New study tests better pain relief after liver surgery

NCT ID NCT03238430

Completed Symptom relief Sponsor: University Hospital, Lille Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at two methods to control pain after liver surgery: continuous wound infiltration with a local anesthetic (ropivacaine) and a single spinal injection of morphine. The goal was to see which approach reduces the need for additional morphine and lowers the chance of chronic pain at 3 and 6 months after surgery. A total of 186 patients took part, and the results could help improve recovery after liver operations.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Ropivacaine and intrathecal morphine
What this could lead to: If successful, this could show that one of these methods is better at controlling pain after liver surgery, reducing the need for morphine and lowering the risk of long-term pain.
What could go wrong: This is a completed Phase 2/3 trial with 186 participants, so results are available but may not apply to all patients. The study compares existing techniques, so no breakthrough is expected.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PAIN, POSTOPERATIVE

Contacts and locations

Locations

CHRU , Hôpital Claude Huriez

Lille, France

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