ASTHMA

This study aims to see which of two different asthma inhaler strategies works better for improving lung function in the small airways. It will involve about 130 adults whose asthma is not well controlled on their current medium-dose inhaler. Researchers will compare a higher-dose…

This study is testing if a new drug called QL2302 works as well and is as safe as an existing drug, Tezspire, for adults with severe asthma that isn't well-controlled by standard inhalers. About 636 participants will receive a monthly injection of one of the two drugs for a year,…

This study aims to compare two different triple-combination inhalers for adults with moderate-to-severe asthma that isn't fully controlled. Twenty participants will try each inhaler for 8 weeks, with tests to see how well each one opens airways and improves asthma symptoms. The g…

This study is testing whether an investigational drug called AK139 can help control moderate to severe asthma. It will involve about 160 adults whose asthma is not fully controlled. Researchers will measure if the drug improves lung function and reduces airway inflammation, while…

This study is testing whether following a vegan diet for 12 weeks can reduce body inflammation and help control asthma symptoms. It will compare adults with mild to moderate asthma and healthy adults, with half following a vegan diet and half following a regular diet. The goal is…

This study is testing if seeing a lung doctor and an ear/nose/throat doctor together in one visit is better than seeing them separately for adults who have both asthma and chronic sinus problems with nasal polyps. The main goal is to see if this combined approach helps patients u…

This study aims to see if giving a specific inhaler called Airsupra to adults when they leave the emergency room (ER) for an asthma attack helps prevent them from having another attack and needing urgent care within the next 3 months. It will compare this approach to the usual ca…

This study tests if a single steroid shot given in the emergency room works as well as a 5-day course of steroid pills to prevent adults with asthma attacks from needing to return. Researchers want to see if the one-time shot helps control asthma better and improves quality of li…

This study is testing if scheduling a telehealth appointment with an asthma specialist right from the emergency room (ER) helps adults get better follow-up care after an asthma attack. Researchers will compare this approach to the usual method of just giving a referral. They want…

This study aims to find out if installing a system to reduce radon gas in the home can help control asthma symptoms in children. It will involve 180 children with asthma who live in homes with radon. Researchers will compare a real radon reduction system to a fake one over 48 wee…

This study provides continued access to the medication benralizumab (Fasenra) for people with asthma, EGPA, or HES who completed a previous clinical trial and are still benefiting from the treatment. It aims to monitor the long-term safety of the drug while allowing participants …

This study is testing a new inhaled medicine called ARO-RAGE to see if it can help control asthma symptoms triggered by allergies. It will involve 36 adults with mild, stable asthma who are allergic to common substances. Researchers will measure how well participants' small airwa…

This study is testing if adding a traditional Chinese herbal formula called Liqin Zhike to standard asthma inhalers works better for a type of asthma that mainly causes a long-lasting cough. Researchers will compare two groups of 118 adults each over 14 months to see which treatm…

This large study aims to find the best way to manage moderate-to-severe asthma and prevent dangerous flare-ups. It will directly compare two established medication strategies—MART and PARTICS—in 4,100 adults who are at risk for asthma attacks. Researchers will track which approac…

This study aims to see if a new once-daily inhaler containing three medicines (QVM149) works better and is as safe as a common twice-daily inhaler for controlling asthma in teenagers. It will involve about 304 participants aged 12 to 18 whose asthma is not fully controlled on the…

This study is testing whether a slow-release version of the hormone supplement DHEA can help adults with asthma who already use steroid inhalers. Researchers want to see if adding DHEA improves asthma control and is safe, since standard asthma steroids can lower the body's natura…

This study is testing whether a new injection called depemokimab can help people with severe type 2 asthma have fewer serious asthma attacks. Researchers will give the injection or a placebo to about 456 teens and adults who have had recent asthma attacks despite using standard i…

This early-stage study is testing the safety and initial effectiveness of a new inhaled treatment for adults who have both moderate-to-severe allergic rhinitis (hay fever) and asthma. The treatment is a mist containing tiny particles (vesicles) derived from umbilical cord stem ce…

This study is testing whether a program called Body Awareness Therapy can help adults with asthma feel better. The therapy involves guided exercises focusing on breathing, posture, and gentle movement, led by a physical therapist. Researchers will compare this group to people rec…

This study is testing a special video game designed to help teenagers build emotional skills and improve their quality of life. It will involve 600 teens, including some with chronic conditions like type 1 diabetes and asthma. The game uses artificial intelligence to personalize …

This study is testing a new program called CALM, designed to help Black adults with asthma cope with stress. Researchers want to see if the program is practical and acceptable to participants, and if it might help people stick to their asthma medication and better control their s…

This study is testing whether Osteopathic Manipulative Treatment (OMT), a hands-on technique, can help adults with asthma breathe easier. Researchers will measure if OMT reduces lung inflammation and improves lung function in about 100 participants. The study focuses on people wh…

This study aims to understand how well asthma is controlled in children across China and to learn about the different types of inflammation in their airways. Researchers will observe 42,000 children with asthma, collecting information on their symptoms and treatments. The goal is…

This study aims to understand how climate change and air pollution affect allergies and asthma across Europe. Researchers will use artificial intelligence (AI) to analyze health and environmental data from nearly 2,000 people with allergic rhinitis in nine countries. The goal is …

This research study aims to understand how the body's immune cells behave differently in people with various lung diseases like asthma, COPD, and pneumonia. Researchers will analyze a single blood sample from 100 participants to look for patterns in how certain white blood cells …

This study aims to understand how common asthma medications affect air and blood flow in the lungs. Researchers will use special imaging scans on 40 adults with asthma before and after they take their regular inhaler medication. The goal is to gather detailed information about ho…

This study aims to find out how many adults with mild-to-moderate asthma in Thailand achieve remission, meaning they have no symptoms and need no medication. Researchers will survey 289 participants about their symptoms and perform breathing and blood tests. The goal is to unders…

This study aims to see if watching an episode of a popular medical TV drama can improve people's knowledge about asthma. Researchers will recruit 48 young adults online who have no medical background and do not have asthma themselves. Half will watch the show, and half will not, …