New eye drops could ease pain and swelling after cataract surgery

NCT ID NCT04130802

Completed Symptom relief Sponsor: Oculis Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This Phase 2 trial tested OCS-01 eye drops in 153 adults who had cataract surgery. The drops aim to reduce eye inflammation and pain. Participants received either a once-daily or twice-daily dose of OCS-01 or a placebo. The study measured how many people had no signs of inflammation or pain after treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: OCS-01 (dexamethasone cyclodextrin nanoparticle eye drops)
What this could lead to: If successful, this could provide a more effective and convenient eye drop option to manage pain and inflammation after cataract surgery.
What could go wrong: This is a Phase 2 trial with only 153 participants, so results may not hold up in larger studies. The treatment is compared to a placebo, not existing standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Inflammation keratitis Pain Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INFLAMMATION CORNEAL PAIN, POSTOPERATIVE

Contacts and locations

Locations

Medical cennre

Petaluma, California, 94954, United States
Medical center

Roseburg, Oregon, 97471, United States
Medical center

Houston, Texas, 77008, United States
Medical center

San Antonio, Texas, 78229, United States

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