Could a simple injection cut Post-Surgery painkiller use?
NCT ID NCT04260854
First seen Jul 01, 2026 · Last updated Jul 01, 2026
Summary
This study tests whether injecting bupivacaine, a common numbing medication, into the surgical site after skin surgery can improve pain control. About 100 adults having skin surgery will receive either bupivacaine or a saline placebo injection. Participants will track their pain medication use for three days after surgery to see if the bupivacaine group needs fewer painkillers.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
bupivacaine hydrochloride
What this could lead to
If it works, this could offer a simple way to better manage pain after skin surgery and reduce reliance on opioid painkillers.
What could go wrong
This is a small, early-phase pilot study, so results may not be conclusive. The benefit over standard care may be small or absent.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Northwestern University Department of Dermatology
Chicago, Illinois, 60611, United States