Sleep aid melatonin may cut painkiller need after wisdom tooth removal

NCT ID NCT04791943

First seen Feb 01, 2026 · Last updated Apr 29, 2026 · Updated 9 times

Summary

This study tested if taking melatonin for three nights before wisdom tooth surgery can lower pain and the amount of pain medication needed afterward. Sixty adults aged 18-35 took either melatonin or a placebo before their surgery. Researchers measured how many pain pills they used and checked inflammatory markers in their blood.

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Contacts and locations

Locations

  • Montefiore Medical Center Department of Dentistry

    The Bronx, New York, 10467, United States

Conditions

Explore the condition pages connected to this study.