Which painkiller-free method works best for teens after chest surgery?

NCT ID NCT04211935

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares three pain management techniques for teenagers undergoing minimally invasive repair of pectus excavatum (a sunken chest). The methods are: patient-controlled analgesia (PCA, where the patient pushes a button for pain medicine), erector spinae block (a nerve block with a continuous infusion pump), and intercostal nerve cryoablation (freezing nerves to reduce pain). The goal is to see which approach leads to the shortest hospital stay, least opioid use, and best pain control. About 158 participants aged 12–21 will be randomly assigned to one of the three groups.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
nerve freezing (cryoablation), nerve block (erector spinae block), and patient-controlled analgesia (PCA)
What this could lead to
If successful, this study could identify the most effective pain control method for teens recovering from pectus excavatum surgery, potentially reducing opioid use and hospital stays.
What could go wrong
This is a single-center trial with 158 participants, so results may not apply to all hospitals or patients. Each method has its own risks, such as infection or nerve damage, and the study is not designed to prove long-term benefits.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative pectus excavatum

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Children's Hospital Colorado

    Aurora, Colorado, 80045, United States

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