Asthma gene clue: why some kids respond better to inhalers
NCT ID NCT03592212
First seen May 13, 2026 · Last updated Jun 23, 2026 · Updated 7 times
Summary
This study looked at whether a variation in the PDE4 gene influences how well children with persistent asthma respond to the common inhaler drug salbutamol. Researchers measured lung function before and after giving salbutamol to 99 children aged 6 to 18. The goal was to see if the gene variant could explain differences in drug response, which might one day help personalize asthma treatment.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Hôpital Necker -Enfants Malades
Paris, 75015, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Salbutamol
What this could lead to
If successful, this could help doctors predict which children with asthma will respond best to salbutamol, leading to more personalized treatment.
What could go wrong
This was a small, terminated study (99 participants) that only looked at a genetic link, not a treatment. The results may not apply to all children or change current care.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.