CBD may offer safer pain relief after knee surgery
NCT ID NCT04749628
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a CBD oral solution (Epidiolex) can help manage pain and reduce the need for opioids in 37 adults undergoing double knee replacement. Participants received either a placebo or one of two CBD doses. The goal was to see if CBD could lower opioid use while still providing adequate pain control.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Locations
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Hospital for Special Surgery
New York, New York, 10021, United States