PAIN, POSTOPERATIVE

This study tests two methods of giving methadone to adults undergoing complex spine surgery. One group gets a standard dose based on body weight, while the other receives smaller, incremental doses until breathing slows. The goal is to see which approach reduces the need for addi…

This study looked at whether adding an iPACK nerve block to standard pain treatments (adductor canal block and local injections) helps people feel less pain and recover faster after total knee replacement. Only 10 people were enrolled before the study was stopped early. The goal …

This study tested a small device worn on the ear that uses mild electrical pulses to help control pain after a liver transplant. The goal was to see if it could reduce the need for strong painkillers like opioids. The study was stopped early and included 27 adults waiting for a l…

This study compared two nerve block methods for controlling pain after chest surgery in children and teens. The goal was to see if a newer block (erector spinae) was as good as the standard one (paravertebral) at reducing pain and the need for strong painkillers. The study was st…

This study tested two standard pain relief methods after below-knee amputation: a long-lasting numbing injection (liposomal bupivacaine) versus a continuous nerve catheter that delivers numbing medicine. The goal was to see which provides better pain control and reduces the need …

This study tested a medicated skin patch (dexmedetomidine) to see if it could reduce pain after tummy tuck surgery. It included 179 adults scheduled for abdominoplasty. The patch was compared to a placebo to measure pain intensity over time.

This study looked at whether a device called the Bridge system could help manage pain after hip replacement surgery. Only 5 people took part before the study was stopped early, so the results are not reliable. The goal was to see if the device could reduce the need for painkiller…

This study looked at how much of the pain medicine ropivacaine gets into the blood of infants and toddlers (0-4 years old) who received a nerve block for pain after chest surgery. The goal was to check if the levels were safe. The study was stopped early and included 26 children.