New nasal spray aims to stop asthma Flare-Ups triggered by common cold

NCT ID NCT07488897

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a nasal spray called RIG-101 in healthy people and those with asthma. First, it checks safety and tolerability. Then, asthma participants receive the spray daily and are exposed to a cold virus to see if it prevents asthma worsening. The trial is recruiting 82 adults aged 18-65.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

RIG-101 (nasal spray)

What this could lead to

If successful, this could point toward a new treatment to prevent asthma flare-ups triggered by common cold viruses.

What could go wrong

This is an early combined Phase 1-2 trial with only 82 participants, so safety and efficacy are not yet proven. The viral challenge part is artificial and may not reflect real-world conditions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

asthma status asthmaticus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Medicines Evaluation Unit

    RECRUITING

    Manchester, M23 9QZ, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Virtus Respiratory Research Ltd

    NOT_YET_RECRUITING

    London, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••