New triple inhaler could help teens with Hard-to-Control asthma
NCT ID NCT05757102
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a triple-combination inhaler (containing three drugs) works better than a standard dual-combination inhaler for teenagers aged 12-17 whose asthma is not well controlled. About 292 participants will use either the triple or dual inhaler daily for 24 weeks. The main goal is to see if the triple inhaler improves lung function more than the dual one.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Fluticasone furoate, umeclidinium, and vilanterol (a triple-combination inhaler)
What this could lead to
If it works, this could offer a more effective daily inhaler option for teenagers whose asthma is not well controlled with current two-drug inhalers.
What could go wrong
This is a relatively small, short-term study (24 weeks) in a specific age group. The triple inhaler may not prove significantly better than the standard dual inhaler, and long-term safety in teens is not yet established.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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GSK Investigational Site
RECRUITINGBirmingham, Alabama, 35209, United States
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GSK Investigational Site
RECRUITINGMobile, Alabama, 36608, United States
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GSK Investigational Site
RECRUITINGParadise Valley, Arizona, 85253, United States
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GSK Investigational Site
RECRUITINGBakersfield, California, 93301, United States
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GSK Investigational Site
WITHDRAWNHuntington Beach, California, 92647, United States
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GSK Investigational Site
RECRUITINGMission Viejo, California, 92691, United States
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GSK Investigational Site
COMPLETEDRolling Hills Estates, California, 90274, United States
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GSK Investigational Site
WITHDRAWNWalnut Creek, California, 94598, United States
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GSK Investigational Site
RECRUITINGColorado Springs, Colorado, 80909, United States
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GSK Investigational Site
COMPLETEDAventura, Florida, 33180, United States
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GSK Investigational Site
RECRUITINGMiami, Florida, 33165, United States
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GSK Investigational Site
COMPLETEDMiami, Florida, 33173, United States
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RECRUITINGMiami, Florida, 33174, United States
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GSK Investigational Site
COMPLETEDSavannah, Georgia, 31406, United States
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GSK Investigational Site
RECRUITINGNormal, Illinois, 61761, United States
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GSK Investigational Site
RECRUITINGOwensboro, Kentucky, 42301, United States
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GSK Investigational Site
COMPLETEDColumbia, Missouri, 65203, United States
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GSK Investigational Site
RECRUITINGMissoula, Montana, 59808, United States
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GSK Investigational Site
RECRUITINGThe Bronx, New York, 10461, United States
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GSK Investigational Site
RECRUITINGCincinnati, Ohio, 45229, United States
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GSK Investigational Site
RECRUITINGCleveland, Ohio, 44106, United States
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GSK Investigational Site
COMPLETEDDayton, Ohio, 45404, United States
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GSK Investigational Site
RECRUITINGOklahoma City, Oklahoma, 73120, United States
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GSK Investigational Site
RECRUITINGCharleston, South Carolina, 29420, United States
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GSK Investigational Site
RECRUITINGDallas, Texas, 75225-6301, United States
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GSK Investigational Site
RECRUITINGKerrville, Texas, 78028, United States
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GSK Investigational Site
COMPLETEDPlano, Texas, 75034, United States
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GSK Investigational Site
COMPLETEDWaco, Texas, 76712, United States
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GSK Investigational Site
RECRUITINGBuenos Aires, C1023AAB, Argentina
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GSK Investigational Site
RECRUITINGBuenos Aires, C1425BEN, Argentina
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GSK Investigational Site
RECRUITINGRosario, 2000, Argentina
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GSK Investigational Site
RECRUITINGSan Miguel de Tucumán, T4000IHE, Argentina
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RECRUITINGSouth Brisbane, Queensland, 4101, Australia
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RECRUITINGJoondalup WA, Western Australia, 6027, Australia
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GSK Investigational Site
RECRUITINGSantiago, 8320000, Chile
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GSK Investigational Site
RECRUITINGEbdentown, 5018, New Zealand
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GSK Investigational Site
RECRUITINGCheongju Chungcheongbuk-do, 28644, South Korea
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GSK Investigational Site
WITHDRAWNGwangju, 501-757, South Korea
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GSK Investigational Site
COMPLETEDSeoul, 03722, South Korea
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GSK Investigational Site
RECRUITINGSeoul, 05505, South Korea
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GSK Investigational Site
WITHDRAWNSeoul, 1757, South Korea
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GSK Investigational Site
RECRUITINGSeoul, 2447, South Korea
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