New eye drops could ease pain and swelling after cataract surgery

NCT ID NCT04130802

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This Phase 2 trial tested OCS-01 eye drops in 153 adults who had cataract surgery. The drops aim to reduce eye inflammation and pain. Participants received either a once-daily or twice-daily dose of OCS-01 or a placebo. The study measured how many people had no signs of inflammation or pain after treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

OCS-01 (dexamethasone cyclodextrin nanoparticle eye drops)

What this could lead to

If successful, this could provide a more effective and convenient eye drop option to manage pain and inflammation after cataract surgery.

What could go wrong

This is a Phase 2 trial with only 153 participants, so results may not hold up in larger studies. The treatment is compared to a placebo, not existing standard care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Inflammation keratitis Pain Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Medical cennre

    Petaluma, California, 94954, United States

  • Medical center

    Roseburg, Oregon, 97471, United States

  • Medical center

    Houston, Texas, 77008, United States

  • Medical center

    San Antonio, Texas, 78229, United States