ASTHMA

This early-stage study tests a new experimental drug, PF-08103402, for the first time in people. It includes healthy adults and adults with mild-to-moderate asthma to check safety, how the drug moves through the body, and whether food affects its absorption. Participants take the…

This study tests whether tezepelumab, an injectable drug, can reduce severe asthma attacks in children aged 5 to 11 with hard-to-control asthma. About 231 kids will receive either tezepelumab or a placebo, alongside their usual asthma medicines. The main goal is to see if the dru…

This study tests whether a new propellant (HFA-152a) in salbutamol inhalers works as well as the current one (HFA-134a) for people with mild asthma. 84 adults aged 18-65 will receive single doses of the inhaler or a placebo. The main goal is to measure how well the inhaler protec…

This study compares a new version of an asthma inhaler that uses a climate-friendly propellant to the current version. About 780 adults with mild to moderate asthma will try both inhalers to see if they work equally well. The goal is to ensure the greener option is just as effect…

This phase 3 trial tests a new inhaler that combines fluticasone (an anti-inflammatory) and albuterol (a fast-acting bronchodilator) for people 12 and older with asthma. Over 4 weeks, researchers will measure lung function and safety in 724 participants. The goal is to see if the…

This study tests whether depemokimab, an injected biologic drug, can reduce severe asthma attacks and help patients achieve remission when added to standard care. About 456 adults and adolescents with type 2 asthma at risk of flare-ups will receive either depemokimab or a placebo…

This study tests whether an inhaled drug called LQ036 can improve lung function and asthma control in people whose asthma is not well managed with current treatments. About 216 participants will inhale the drug or a placebo once daily for 24 weeks. The main goal is to see if LQ03…

This study tests whether the experimental drug brenipatide can reduce asthma attacks and improve breathing in adults whose moderate-to-severe asthma is not well controlled by current treatments. About 531 participants will receive either brenipatide or a placebo for 52 weeks. The…

This study tests whether weekly phone calls with education, relaxation techniques, and motivational interviewing can help adults with asthma who are anxious about using their inhalers. 216 participants will be split into two groups: one gets the extra phone support, the other get…

This Phase 3 trial tests an injectable drug called TQC2731 in 660 adults with severe asthma that is not well controlled by high-dose inhalers. Participants will receive either the drug or a placebo every 4 weeks for a year. The goal is to see if the drug reduces asthma attacks an…

This trial tests whether a 6-month personalized exercise program improves exercise capacity and asthma control in adults with severe asthma who are starting biologic therapy. Participants are randomly assigned to either the exercise program or standard advice to increase physical…

This study tests a new inhaler (PT027) against a standard one (PT007) in 440 teens aged 12 to 18 with asthma. The goal is to see if PT027 reduces the number of severe asthma attacks over a year. Participants must have had at least one severe attack in the past year and use daily …

This study tests a new once-daily inhaler called QMF149 (a combination of indacaterol and mometasone) against a standard asthma drug, budesonide, in 200 children aged 6 to 12 with asthma. The goal is to see if the new drug works better at improving lung function and controlling a…

This study looks at how well tezepelumab works for adults with chronic sinusitis and nasal polyps (with or without asthma). About 110 people will be followed for up to a year to see if their nasal polyps shrink and congestion improves. The goal is to understand real-world benefit…

This study tests whether benralizumab, an injected drug, can reduce asthma attacks in children aged 6 to 17 with severe eosinophilic asthma. About 200 participants will receive either benralizumab or a placebo, and researchers will track how long it takes for their first asthma f…

This study tests a new drug called tozorakimab in 540 adults with uncontrolled asthma despite using medium-to-high dose inhaled steroids. Participants will receive either the drug or a placebo as a shot under the skin. The main goal is to see if tozorakimab can reduce the number …

The ATHENA Project is testing a mobile health program designed to help African American young adults (ages 18-30) better control their asthma. Participants use a web-based app, have video chats with an asthma nurse, receive text messages, and track physical activity. The study ai…

This study tests whether screening for social needs like housing and food access, combined with referrals to community resources, can improve chronic disease outcomes for patients of color. Researchers will track blood pressure, cholesterol, blood sugar, depression, and asthma co…

This phase 3 study tests whether an inhaler combining budesonide (a steroid) and albuterol (a rescue drug) works better than albuterol alone for preventing severe asthma attacks. About 790 Chinese adults with asthma who have had at least one severe attack in the past year will us…

This study tests a program called TEACH-ER that provides asthma education in the emergency room and virtual follow-up visits at home. Researchers will enroll 430 children aged 3-12 with asthma to see if this approach reduces the need for future ER visits or hospital stays. The pr…

This study tests a new medicine called PF-07275315 for adults with moderate-to-severe asthma that is not well controlled. Participants will receive either the drug or a placebo as injections over 12 weeks. The goal is to see if the drug improves lung function and is safe. About 2…

This study tests whether a special education program called 'Asthma School' can help adults with asthma have fewer flare-ups and avoid emergency room visits or hospital stays. About 92 participants will be split into two groups: one that attends the school and one that gets usual…

This study tests a drug called depemokimab in 150 adults with severe asthma caused by a specific type of inflammation. The goal is to see if the drug can reduce mucus plugs and airway thickening in the lungs. Participants will receive the drug and have lung scans and breathing te…

This study tests whether adding an extra medication called glycopyrronium to standard asthma treatment can improve lung function in children aged 4 to 12. About 69 children with asthma will receive two different doses of glycopyrronium or a placebo, all on top of their usual inha…

This study tests whether giving adults with acute asthma a specific rescue inhaler (Airsupra) right in the emergency department can reduce the chance of another asthma attack within 3 months. About 1,860 participants will either receive Airsupra or continue usual care. The goal i…

This study aims to see which of two triple-combination inhalers works better for people with moderate to severe asthma that is not well controlled. About 20 adults will try both Trimbow and Trelegy Ellipta in a crossover design, and researchers will use special MRI scans to measu…

This study tracks 600 adults with asthma who are already prescribed Enerzair inhaler. Over 24 weeks, researchers will monitor side effects and how well the drug controls asthma in everyday life. No new treatment is given; it simply observes routine care.

This study tests an experimental drug called SIM0718 for people with asthma that is not well controlled by current inhalers. About 418 adults and teens aged 12 to 75 will receive either the drug or a placebo for one year. The main goal is to see if the drug reduces the number of …

This study tests whether a new digital spacer (Whizz) helps children aged 5-16 with asthma use their inhaler correctly and stick to their medication, compared to a standard spacer. Researchers will also look for biomarkers in blood and breath to improve diagnosis and understand h…

This study tests two doses of an inhaled drug called glycopyrronium in 42 children aged 6 to 12 with moderate to severe asthma. The goal is to see how well it opens airways and how safe it is compared to a placebo. Results will help decide the best dose for future combination tre…

This study follows 200 adults with uncontrolled asthma to see if the Trimbow inhaler (a triple-combination drug) improves symptom control over 6 months. Participants take the inhaler as part of their normal care, and researchers measure changes in asthma control scores and medica…

This study tests a nasal spray called RIG-101 in healthy people and those with asthma. First, it checks safety and tolerability. Then, asthma participants receive the spray daily and are exposed to a cold virus to see if it prevents asthma worsening. The trial is recruiting 82 ad…

This study tests if dupilumab, an injected drug, can help control asthma and severe wheezing in children aged 2 to 6. About 90 kids will receive either dupilumab or a placebo for a year, with an option to continue treatment. The goal is to see if it reduces serious asthma attacks…

This study tests whether a trained asthma navigator can help children aged 4-12 avoid repeat hospital visits after an asthma attack. Families in the Washington, DC area will be randomly assigned to receive either standard care or extra support from a navigator for 12 months. The …

This study is testing whether adults with sudden illnesses like infections, heart failure, or COPD can be safely treated at home instead of in a hospital. Researchers will compare costs, patient experience, and health outcomes for 3,000 participants who receive hospital-level car…

This study tests a short, scripted conversation between doctors and Black adults with uncontrolled asthma. The goal is to help patients and doctors make decisions together about asthma medicines. Researchers will enroll 400 adults at community health centers to see if this approa…

This phase 2 trial tests whether escitalopram, an FDA-approved antidepressant, can reduce severe asthma flare-ups in people with moderate to severe asthma who have had at least three attacks in the past year. About 105 participants will receive either escitalopram or a placebo pi…

This study tests whether using one inhaler (budesonide/formoterol) for both quick relief and daily control can reduce asthma attacks in children ages 6-18 in South Africa. About 1,038 kids with asthma will be split into two groups: one gets the single inhaler, the other gets sepa…

This study tests whether metformin, a common diabetes medication, can improve asthma control in overweight or obese adults whose asthma is not well-managed by their current inhalers. About 100 participants will take either metformin or a placebo for 24 weeks while tracking their …

This Phase 3 trial tests a new drug called 610 in 480 Chinese adults with severe eosinophilic asthma, a type of asthma linked to high levels of certain white blood cells. Participants receive either 610 or a placebo injection for 52 weeks. The main goal is to see if 610 reduces t…

This study is testing whether placing a temporary intragastric balloon (a soft balloon in the stomach) along with diet and exercise can improve asthma control in obese people whose asthma is not well managed by inhalers. About 84 participants will be randomly assigned to get the …

This study tests whether using a CPAP machine at night can help people with severe uncontrolled asthma who also have obstructive sleep apnea. Researchers will compare asthma control, lung function, and quality of life between those who receive CPAP plus lifestyle advice and those…

This study is testing whether the drug dupilumab can improve how well the lungs clear mucus in people with moderate-to-severe asthma. Thirty adults will receive either dupilumab or a placebo for 12 weeks. Researchers will measure mucus clearance using a special imaging technique,…

This study tests two ways to prevent asthma attacks: using inhaled steroids as a rescue inhaler (R-ICS) or taking azithromycin regularly. Researchers want to see which works better, alone or together, for people with poorly controlled asthma. About 3,200 people aged 13-75 with as…

This study tests whether a triple-combination inhaler (containing three drugs) works better than a standard dual-combination inhaler for teenagers aged 12-17 whose asthma is not well controlled. About 292 participants will use either the triple or dual inhaler daily for 24 weeks.…

This phase 3 trial tests a new drug called SHR-1905 for adults with severe asthma that is not well controlled by current treatments. The study will compare the drug to a placebo to see if it reduces asthma attacks and improves lung function. About 408 participants will take part …

This study is testing whether a smart inhaler cap and mobile app can help adults with poorly controlled asthma use their inhaler correctly and take their medication as prescribed. Sixty participants will use the smart system for one year while continuing their usual asthma treatm…

This study is testing a device called fenoTRACK that measures a gas in your breath linked to airway inflammation. It aims to see if the device can accurately track asthma control in both children and adults, whether used at home or in a clinic. The study includes people with unco…

This study is testing whether two simple breathing tests—oscillometry and FeNO—can help primary care doctors accurately diagnose asthma and COPD, compared to the usual specialist methods. Researchers will enroll 600 adults with suspected asthma or COPD across six countries. If th…

This study is enrolling 200 adults with asthma or COPD to see if combining chest CT scans with blood, sputum, and microbiome tests can more accurately tell the two diseases apart. Researchers will also look for clues that predict how well a patient will respond to treatment. No e…

This study is testing a device called Inflammacheck that measures chemicals in a person's breath to see if it can help tell the difference between lung cancer, other lung diseases, and healthy lungs. Researchers will collect breath samples from 140 adults and use AI to build a di…

This study is testing whether two simple, non-invasive tests—a breath test (FeNO) and a blood test (eosinophil count)—can accurately diagnose asthma in children aged 6 to 17. Currently, diagnosing asthma often requires complex hospital-based breathing tests. The researchers aim t…

This study evaluates the Breathing Pattern Assessment Tool (BPAT), a checklist used by physiotherapists to diagnose breathing pattern disorder—a condition where breathing is inefficient, causing breathlessness. Researchers will compare BPAT scores with patient questionnaires and …

This study is testing a special MRI scan that uses xenon gas to take detailed pictures of lung function. It includes 260 healthy volunteers and people with lung diseases like asthma, COPD, and cystic fibrosis. The goal is to see if this method can better detect and measure lung p…

This study looks at whether measuring inflammation in the breath and blood can help doctors prioritize who gets lung tests first when asthma is suspected. About 1,500 people aged 6 and older will take part. The goal is to see if this approach reduces delays for those most at risk…

This study tests a wearable device called the C-mo System that automatically detects and describes coughs. Researchers want to see if it can accurately count coughs, measure their intensity, and identify wheezing. 300 people aged 2 and older with cough-related conditions will wea…

This study tests a non-invasive imaging method called electrical impedance tomography (EIT) to monitor lung function in 400 adults with lung diseases like COPD, asthma, or pneumonia. Unlike standard spirometry, which requires active blowing, EIT works even in patients who cannot …

This study aims to find people who have asthma or COPD but don't know it yet. Participants will take an online questionnaire to see if they are at risk. Those at risk will be randomly assigned to receive early diagnosis and treatment from their doctor or usual care. The goal is t…

This study tests whether a smartphone app (AWARE) can accurately detect and monitor lung diseases like asthma, COPD, and cystic fibrosis by analyzing sound waves from the phone's speaker and microphone. Researchers will enroll 800 people aged 8-70, including healthy volunteers an…

This study tests a small wearable device called AeviceMD that listens to lung sounds and detects wheezing. Researchers want to see if the device is as accurate as a doctor using a stethoscope. About 160 children and adults with asthma will participate. If successful, the device c…

This study tests whether community health workers can help adults with chronic illnesses get up-to-date on COVID-19 and flu vaccines. Participants receive up to three counseling sessions in English or Spanish to address their vaccine concerns. The goal is to reduce health dispari…

This study is testing whether taking high-dose fish oil supplements during pregnancy can prevent asthma and persistent wheezing in early childhood. The trial will enroll 2000 pregnant Danish women with low blood levels of omega-3s. Participants take fish oil or placebo capsules d…

This study is testing whether taking a higher dose of vitamin D during pregnancy can prevent asthma and persistent wheezing in children up to age 3. Researchers will give 2000 pregnant women either vitamin D or a placebo daily from week 22-26 of pregnancy until one week after del…

This study tests an inhaled medication called ARO-RAGE in 36 adults with mild asthma that is triggered by allergens. The goal is to see if it improves small airway function after breathing in an allergen. Participants will receive either the drug or a placebo and be monitored for…

This study compares two types of aerobic exercise for children with asthma: virtual reality-based games and treadmill walking. Thirty children aged 10-17 will exercise twice a week for 8 weeks. Researchers will measure lung function, exercise capacity, and quality of life to see …

This study tests a new education program called WASP that teaches adults with asthma how to manage their condition day-to-day. The goal is to see if it helps control symptoms and improves quality of life. Forty adults will take part through their GP or primary care clinic.

This study tests two simple ways to reduce fear in children aged 3-6 who need breathing treatments (nebulization) for conditions like asthma. One group uses a toy-shaped nebulizer, another uses colorful distraction cards with games, and a third group gets standard care. Researche…

This study is testing a serious video game designed to improve emotional well-being in teenagers aged 12 to 16, both with and without chronic conditions like type 1 diabetes, asthma, and allergies. The game uses artificial intelligence to personalize activities that build coping …

This study tests an experimental oral drug called ENV-294 in 50 adults with moderate-to-severe asthma who already use standard inhalers. Participants take either the drug or a placebo once daily for 12 weeks. The goal is to see if the drug improves asthma control and lung functio…

This study looks at two types of exercise—energy conservation exercises and circuit training—to see which one better helps people with asthma manage shortness of breath, improve physical ability, and boost quality of life. About 32 adults with mild-to-moderate asthma will take pa…

This study tests a device called the Lung Master, which is meant to increase lung capacity by practicing slow, deep breaths. Twenty adults with or without breathing conditions will use the device daily at home for one month. Researchers will measure lung function before and after…

This study looks at whether adding regular walking to a low-calorie diet and metformin can improve lung function and weight in women who have both PCOS and asthma. Forty obese women will be split into two groups: one does exercise plus diet and metformin, the other only diet and …

This study tests a new way to help teenagers with asthma feel more in control of their condition. Teens aged 12-18 will either get a standard doctor visit or a visit where their confidence in managing asthma is assessed and addressed. After three months, researchers will compare …

This study tests whether giving intravenous magnesium (IVMg) early to children aged 2-17 with severe asthma in the emergency room can reduce their breathing distress more than a placebo. About 192 children who still have moderate-to-severe symptoms after initial treatment will re…

This study looks at whether adding specific breathing exercises (Buteyko or Pilates-style) to neck stretches can improve lung function and chest movement in adults with well-controlled asthma who also have forward head posture. Twenty-two participants will be assigned to one of t…

This study tests whether encouraging people with asthma to join an online support group can improve their symptoms and quality of life. 600 adults with poorly controlled asthma will be recruited. Their doctors will introduce them to a private online community where they can read …

This early-stage trial is testing a new drug, IBI3002, in adults with asthma that is not fully controlled by their current inhalers. About 12 to 27 participants will receive either the drug or a placebo by injection to see if it is safe and how the body processes it. The study is…

This study is testing a mobile app called ASTHMAXcel Voice to see if it helps adults with asthma better control their symptoms. The app sends reminders and educational content to users. Two hundred adults with persistent asthma will either use the app or receive usual care, and r…

This phase 3 trial tests whether a new drug called DW1807 works better than another drug (DW1807-R2) for people with year-round allergic rhinitis who also have asthma. About 274 adults will take one of the two drugs daily for 4 weeks. The main goal is to see if DW1807 improves na…

This study compares two techniques to help people with mild to moderate asthma breathe better: alternate nostril breathing (a type of yoga breathing) and using an incentive spirometer (a device that encourages deep breathing). Researchers will measure lung function and quality of…

This study looks at how your genes and your environment—like what you eat, breathe, and experience—work together to influence common diseases such as diabetes, heart disease, and asthma. Researchers are collecting health questionnaires, genetic data, and other information from 25…

This study follows 310 children aged 6 to 17, some with asthma and some without, for one year. Researchers want to learn how different types of asthma cause symptoms and sudden attacks. Participants keep track of cold symptoms and attend regular check-ups. The goal is to better u…

This study follows 400 adults aged 18–60 with moderate-to-severe asthma for up to 5 years. Researchers collect blood, urine, stool, dust, saliva, and lung samples at regular visits to see how bacteria and other environmental factors affect asthma symptoms and flare-ups. The goal …

This observational study is enrolling 355 adults with asthma in China to describe their clinical features, treatment patterns, and biological markers. Researchers will analyze lung function, imaging, and blood biomarkers to identify distinct asthma subtypes. The goal is to gather…

This study looks at how genes play a role in lung diseases like cystic fibrosis, asthma, and pulmonary fibrosis. Researchers will examine DNA from up to 3,500 people with and without lung disease to find genetic differences. The goal is to better understand what causes these cond…

This study looks at how the body's innate immune system responds to certain environmental exposures by measuring inflammation markers in blood. Researchers will collect blood samples from up to 725 healthy volunteers aged 18-45 to analyze how specific genes and proteins react. Th…

This study aims to better understand asthma and COPD by comparing immune markers in blood and airways of patients versus healthy volunteers. Researchers will analyze samples from 230 adults to identify distinct immune patterns linked to disease severity. The goal is to improve di…

This study looks at whether airway inflammation from asthma can cause brain inflammation and affect mood. Over six visits, 50 adults with mild asthma will complete questionnaires, computer tasks, allergy tests, breathing tests, blood draws, and brain scans. The goal is to underst…

This study looks at how asthma-related inflammation in the lungs might affect the brain and contribute to depression and anxiety. Researchers will compare brain scans, blood tests, and breathing tests between 100 adults with asthma and healthy volunteers. The goal is to understan…

This observational study will follow 500 adults in Taiwan who are receiving biologic treatments (such as omalizumab, mepolizumab, or dupilumab) for severe asthma. Researchers aim to see how well these drugs work in everyday practice, what factors predict better control, and how o…

This study uses advanced lung imaging to see how two asthma medications—albuterol alone and albuterol combined with budesonide—change airflow and blood flow in the lungs. About 40 adults with asthma will undergo scans before and after taking the medications. The goal is to better…

This study is observing 2,500 people with asthma to learn more about their symptoms, treatments, and quality of life in everyday settings. Participants will fill out surveys and may provide blood samples or lung function tests. The goal is to better understand how asthma affects …

This study aims to understand why people with asthma produce excess mucus. Researchers will collect airway cells from 24 volunteers (some with asthma, some healthy) using a thin tube passed into the lungs. By comparing the cells' genetic activity, they hope to pinpoint key molecu…

This study follows 6,000 children in Switzerland who have breathing issues like wheezing, coughing, or trouble breathing during exercise. Researchers collect information from doctor visits and surveys to better understand these problems and improve care. The goal is to learn more…

This study tracks 30 adults with asthma to see if changes in indoor and outdoor air pollution are linked to asthma attacks. Participants will have sensors placed in their homes to measure pollutants like fine particles and chemicals. The goal is to understand which pollutants are…

This study will check how many workers in an industrial zone in Thailand have asthma or COPD. About 310 adults will answer a questionnaire and take a breathing test. The goal is to find out how common these lung problems are in this group, not to test a treatment.

This study looks at whether a community program rooted in Native Hawaiian values can improve the well-being of young people aged 12-25 who have health issues like asthma, obesity, or mental health concerns. About 100 youth from the Wai'anae area will take part in cultural activit…

This observational study will track 289 adults with mild-to-moderate asthma in Thailand to see how many achieve remission and what factors are linked to it. Participants fill out a symptom questionnaire, take a breathing test, and give a blood sample once. The study does not test…

This study is a global registry that collects health information from 500 adults with severe asthma. The goal is to track how patients respond to treatments and understand the disease better. The data will help researchers develop improved care and therapies for severe asthma.

This pilot study is measuring prednisolone levels in 120 people with inflammatory diseases like thyroid eye disease, vasculitis, COPD, asthma, and others. Participants take high-dose prednisolone as part of their routine care, and researchers take timed blood samples to see how t…

This study tests a soft, wearable stethoscope that can continuously listen to a child's breathing and detect wheezing, a sign of an asthma attack. Researchers at Emory University will enroll 25 children hospitalized for asthma to wear the device for up to 8 hours. The goal is to …

This study looks back at how biologic drugs are being used to treat severe asthma in Hong Kong. Researchers will review the medical records of 360 adults to see which biologics are prescribed, how well they control asthma, and any side effects. The goal is to understand current p…

This study looks at how genes are linked to different types and severities of asthma in Chinese patients. Researchers will collect genetic data from 2,000 people with asthma to find common gene variants. The goal is to better understand asthma in this population, which has been u…

This study looks at how tiny organisms in the airways, like bacteria and viruses, relate to different types of asthma in adults. Researchers will collect samples from 140 adults with asthma to see if certain microbial patterns are linked to asthma severity and control. The goal i…

This study follows 500 adults in Hong Kong with severe asthma who are on high-dose treatments (step 4 or 5 of GINA guidelines). Researchers will track how well their asthma is controlled and how often they have flare-ups over two years. The goal is to gather local data to help do…

This study looks at whether salbutamol, a common asthma medication, can improve exercise performance in non-asthmatic endurance athletes. Researchers will test if a select group of athletes with breathing limitations might benefit from the drug. The study involves 64 healthy, hig…

This study looks at whether tongue images and pulse wave data can help doctors better understand and monitor asthma in children aged 5 to 18. Researchers will collect these non-invasive measurements during routine clinic visits and compare them with standard lung function tests. …

This study explores whether machine learning can analyze breathing test results to predict chronic respiratory diseases like asthma and COPD. Researchers will compare a newer technique called oscillometry with standard spirometry in 50 adults. The goal is to see if this approach …

This study is testing two new types of lung MRI that use special gases (xenon and perfluoropropane) to create detailed images of lung function. Researchers will compare these scans in 30 people with cystic fibrosis, asthma, and healthy volunteers to see if they can spot lung prob…

This study is gathering detailed information from 470 adults with chronic inflammatory lung diseases like asthma, COPD, and cystic fibrosis, as well as healthy volunteers. Researchers will analyze clinical, biological, and lifestyle factors to identify distinct disease subtypes. …

This study looks at the bacteria (microbiomes) in the airways of infants under 2 years old with severe asthma. Researchers will collect blood, nasal swabs, and sputum samples to understand how these microbiomes relate to the disease. The goal is to find new ways to improve care a…

This study explores whether people who seek help for both their allergies and their mental health (like anxiety or depression) have better control over their symptoms. Researchers will look at health records from 200,000 adults over several years. The goal is to understand if com…

This study aims to understand how the throat and esophagus normally prevent stomach contents from reaching the throat in people with GERD. Researchers will use a thin tube with sensors placed through the nose to measure pressure, acid, and liquid movement, along with a tiny camer…

This long-term study follows 1,000 people with eczema and related allergies, plus healthy volunteers, to see what factors help the disease go into remission. Researchers will collect medical and lifestyle data to find patterns and possible biomarkers. The goal is to better unders…

This study looks at how the diaphragm, the main muscle used for breathing, works in people with lung diseases like asthma, COPD, fibrosis, and pulmonary hypertension. Researchers want to see if diaphragm problems are linked to shortness of breath. About 800 adults will take breat…

This study looks at blood and urine samples from 100 children aged 12-17 with asthma to find chemical markers that signal an asthma attack. Participants continue their usual asthma medications. The goal is to better understand how asthma changes in the body, which could lead to e…

This study tests whether computer-based decision support tools can help doctors reduce unnecessary antibiotic use in children with lower respiratory tract infections like pneumonia, bronchiolitis, and asthma flare-ups. Most of these infections are caused by viruses, not bacteria,…

This study will enroll 900 children aged 5-17 with asthma to see if remote monitoring—using routine health data and a smartphone app—can predict asthma attacks. Researchers will track whether this system reduces the number of attacks compared to past averages. A subset of high-ri…

This study looks at two proteins, ezrin and Pip5k1α, in the airway muscles of people with and without asthma. Researchers will analyze lung tissue samples from 120 adults to see if these proteins are different in asthma patients. The goal is to better understand asthma and find n…

This study aims to develop a simple, non-invasive way to detect lung diseases like cancer, asthma, and COPD by analyzing DNA and proteins from cough samples. Researchers will collect cough specimens from 2000 adults, including smokers and non-smokers, and compare them to samples …

This observational study will use CT scans to measure mucus plugging in the airways of people with asthma, COPD, or chronic cough, and compare them to healthy volunteers. Researchers hope to understand how mucus changes over time and find biomarkers that could guide treatment. Th…

This study looks at how fungi in the environment (like mold in homes) affect people with asthma, allergic bronchopulmonary aspergillosis (ABPA), and bronchiectasis. Researchers will collect dust and sputum samples from 125 adults aged 18–80 and follow them for 6 months. The goal …

This study looks at 60 adults aged 35-75 with allergic or eosinophilic asthma to see if their symptoms, breathing problems, and frailty levels differ. Researchers will measure lung function, breathlessness, fatigue, and quality of life. The goal is to help health professionals de…

This study looks at how the lungs of people with asthma react when exposed to common allergens like cat hair or dust mites. Researchers will use a bronchoscope to deliver tiny amounts of allergen into the lung and then collect fluid to study which immune cells show up. The goal i…

This study follows 1,000 adults who took part in earlier EGEA surveys, comparing those with and without asthma. Researchers will measure heart disease risk markers like the Framingham score and blood biomarkers. The goal is to understand if asthma itself increases cardiovascular …

This study tests a new care pathway for children having mild-to-moderate asthma attacks. The goal is to make sure every child gets the same high-quality treatment, like using a spacer with their inhaler. Researchers will track how well doctors follow the new plan and look for way…

This study tests two strategies to help doctors prescribe SMART therapy—a single inhaler for daily control and quick relief—for children with moderate to severe asthma. Researchers will use electronic reminders and education, plus a community health worker and nurse care manager,…

This study tests whether giving doctors extra training and electronic reminders helps them prescribe a modern asthma treatment called SMART for children with moderate to severe asthma. The study involves 18 children ages 5 to 18 at primary care clinics. Researchers will compare h…

This study looks at whether a breathing test called impulse oscillometry (IOS) can help doctors monitor asthma better than standard tests. Fifty adults with asthma will take IOS and other lung function tests, plus fill out questionnaires, at the start and again 3-6 months after a…

This study is for adults with asthma whose symptoms don't improve with standard inhalers. Researchers will use advanced MRI and CT scans to see if structural problems in the airways—like narrowing or mucus plugs—prevent inhaled medications from reaching the lungs. Participants wi…

This study surveys 384 adults in Türkiye who have completed a pulmonary rehabilitation program for lung conditions like COPD or asthma. Researchers want to learn how satisfied patients are and how the rehab team's structure affects their experience. No new treatment is being test…