Sleep aid melatonin may cut painkiller needs after wisdom tooth removal

NCT ID NCT04791943

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether taking melatonin for three nights before wisdom tooth surgery could lower pain and the need for pain medication afterward. Sixty adults aged 18-35 took either melatonin or a placebo before their surgery. Researchers measured how many pain pills they used and checked inflammatory markers in their blood.

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Conditions

The condition(s) this trial relates to.

opiate dependence Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Montefiore Medical Center Department of Dentistry

    The Bronx, New York, 10467, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.