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Which nerve block keeps lungs stronger after chest surgery?

NCT ID NCT06584201

Symptom relief Sponsor: Başakşehir Çam & Sakura City Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 19, 2026 · Last updated Aug 27, 2026 · Updated 3 times

Summary

This trial compares two ultrasound-guided nerve blocks—erector spinae plane block and paravertebral block—for pain relief after minimally invasive chest surgery (VATS). The goal is to see which method better preserves lung function, as measured by breathing tests, and reduces the need for morphine. Adults aged 18-65 undergoing VATS will receive one of the two blocks before surgery, and their lung function and pain medication use will be tracked for 24 hours afterward.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Erector spinae plane block (ESPB) and paravertebral block (PVB), two ultrasound-guided nerve block procedures for postoperative pain relief.
What this could lead to
If one block proves better at preserving lung function and reducing opioid needs, it could become the preferred pain relief method for chest surgery, speeding recovery.
What could go wrong
This is a small, early-stage comparison, so results may not apply broadly. Nerve blocks carry risks like infection, bleeding, or incomplete pain relief.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

70 people

The number who actually took part.

Started

Nov 2024

Finished

Sep 2025

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Both genders * Being between the ages of 18 and 65 * ASA(American Society of Anesthesiologists) I-II-III * Body mass index between 19 and 30kg/m2 * Providing voluntary participation * Must be fully oriented and able to cooperate Exclusion Criteria: * ASA(American Society of Anesthesiologists) IV-V * Patients who refuse to participate in the study * Patients under 18 years of age * Patients over 65 years of age * Presence of active infection in the area to be treated * Chronic pain and constant analgesic use * Patients with coagulation disorders * Patients who cannot cooperate with postoperative pain follow-ups * Cases taken urgently * Patients with severe renal failure (creatinine\>2mg/dl) * Severe impairment of heart function (New York Heart Association Functional Classification III-IV) * Patients with known allergies to bupivacaine and other amide local anesthetic substances.

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Conditions

The condition(s) this trial relates to.

opioid abuse Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Opioid use Pain, postoperative Respiratory function loss

Contacts and locations

Locations

  • Basaksehir Çam Ve Sakura City Hospital

    Istanbul, Turkey (Türkiye)

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