Nanoparticles take on tooth infections in kids: a new hope?
NCT ID NCT06926322
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a new nano-based paste (chitosan-coated silver nanoparticles) works better than a standard antibiotic paste for treating infected baby molars in children aged 4-8. The goal is to reduce pain, swelling, and infection, and to see which paste kills bacteria best. The trial involves 108 children and compares three different pastes placed inside the tooth.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- chitosan-coated silver nanoparticles and double antibiotic paste (metronidazole and ciprofloxacin)
- What this could lead to
- If it works, this could offer a simpler, more effective treatment for infected baby teeth, reducing pain and the need for extractions.
- What could go wrong
- This is a small, early-stage trial (108 children) testing a new nano-formulation. The nanoparticles may not work better than the standard paste, and long-term safety in young children is unknown.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Faculty of dentistry Ain shams university
Cairo, Egypt
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