PAIN, POSTOPERATIVE

This study tests three different medicines placed inside infected baby molars to see which works best. It involves 108 children aged 4-8 with dead or infected teeth. The goal is to reduce pain, swelling, and signs of infection on X-rays, while also checking how well the medicines…

This study tests whether watching immersive 360-degree videos through a VR headset can reduce pain, anxiety, and the need for strong painkillers during dressing changes after burn surgery. About 80 adults who had skin grafts will try the VR distraction tool. The goal is to find a…

This study compares a slow-release painkiller (Exparel) to the standard painkiller (bupivacaine) for pain after eye removal surgery. About 88 adults having their eye removed will be randomly assigned to receive one of the two medications during surgery. The goal is to see if the …

This study planned to see if adding ear acupuncture during surgery to repair a broken lower leg could lower the amount of opioid painkillers patients needed afterward. It was designed for adults aged 18 to 64 having ankle surgery. However, the study was withdrawn before any parti…

This study looks at whether giving magnesium through an IV during hip surgery can lower pain and the amount of pain medicine needed after the operation. About 50 adults having a specific type of hip surgery are taking part. The goal is to find a simple way to improve recovery and…

This study tests if a new 3-point stitch method for holding mesh in place during hernia repair leads to less pain and fewer problems than the usual method. About 64 adults having hernia surgery will take part. The goal is to see which approach helps patients heal better.

This study planned to test whether giving patients ear acupuncture during wrist fracture surgery would lower their need for opioid painkillers afterward. It was designed for adults aged 18-64 having a specific type of wrist repair. However, the study was withdrawn before any part…

This study tests whether listening to music before or during hernia repair surgery can lower pain and reduce the need for strong painkillers afterward. About 308 adults having hernia surgery at one center will take part. Researchers will compare pain scores and narcotic use betwe…

This study looks at whether adding a mild electrical stimulation device (like a TENS unit) to standard pain management can reduce pain and improve quality of life for 90 people recovering from lung cancer surgery. The treatment is non-invasive and aims to lower inflammation and r…

This study tests whether a non-invasive treatment called repetitive transcranial magnetic stimulation (rTMS) can reduce chronic neuropathic pain—pain from nerve damage that lasts over 6 months. About 32 adults with conditions like post-stroke pain, trigeminal neuralgia, or spinal…

This study tests whether a nerve block called erector spinae plane block (ESPB) can reduce the need for morphine after minimally invasive spinal fracture surgery. 86 adults will be randomly assigned to receive either the nerve block or a placebo. The main goal is to see if the bl…

This study looks at whether prescribing fewer opioid painkillers after laparoscopic hysterectomy still keeps patients comfortable. About 120 adults having this surgery for non-cancer reasons will be randomly assigned to get a standard or reduced opioid prescription. The goal is t…

This study aimed to see if injecting a numbing medicine (bupivacaine) near the chest muscles could lower pain and the need for strong painkillers after open-heart surgery. It planned to compare the numbing medicine against a saltwater placebo in about 100 adults. However, the stu…

This study aimed to see if a short course of steroids after knee replacement surgery could reduce pain, improve movement, and lower the need for painkillers. It was designed for adults having their first knee replacement. However, the study was withdrawn before any participants w…

This study tests a pain control method called intercostal nerve cryotherapy for people having minimally invasive lung surgery. The treatment freezes nerves between the ribs to block pain signals. Researchers will compare pain levels and morphine use between patients who receive c…

This study tests whether a nerve block given before heart surgery can reduce pain and the need for strong painkillers afterward. About 150 adults having certain heart surgeries will get either a long-lasting or standard numbing medicine. The goal is to see which works better for …

This pilot study is testing whether a daily 20-minute meditation program, done for 2-4 weeks before and 2 weeks after kidney stone surgery, can improve pain and anxiety in patients aged 12 and older. Half of the 50 participants will learn meditation, while the other half will rec…

This study tests a new pain medicine called NTM-001 for people with moderate-to-severe pain after bunion surgery. About 341 adults aged 18 to 65 will receive either NTM-001, a placebo (inactive treatment), or IV morphine to compare how well each controls pain over 24 hours. The g…

This study looks at three different ways to manage pain after surgery for pectus excavatum, a common chest wall deformity in teens. The goal is to find which method works best to reduce pain and the need for strong painkillers. About 158 patients aged 12 to 21 will be randomly as…

This study aimed to compare two different nerve block techniques used alongside a standard pain block to manage pain after hip surgery in teenagers and young adults. The goal was to see if one method provided better pain relief or reduced the need for opioid painkillers. The stud…

This study compares two types of nerve blocks (serratus plane block and rhomboid intercostal plane block) to see which provides better pain relief after breast reduction surgery. Ninety women undergoing the surgery will receive one of the two blocks before anesthesia. The main go…

This study tests a Pain and Coordination Plan (PAC-plan) to reduce opioid use and improve quality of life in adults after accidental injury. About 271 participants will either get the plan or usual care. The plan includes an opioid management schedule, a follow-up doctor visit wi…