Prenatal vitamin d: a simple step to stop childhood asthma?

NCT ID NCT06570889

Recruiting now Prevention Sponsor: Professor Klaus Bønnelykke Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether taking a higher dose of vitamin D during pregnancy can prevent asthma and persistent wheezing in children up to age 3. Researchers will give 2000 pregnant women either vitamin D or a placebo daily from week 22-26 of pregnancy until one week after delivery. The goal is to see if this simple supplement can reduce the risk of early childhood asthma.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Vitamin D3 (cholecalciferol)
What this could lead to: If it works, this could lead to a simple, safe way to reduce the risk of asthma in young children by giving higher doses of vitamin D during pregnancy.
What could go wrong: This is a large phase 3 trial, but previous studies on vitamin D for asthma prevention have had mixed results. The effect may be small or limited to certain groups.

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Conditions

The condition(s) this trial relates to.

allergic disease atopic eczema bone fracture croup developmental disability digestive system infectious disorder Eczema Infections psychiatric disorder Respiratory Sounds respiratory tract infectious disorder asthma prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALLERGY ASTHMA COGNITION DISORDERS IN CHILDREN CROUP DEVELOPMENT, CHILD ECZEMA FRACTURES, BONE GASTROINTESTINAL INFECTION PSYCHIATRIC DIAGNOSIS RESPIRATORY TRACT INFECTIONS WHEEZING

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Copenhagen University Hospital of Copenhagen
RECRUITING

Gentofte Municipality, DK-2820, Denmark

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