Which nerve block eases knee replacement pain better?
NCT ID NCT07231692
First seen Nov 17, 2025 · Last updated Jun 23, 2026 · Updated 29 times
Summary
This study looked at 60 adults who had knee replacement surgery to see which of two nerve block combinations worked better for pain. One group got a biceps femoris short head block plus an adductor canal block, and the other got an IPACK block plus an adductor canal block. Researchers measured how much opioid pain medicine patients used and their pain scores in the first 24 hours after surgery.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Karabuk Training and Research Hospital, Department of Anesthesiology and Reanimation
Karabük, Karabük Province, 78200, Turkey (Türkiye)
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
nerve block (biceps femoris short head block or IPACK block combined with adductor canal block)
What this could lead to
If one block combination works better, it could help reduce opioid use and improve recovery after knee replacement surgery.
What could go wrong
This is a small observational study (60 people) that only looks at existing practices, not a controlled experiment. Results may not apply to all patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.