New asthma pill shows promise in early trial

NCT ID NCT05935332

Terminated Disease control Sponsor: RAPT Therapeutics, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 study tested an experimental oral drug called RPT193 in 38 adults with moderate-to-severe asthma that was not fully controlled by standard inhalers. The goal was to see if RPT193 could reduce asthma attacks and improve lung function. The trial was terminated early, so final results are not available, but the data may still inform future research.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: RPT193
What this could lead to: If successful, RPT193 could offer a new oral option to help control moderate-to-severe asthma and reduce flare-ups.
What could go wrong: This was a small, early-phase trial that was terminated, so results are limited. It is unclear if RPT193 will prove effective or safe in larger studies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

asthma T2-high asthma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASTHMA

Contacts and locations

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Locations

Allergy and Asthma Associates of Santa Clara Valley Research Center

San Jose, California, 95117, United States
Allergy, Asthma & Sinus Ceneter SC

Greenfield, Wisconsin, 53228, United States
Allianz Research Institute

Westminster, California, 92683, United States
Allianz Research Institute CO

Aurora, Colorado, 80014, United States
Bensch Clinical Research LLC

Stockton, California, 95207, United States
Centrum Diagnostyczno Terapeutyczne MEDICUS Sp. z o.o. - Szpital

Lubin, 59-300, Poland
Centrum Medycyny Oddechowej Mróz Spółka Jawna

Bialystok, 15-044, Poland
Clinical Research Trials of Florida

Tampa, Florida, 33607, United States
Coral Research Clinical Corp

Miami, Florida, 33186, United States
Diagnostic-Consultative Center Convex Ltd.

Sofia, 1680, Bulgaria
IP Clinic Sp. z.o.o

Lodz, 90-752, Poland
Lekarze Specjaliści - J. Małolepszy i Partnerzy

Wroclaw, 54-239, Poland
MediTrial s.r.o

Jindřichův Hradec, 377 01, Czechia
Medical Center "ResearchExpert" Ltd

Varna, 9000, Bulgaria
Medical Center "Zadrave-1"

Kozloduy, 3320, Bulgaria
Medical Center Excelsior

Sofia, 1407, Bulgaria
Metroplex Pulmonary & Sleep Center

McKinney, Texas, 95069, United States
Michal Bogacki - Dobrostan

Wroclaw, 53-301, Poland
NZOZ Poradnie Specjalistyczne Atopia

Krakow, 31-159, Poland
OK Clinical Research LLC

Edmond, Oklahoma, 73034, United States
San Marcos Research Clinic

Miami Lakes, Florida, 33014, United States
Sonce Medical Research

Miami, Florida, 33133, United States
Specialized Hospital for Active Treatment of Pneumo-Phthisiatric Diseases - Vratsa

Vratsa, 3000, Bulgaria
Specjalistyczna Przychodnia Lekarska Alergo-Med sp. z o.o

Poznan, 61-578, Poland
Trialmed CRS (Piotrków Trybunalski)

Piotrkow Trybunalski, 97-300, Poland
Trialmed Sp z. o.o.o CRS Warszawa

Warsaw, Solipska, 02-482, Poland
University Multiprofile Hospital for Active Treatment

Stara Zagora, 6003, Bulgaria
Velocity Clinical Research Grants Pass

Grants Pass, Oregon, 97527, United States
Western Sky Medical Research

El Paso, Texas, 79903, United States

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