ASTHMA

This study tested an oral drug called dexpramipexole in 654 people with severe eosinophilic asthma, a type of asthma linked to high levels of certain white blood cells. The goal was to see if the drug could reduce asthma attacks and improve lung function over 52 weeks. However, t…

This study tested a daily pill called dexpramipexole for people with severe eosinophilic asthma that was not well controlled by standard inhalers. The goal was to see if the drug could reduce serious asthma attacks over one year. The trial was stopped early, so results are limite…

This study tested an inhaled drug called ARO-MUC5AC in healthy people and those with moderate-to-severe asthma or COPD. The goal was to see if it is safe and how the body processes it. The study was stopped early, so results are limited. About 78 people were planned to take part.

This study tested an experimental drug called RPT193 in 38 adults with moderate-to-severe asthma that was not fully controlled by their usual inhalers. The goal was to see if the drug could prevent asthma attacks and improve lung function. The study was stopped early, so results …

This study looked at how a new chewable asthma tablet called fevipiprant works in children aged 6 to 12. The goal was to find the right dose and check for side effects. Only 11 children took part, and the study was stopped early, so results are limited.

This study looked at whether a 20% N-acetylcysteine (NAC) solution could improve lung function and reduce mucus in people with moderate-to-severe asthma. Only 4 participants were enrolled before the study was terminated. Each person received both NAC and a placebo in two-week per…

This study looked at what causes sudden, severe asthma attacks in adults aged 18 to 75. Researchers measured mucus thickness in patients having an asthma attack to better understand the disease and how inhaled steroids help. The goal was to find new ways to treat asthma, but the …

This study tested whether advanced CT scans can detect changes in bone density and marrow fat in people with asthma who take oral steroids. Researchers planned to compare steroid users to a control group. Only 2 people enrolled before the study was stopped, so results are very li…

This study looked at whether a specific gene (PDE4) affects how well children with asthma respond to the rescue inhaler salbutamol. Researchers planned to compare lung function changes in 99 children aged 6-18 based on their gene type. The study was terminated early, so results a…

This study followed 152 preschool children (ages 3-5) to see how being born early (before 37 weeks) affects lung function. Researchers measured breathing using special tests and checked for allergies. The goal was to learn more about asthma and allergic rhinitis risks in preterm …