New asthma shot could help those failed by inhalers

NCT ID NCT06829784

Recruiting now Disease control Sponsor: Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 3 trial tests an injectable drug called TQC2731 in 660 adults with severe asthma that is not well controlled by high-dose inhalers. Participants will receive either the drug or a placebo every 4 weeks for a year. The goal is to see if the drug reduces asthma attacks and improves lung function and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: TQC2731 injection (a biologic that blocks TSLP protein to reduce airway inflammation)
What this could lead to: If successful, this could provide a new treatment option for people with severe asthma that is not well controlled by current inhalers.
What could go wrong: This is a Phase 3 trial, but results may not show significant benefit over placebo. Side effects or lack of efficacy could limit its use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

asthma chronic asthma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASTHMA

Contacts and locations

Locations

Affiliated Hospital of Jiangsu University
NOT_YET_RECRUITING

Nanjing, Jiangsu, 210029, China
Affiliated Hospital of Jining Medical Hospital
NOT_YET_RECRUITING

Jining, Shandong, 272000, China
Anhui Chest Hoispital
NOT_YET_RECRUITING

Hefei, Anhui, 230022, China
Baotou Central Hospital
NOT_YET_RECRUITING

Baotou, Inner Mongolia, 014040, China
Beijing No.6 Hospital
NOT_YET_RECRUITING

Beijing, Beijing Municipality, 100007, China
Cangzhou Hospital of Integrated TCM-WM·Hebei
NOT_YET_RECRUITING

Cangzhou, Hebei, 061000, China
Central Hospital Affiliated to Shandong First Medical University
NOT_YET_RECRUITING

Jinan, Shandong, 250000, China
Changsha Central Hospital
NOT_YET_RECRUITING

Changsha, Hunan, 410000, China
Chengdu Fifth People's Hospital
NOT_YET_RECRUITING

Chengdu, Sichuan, 611130, China
Chifeng Municipal Hospital
NOT_YET_RECRUITING

Chifeng, Inner Mongolia, 024099, China
Da Qing Long Nan Hospital
NOT_YET_RECRUITING

Daqing, Heilongjiang, 163453, China
Dalian Municipal Central Hospital
NOT_YET_RECRUITING

Dalian, Liaoning, 116021, China
Enshi Tujia and Miao Autonomous Prefecture Central Hospital
NOT_YET_RECRUITING

Enshi, Hubei, 445000, China
First Affiliated Hospital of Xinjiang Medical University
NOT_YET_RECRUITING

Ürümqi, Xinjiang, 830000, China
Fudan University Affiliated Zhongshan Hospital
NOT_YET_RECRUITING

Shanghai, Shanghai Municipality, 200032, China
Gansu Provincial Hospital
NOT_YET_RECRUITING

Gansu, Lanzhou, 730000, China
Genertec Liaoyou Gem Flower Hospital
NOT_YET_RECRUITING

Panjin, Liaoning, 124000, China
Guangdong Provincial Hospital of Traditional Chinese Medicine
NOT_YET_RECRUITING

Guangzhou, Guangdong, 510120, China
Guangzhou First People's Hospital
NOT_YET_RECRUITING

Guangzhou, Guangdong, 510180, China
Guilin People'S Hospital
NOT_YET_RECRUITING

Guilin, Guangxi, 541002, China
Guizhou Provincial People's Hospital
NOT_YET_RECRUITING

Guiyang, Guizhou, 550000, China
Henan Provincial People's Hospital
NOT_YET_RECRUITING

Zhengzhou, Henan, 450003, China
Heze Municipal Hospital
NOT_YET_RECRUITING

Heze, Shandong, 274031, China
Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University)
NOT_YET_RECRUITING

Changsha, Hunan, 410021, China
Inner Mongolia Autonomous Region People's Hospital
NOT_YET_RECRUITING

Hohhot, Inner Mongolia, 100017, China
Jiangsu University Affiliated Hospital
NOT_YET_RECRUITING

Zhenjiang, Jiangsu, 212001, China
Jilin University Second Hospital
NOT_YET_RECRUITING

Changchun, Jilin, 130000, China
Jincheng General Hospital
NOT_YET_RECRUITING

Jincheng, Shanxi, 48000, China
Jinhua Municipal Central Hospital
NOT_YET_RECRUITING

Jinhua, Zhejiang, 321000, China
Loudi central hospital
NOT_YET_RECRUITING

Loudi, Hunan, 417000, China
Lu'an People's Hospital of Anhui Province
NOT_YET_RECRUITING

Lu'an, Anhui, 237000, China
Luo Yang Dong Fang People's Hospital
NOT_YET_RECRUITING

Luoyang, Henan, 471003, China
No.215 Hospital of Shaanxi Nuclear Industry
NOT_YET_RECRUITING

Xianyang, Shanxi, 712000, China
Northern Jiangsu People's Hospital
NOT_YET_RECRUITING

Yangzhou, Jiangsu, 225001, China
Peking University First Hospital
NOT_YET_RECRUITING

Beijing, Beijing Municipality, 100000, China
People's Hospital of Xinjiang Uygur Autonomous Region
NOT_YET_RECRUITING

Ürümqi, Xinjiang, 830000, China
People's Liberation Army North Theater General Hospital
NOT_YET_RECRUITING

Shenyang, Liaoning, 130012, China
Pingxiang People's Hospital
NOT_YET_RECRUITING

Pingxiang, Jiangxi, 337055, China
Rui Jin Hospital Shanghai Jiaotong University School of Medical
NOT_YET_RECRUITING

Shanghai, Shanghai Municipality, 200025, China
Shanghai General Hospital
NOT_YET_RECRUITING

Shanghai, Shanghai Municipality, 200080, China
Shanghai Pudong Hospital, Fudan University Affiliated Pudong Medical Center
NOT_YET_RECRUITING

Shanghai, Shanghai Municipality, 200120, China
Shanxi Bethune Hospital
NOT_YET_RECRUITING

Taiyuan, Shanxi, 030032, China
Shengjing Hospital affiliated to China Medical University
NOT_YET_RECRUITING

Shenyang, Liaoning, 110000, China
Shengjing Hospital of China Medical University
NOT_YET_RECRUITING

Shenyang, Liaoning, 110000, China
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
NOT_YET_RECRUITING

Chengdu, Sichuan, 610072, China
Suining Central Hospital
NOT_YET_RECRUITING

Suining, Sichuan, 629000, China
Taizhou Central Hospital(Taizhou University Hospital)
NOT_YET_RECRUITING

Taizhou, Zhejiang, 318000, China
The 2nd School of Medicine,WMU/The 2nd Affiliated Hospital and Yuying Children's Hospital of WMU
NOT_YET_RECRUITING

Wenzhou, Zhejiang, 325000, China
The Affiliated Hospital of Inner Mongolia Medical University
NOT_YET_RECRUITING

Hohhot, Inner Mongolia, 100000, China
The Affiliated Hospital of Medical University
NOT_YET_RECRUITING

Guilin, Guangxi, 541000, China
The Affiliated Hospital of Qingdao University
NOT_YET_RECRUITING

Qingdao, Shandong, 266003, China
The Affiliated Hospital of Xuzhou Medical University
NOT_YET_RECRUITING

Xuzhou, Jiangsu, 221000, China
The Central Hospital of Wuhan
NOT_YET_RECRUITING

Wuhan, Hubei, 430000, China
The Eighth Afliated Hospital of Southern Medical University The First people's Hospital of Shunde
NOT_YET_RECRUITING

Foshan, Guangdong, 528300, China
The First Affiliated Hospital of Anhui Medical University
NOT_YET_RECRUITING

Hefei, Anhui, 230022, China
The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology
NOT_YET_RECRUITING

Baotou, Inner Mongolia, 14000, China
The First Affiliated Hospital of Guangzhou Medical University
RECRUITING

Guangzhou, Guangdong, 510000, China
The First Affiliated Hospital of Hainan Medical University
NOT_YET_RECRUITING

Haikou, Hainan, 570102, China
The First Affiliated Hospital of Nanchang University
NOT_YET_RECRUITING

Nanchang, Jiangxi, 330038, China
The First Affiliated Hospital of Ningbo University
NOT_YET_RECRUITING

Ningbo, Zhejiang, 315020, China
The First Affiliated Hospital of Shihezi University
NOT_YET_RECRUITING

Shihezi, Xinjiang, 832008, China
The First Affiliated Hospital of Xi'an Jiaotong University
NOT_YET_RECRUITING

Xi'an, Shaanxi, 710000, China
The First Affiliated Hospital of Xi'an Medical Universi
NOT_YET_RECRUITING

Xi'an, Shaanxi, 710000, China
The First Affiliated Hospital of Xiamen University
NOT_YET_RECRUITING

Xiamen, Fujian, 361000, China
The First Affiliated of Kumming Medical University
NOT_YET_RECRUITING

Kunming, Yunnan, 652700, China
The First Hospital of Jlin University
NOT_YET_RECRUITING

Changchun, Jilin, 130000, China
The First Hospital of Lanzhou University
NOT_YET_RECRUITING

Lanzhou, Gansu, 730000, China
The First Hospital of Qiqihar
NOT_YET_RECRUITING

Qiqihar, Heilongjiang, 161000, China
The First People's Hospital of Yinchuan
NOT_YET_RECRUITING

Yinchuan, Ningxia, 750001, China
The First People's Hospital of Yunnan Province
NOT_YET_RECRUITING

Kunming, Yunnan, 650000, China
The Fourth Affiliated Hospital of Harbin Medical University
NOT_YET_RECRUITING

Harbin, Heilongjiang, 150001, China
The People's Hospital of Anyang
NOT_YET_RECRUITING

Anyang, Henan, 455099, China
The People's Hospital of Bozhou
NOT_YET_RECRUITING

Bozhou, Anhui, 236000, China
The People's Hospital of Yuyao
NOT_YET_RECRUITING

Yuyao, Zhejaing, 315400, China
The Second Affiliated Hospital of Shandong First Medical University
NOT_YET_RECRUITING

Tai’an, Shandong, 271000, China
The Second Affiliated Hospital of Xi'an Jiaotong University
NOT_YET_RECRUITING

Xi'an, Shaanxi, 710000, China
The Second Hospital & Clinical Medical School,Lanzhou University
NOT_YET_RECRUITING

Lanzhou, Gansu, 730000, China
The Second People's Hospital of Jiaozuo City
NOT_YET_RECRUITING

Jiaozuo, Henan, 454001, China
The Second Xiangya Hospital of Central South University
NOT_YET_RECRUITING

Changsha, Hunan, 410011, China
Third People's Hospital of Huizhou
NOT_YET_RECRUITING

Huizhou, Guangdong, 516002, China
Tianjin 4th Center Hospital
NOT_YET_RECRUITING

Tianjin, Tianjin Municipality, 300140, China
Tianjin Medical University General Hospital
NOT_YET_RECRUITING

Tianjin, Tianjin Municipality, 300052, China
Tongling People's Hospital
NOT_YET_RECRUITING

Tongling, Anhui, 244000, China
Weifang NO.2 People's Hospital
NOT_YET_RECRUITING

Weifang, Shandong, 261041, China
West China Hospital, Sichuan University
NOT_YET_RECRUITING

Chengdu, Sichuan, 610000, China
Wusong Central Hospital, Baoshan District, Shanghai
RECRUITING

Shanghai, Shanghai Municipality, 200940, China
Wuxi Second People's Hospital
NOT_YET_RECRUITING

Wuxi, Jiangsu, 214002, China
Xi'an International Medical Center Hospital
NOT_YET_RECRUITING

Xi'an, Shaanxi, 710000, China
Xi'an People's Hospital (Xi'an Fourth Hospital)
NOT_YET_RECRUITING

Xi'an, Shaanxi, 710004, China
Xingtai People's Hospital
NOT_YET_RECRUITING

Xingtai, Hebei, 054001, China
Xinxiang Central Hospital
NOT_YET_RECRUITING

Xinxiang, Henan, 453000, China
Xuzhou Central Hospital
NOT_YET_RECRUITING

Xuzhou, Jiangsu, 221000, China
Yangquan Coal Industry Group General Hospital
NOT_YET_RECRUITING

Yangquan, Shanxi, 45000, China
Yantai Yuhuangding Hospital
NOT_YET_RECRUITING

Yantai, Shandong, 264099, China
Yibin Second People's Hospital
NOT_YET_RECRUITING

Yibin, Sichuan, 644000, China
Zaozhuang Municipal Hospital
NOT_YET_RECRUITING

Zaozhuang, Shandong, 277000, China
Zhangzhou Municipal Hospital of Fujian
NOT_YET_RECRUITING

Zhangzhou, Fujian, 363000, China
Zhengzhou Central Hospital
NOT_YET_RECRUITING

Zhengzhou, Henan, 450007, China
Zhongshan City People's Hospital
NOT_YET_RECRUITING

Zhongshan, Guangdong, 528403, China
Zhoukou Central hospital
NOT_YET_RECRUITING

Zhoukou, Henan, 466000, China
Zibo Central Hospital
NOT_YET_RECRUITING

Zibo, Shandong, 250036, China

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