Breathing new life into asthma imaging: can noble gas MRI reveal hidden lung damage?

NCT ID NCT02351141

First seen Jul 31, 2026 ยท Last updated Jul 31, 2026

Summary

This study is testing whether a special type of MRI, using inhaled noble gases like helium or xenon, can provide detailed images of lung structure and function in people with asthma. Researchers will scan 200 adults with asthma to measure how well air moves through the airways and into air sacs. The goal is to see if this imaging technique can offer a more complete picture of asthma's effects on the lungs than standard tests.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Hyperpolarized noble gas MRI (Helium-3 and/or Xenon-129)
What this could lead to
If successful, this imaging method could offer a new way to see how asthma affects the lungs, potentially improving diagnosis and treatment monitoring.
What could go wrong
This is an observational imaging study, not a treatment trial, so it won't directly change patient care. The technique may not prove superior to existing methods like CT.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Robarts Research Institute; The University of Western Ontario; London Health Sciences Centre

    RECRUITING

    London, Ontario, N6A 5B7, Canada

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