Could a simple nerve block cut opioid use after heart surgery?

NCT ID NCT06077422

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a nerve block given before heart surgery can reduce pain and the need for opioid painkillers afterward. About 150 adults having heart surgery will receive either a long-acting or standard form of the numbing drug bupivacaine via ultrasound-guided injection. Researchers will track how much opioid medication patients need in the first five days after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bupivacaine (as liposomal or standard injection)

What this could lead to

If it works, this could offer a better way to manage pain after heart surgery, reducing the need for strong opioids.

What could go wrong

This is a small pilot study, so results may not apply to all patients. The nerve block may not provide significant benefit over standard care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

heart disorder opioid abuse Pain Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Rutgers RWJMS

    New Brunswick, New Jersey, 08903, United States