Jaw surgery pain study: which numbing drug works best?

NCT ID NCT06450028

Completed Symptom relief Sponsor: Boston Children's Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Aug 05, 2026 · Updated 6 times

Summary

This study compared two common numbing drugs, lidocaine and bupivacaine, in 60 people aged 15–35 having jaw surgery. Researchers measured pain, numbness, and touch sensation after surgery. The goal is to find which drug gives patients a better recovery experience.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: lidocaine and bupivacaine (local anesthetics)
What this could lead to: If this study shows one drug works better, surgeons may use it to reduce pain and numbness after jaw surgery.
What could go wrong: This is a small, completed Phase 4 trial with only 60 participants. Results may not apply to everyone, and both drugs are already standard care, so no major breakthrough is expected.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Hypesthesia Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NUMBNESS PAIN, POSTOPERATIVE PERCEPTION OF TOUCH TEMPERATURE SENSATION

Contacts and locations

Locations

Boston Children's Hospital

Boston, Massachusetts, 02115, United States

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