compared this approach to a placebo in 70 patients to see if it lowered pain scores and reduced the need for strong opioid painki…

This study compared two methods of numbing nerves to control pain after shoulder surgery. Researchers tested a new combination of nerve blocks against the standard method to see if it provided equal pain relief while avoiding a risky side effect that can temporarily paralyze the …

This study compared two different approaches to managing pain during and after gallbladder removal surgery. Researchers tested whether using a combination of non-opioid medications could lead to better recovery than traditional opioid-based pain relief. The study involved 50 adul…

This study tested whether wearing glasses with green or blue lenses could help reduce pain and nausea after kidney donation surgery, offering a potential drug-free option. It involved 48 kidney donors who were asked to wear the glasses for at least 8 hours a day after their opera…

This study tested whether injecting a local anesthetic (ropivacaine) during breast cancer surgery could prevent long-term pain in the breast area. It involved 260 women who had surgery for breast cancer. Researchers compared the anesthetic injection to a placebo to see which grou…

This study looked at whether specific nerve block injections given before surgery could better control pain after a minimally invasive heart bypass operation. Researchers reviewed the medical records of 88 adults who had this surgery, comparing those who received the blocks to th…

This study tested whether watching comedy videos could help patients feel better after a common kidney stone procedure. Researchers compared 110 patients who either watched funny videos or received no special intervention. The goal was to see if laughter could reduce post-surgery…

This study tested whether adding acupuncture during gallbladder removal surgery helps prevent nausea and vomiting afterward. Researchers compared patients who received standard anti-nausea medications alone versus those who also received acupuncture at specific points during thei…

This study tested if a specific way of giving a numbing nerve block could reduce severe 'rebound pain' that sometimes hits patients after shoulder surgery wears off. Researchers compared two injection techniques in 85 adults having arthroscopic shoulder surgery. The goal was to s…

This study tested whether warming and wetting the carbon dioxide gas used to inflate the abdomen during keyhole womb surgery could help prevent patients from getting too cold during the operation. It also tested if adding a local painkiller to this gas could reduce pain after sur…

This study compared two medications, ketamine and lidocaine, to see which one works better for pain after keyhole gallbladder removal surgery. 76 patients were randomly assigned to receive one of the drugs during their operation. Researchers measured their pain levels for 24 hour…

This study tested whether simple, non-drug methods could reduce the pain and anxiety patients feel when a chest tube is removed after heart bypass surgery. Researchers compared standard care to using a vibration device and using vibration plus a cold pack during the removal proce…

This study tested whether injecting local anesthetic during laparoscopic fibroid removal surgery could reduce pain afterward. Researchers compared three approaches in 207 women: standard pain medication alone, medication plus injections at incision sites, and medication plus inje…

This study tested if giving a single dose of the medication pregabalin right before kidney stone surgery could help control pain afterward. The goal was to see if this approach could reduce how much opioid pain medication patients needed to take. About 118 adults having this spec…

This study compared two different nerve block techniques for managing pain after shoulder surgery. Researchers tested whether a newer block that spares the diaphragm muscle works as well as a traditional block for pain control. The study involved 60 patients having arthroscopic s…

This study tested whether a virtual reality (VR) program could help children and teenagers manage pain after surgery. Researchers first developed a training and treatment plan using the VR technology. Then, they tested if using this plan was practical and if it helped reduce pati…

This study tested whether taking melatonin (a natural sleep hormone) for three nights before wisdom tooth surgery could help reduce pain and the need for strong painkillers afterward. Sixty young adults having wisdom teeth removed received either melatonin or a placebo pill befor…

This study tested whether listening to music could help reduce pain and increase comfort for patients recovering from laparoscopic abdominal surgery. Researchers compared 120 patients in Turkey and Iran, with one group listening to 20 minutes of music after surgery while the othe…

This study tested whether adding a drug called hyaluronidase to a standard pain-blocking injection could improve pain relief after a cesarean section. Researchers compared two different doses of hyaluronidase in 114 women who had elective C-sections. The goal was to see if the dr…

This study tested whether adding a small dose of morphine to the standard spinal anesthetic (bupivacaine) provides better and longer-lasting pain relief after hernia repair surgery. Researchers compared the two approaches in 50 adults to see which one delayed the need for additio…

This study tested whether a short mindfulness program, delivered through a popular meditation app called Headspace, could help reduce pain and improve recovery for women having a minimally invasive hysterectomy. Researchers enrolled 72 women and compared those who used the app be…

This study tested two alternative pain management methods for patients recovering from liver surgery. Researchers compared continuous local anesthetic injection near the surgical site with continuous spinal pain relief to see which better reduces morphine use after surgery. The t…

This study looked back at 670 women who had hysterectomy surgery to compare two pain relief methods. Researchers wanted to see if giving morphine through a spinal injection works better and is safer than giving it through an IV drip during the first two days after surgery. The go…

This study tested whether a special nerve-block injection given at the end of gallbladder removal surgery helps reduce pain afterward. Sixty patients having the surgery were split into two groups: one received the injection, and the other did not. Researchers compared the patient…

This study tested whether specific non-opioid injections given around surgery time could effectively reduce pain after elective lower back (lumbar) surgery. It involved 75 patients who had surgery for a herniated disc, comparing pain levels to see if the approach could lessen the…

This study tested if the medication duloxetine could help reduce pain and the need for opioid painkillers after total knee replacement surgery. It involved 241 adults having knee replacement for arthritis, including some with a condition that makes them extra sensitive to pain. P…

This study tested different ways to manage pain after laparoscopic gallbladder removal surgery. Researchers compared a specific nerve-blocking technique (TAP block) against standard local numbing injections in 160 patients. They found the TAP block provided better pain relief for…

This study tested whether a targeted nerve block, given before surgery, could reduce pain and the need for strong opioid painkillers after breast cancer surgery. It involved 70 women having a specific type of breast cancer operation. Researchers compared the nerve block to standa…

This study compared two methods for managing pain after spinal fusion surgery. It tested whether a specific nerve block given before surgery or a large dose of local numbing medicine given at the end worked better than standard care alone. Researchers measured patients' pain leve…

This study compared two different nerve-block techniques to manage pain in children aged 1-7 after hip surgery. The goal was to find a safe and effective way to control pain while reducing the need for strong opioid painkillers, which can have serious side effects. Researchers te…

This study aims to understand why some people develop long-term pain after surgery while others recover without it. Researchers will follow 2,500 adults having major surgery, collecting information about their health, pain sensitivity, and daily experiences using smartphone surve…

This study aims to understand if specific brain wave patterns measured during surgery are linked to how much pain a patient feels after waking up. Researchers will record brain activity from 80 adults having planned abdominal surgery while they receive small, calibrated electrica…

This study looked at whether a person's body weight affects how much pain they feel after surgery for a slipped disc in the lower back. Researchers studied 75 adults who had this surgery and received a specific type of pain-blocking injection. The goal was to understand if higher…

This study aimed to create detailed maps showing which areas of skin go numb after different types of pain-blocking injections used during breast cancer surgery. Researchers worked with 36 patients to compare three common nerve block techniques and see how well they covered the s…

This study looked at whether the timing of a specific pain-blocking injection (Erector Spinae Plane block) affects heart electrical patterns in people having gallbladder removal surgery. Researchers compared giving the block before surgery, after surgery, or not at all. They meas…