Pain relief showdown: ketamine vs lidocaine after surgery

NCT ID NCT07248384

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested two common painkillers, ketamine and lidocaine, to see which works better for pain after gallbladder removal. 76 adults were randomly assigned to receive one of the drugs right after surgery. Researchers measured their pain levels over the next 24 hours. The goal is to find a better way to manage post-surgery pain.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
ketamine and lidocaine (given as single IV injections after surgery)
What this could lead to
If one drug works better, it could offer a simple, low-cost way to ease pain after gallbladder surgery.
What could go wrong
This is a small, early-phase trial with only 76 people. Results may not apply to other surgeries or patients, and both drugs have side effects like dizziness or nausea.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

agnosia cholelithiasis Pain Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Liaquat National Hospital, Anesthesiology Department

    Karachi, Sindh, 74800, Pakistan

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