Asthma showdown: which inhaler strategy wins?

NCT ID NCT06596512

Not yet recruiting Disease control Sponsor: Brigham and Women's Hospital Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests two ways to use asthma inhalers to prevent serious attacks. One strategy (MART) uses a combination inhaler for daily control and quick relief. The other (PARTICS) adds a separate steroid inhaler whenever a rescue inhaler is used. About 4,100 adults with moderate-to-severe asthma will be followed for 16 months to see which approach reduces flare-ups better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Inhaled corticosteroids (ICS) and ICS/long-acting beta-agonist (LABA) combination inhalers
What this could lead to: If successful, this trial could show that the simpler PARTICS strategy is as good as or better than MART, giving patients more options to prevent asthma attacks.
What could go wrong: This is a large trial but compares two already-known treatments, so no breakthrough is expected. Results may not apply to all asthma patients, and individual responses can vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

asthma chronic asthma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASTHMA ASTHMA CHRONIC ASTHMA MODERATE PERSISTENT WITH EXACERBATION ASTHMA SEVERE PERSISTENT WITH EXACERBATION

Contacts and locations

Locations

Brigham and Womens Hospital

Boston, Massachusetts, 02115, United States
Duke University

Durham, North Carolina, 27705, United States
University of Pennsylvania

Philadelphia, Pennsylvania, 19122, United States
University of Wisconsin Madison

Madison, Wisconsin, 53792, United States
Washington University

St Louis, Missouri, 63110, United States
Yale University

New Haven, Connecticut, 06510, United States

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