New cocktail may ease C-Section pain and cut morphine use

NCT ID NCT05671172

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested whether adding hyaluronidase to the numbing drug bupivacaine improves pain relief after cesarean section. 114 women received a nerve block with either bupivacaine alone or bupivacaine plus one of two doses of hyaluronidase. The goal was to see if the combination extends pain relief and reduces the need for additional morphine.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
hyaluronidase added to bupivacaine
What this could lead to
If it works, this could lead to better pain control after C-section with less need for strong painkillers like morphine.
What could go wrong
This is a small, completed study with 114 participants. The results may not apply to all patients, and adding hyaluronidase could cause allergic reactions or other side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Samar Rafik Amin

    Banhā, Qalyubia Governorate, 13511, Egypt

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