Tiny patients, big questions: how much painkiller reaches the blood?

NCT ID NCT02860091

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how much of the pain medicine ropivacaine gets into the blood of infants and toddlers (0-4 years old) who received a nerve block for pain after chest surgery. The goal was to check if the levels were safe. The study was stopped early and included 26 children.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ropivacaine (Naropin)

What this could lead to

If successful, this could help doctors understand safe dosing of ropivacaine for pain control in very young children after chest surgery.

What could go wrong

This was a small, early study that was terminated before completion, so results are limited. It only measured drug levels, not whether the pain relief was effective.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

esophageal atresia Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Boston Children"S Hospital

    Boston, Massachusetts, 02118, United States