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Fish oil in pregnancy may cut childhood asthma risk, major trial launches

NCT ID NCT06560255

Recruiting now Prevention Sponsor: Professor Klaus Bønnelykke Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether taking high-dose fish oil supplements during pregnancy can prevent asthma and persistent wheezing in early childhood. The trial will enroll 2000 pregnant Danish women with low blood levels of omega-3s. Participants take fish oil or placebo capsules daily from week 22-26 of pregnancy until one week after delivery. The main goal is to see if this reduces the number of children diagnosed with asthma or wheezing by age 3.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
n-3 fatty acid (fish oil)
What this could lead to
If it works, this could offer a simple, personalized way to reduce the risk of asthma and wheezing in early childhood.
What could go wrong
This is a large phase 3 trial, but previous studies on fish oil in pregnancy have had mixed results. The benefit may be small or not apply to all children.

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Conditions

The condition(s) this trial relates to.

allergic disease asthma atopic eczema bone fracture croup developmental disability digestive system infectious disorder Eczema Infections psychiatric disorder Respiratory Sounds respiratory tract infectious disorder childhood onset asthma prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALLERGY ASTHMA COGNITION DISORDERS IN CHILDREN CROUP DEVELOPMENT, CHILD ECZEMA FRACTURES, BONE GASTROINTESTINAL INFECTION PSYCHIATRIC DIAGNOSIS RESPIRATORY TRACT INFECTIONS WHEEZING

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Copenhagen University Hospital of Copenhagen

    RECRUITING

    Gentofte Municipality, DK-2820, Denmark

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