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New asthma drug aims to clear mucus and protect airways

NCT ID NCT06979323

Recruiting now Disease control Sponsor: GlaxoSmithKline Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 1 time

Summary

This study tests a drug called depemokimab in 150 adults with severe asthma caused by a specific type of inflammation. The goal is to see if the drug can reduce mucus plugs and airway thickening in the lungs. Participants will receive the drug and have lung scans and breathing tests over 52 weeks.

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Conditions

The condition(s) this trial relates to.

asthma T2-high asthma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASTHMA

Contacts and locations

Locations

  • GSK Investigational Site

    RECRUITING

    Brooksville, Florida, 34613, United States

  • GSK Investigational Site

    RECRUITING

    Plantation, Florida, 33324, United States

  • GSK Investigational Site

    RECRUITING

    Kansas City, Kansas, 66160, United States

  • GSK Investigational Site

    RECRUITING

    St Louis, Missouri, 63110, United States

  • GSK Investigational Site

    RECRUITING

    New Brunswick, New Jersey, 08901, United States

  • GSK Investigational Site

    RECRUITING

    New York, New York, 10029, United States

  • GSK Investigational Site

    RECRUITING

    DuBois, Pennsylvania, 15801, United States

  • GSK Investigational Site

    RECRUITING

    Philadelphia, Pennsylvania, 19140-5103, United States

  • GSK Investigational Site

    COMPLETED

    McKinney, Texas, 75069, United States

  • GSK Investigational Site

    RECRUITING

    Mechelen, 2800, Belgium

  • GSK Investigational Site

    RECRUITING

    Namur, 5101, Belgium

  • GSK Investigational Site

    RECRUITING

    Ajax, Ontario, L1S 2J5, Canada

  • GSK Investigational Site

    RECRUITING

    Hamilton, Ontario, L8N 3Z5, Canada

  • GSK Investigational Site

    RECRUITING

    London, Ontario, N6A 5A5, Canada

  • GSK Investigational Site

    RECRUITING

    Guangzhou, 510163, China

  • GSK Investigational Site

    RECRUITING

    Shanghai, 200080, China

  • GSK Investigational Site

    RECRUITING

    Tianjin, 300052, China

  • GSK Investigational Site

    RECRUITING

    Brest, 29200, France

  • GSK Investigational Site

    RECRUITING

    Créteil, 94010, France

  • GSK Investigational Site

    RECRUITING

    La Tronche, 38700, France

  • GSK Investigational Site

    RECRUITING

    Pessac, 33604, France

  • GSK Investigational Site

    RECRUITING

    Reims, 51092, France

  • GSK Investigational Site

    RECRUITING

    Bonn, 53127, Germany

  • GSK Investigational Site

    RECRUITING

    Frankfurt, 60389, Germany

  • GSK Investigational Site

    RECRUITING

    Athens, 106 76, Greece

  • GSK Investigational Site

    RECRUITING

    Athens, 115 21, Greece

  • GSK Investigational Site

    RECRUITING

    Heraklion, Greece

  • GSK Investigational Site

    RECRUITING

    Ioannina, 45500, Greece

  • GSK Investigational Site

    RECRUITING

    Thessaloniki, Greece

  • GSK Investigational Site

    RECRUITING

    Catania, Italy

  • GSK Investigational Site

    RECRUITING

    Genova, 16132, Italy

  • GSK Investigational Site

    RECRUITING

    Roma, 00168, Italy

  • GSK Investigational Site

    RECRUITING

    Rozzano, 20089, Italy

  • GSK Investigational Site

    RECRUITING

    Jeonju, 54907, South Korea

  • GSK Investigational Site

    RECRUITING

    Seoul, 03080, South Korea

  • GSK Investigational Site

    RECRUITING

    Seoul, 03722, South Korea

  • GSK Investigational Site

    RECRUITING

    Seoul, 06351, South Korea

  • GSK Investigational Site

    RECRUITING

    Barcelona, Spain

  • GSK Investigational Site

    RECRUITING

    Barcelona, Spain

  • GSK Investigational Site

    RECRUITING

    Benalmádena, 29631, Spain

  • GSK Investigational Site

    RECRUITING

    Madrid, 28031, Spain

  • GSK Investigational Site

    RECRUITING

    Palma de Mallorca, 070120, Spain

  • GSK Investigational Site

    RECRUITING

    Santander, 39008, Spain

  • GSK Investigational Site

    RECRUITING

    Kaohsiung City, Taiwan

  • GSK Investigational Site

    RECRUITING

    Taichung, 407, Taiwan

  • GSK Investigational Site

    RECRUITING

    Taipei, 100, Taiwan

  • GSK Investigational Site

    RECRUITING

    Bradford, BD9 6RJ, United Kingdom

  • GSK Investigational Site

    RECRUITING

    London, SE1 9RT, United Kingdom

  • GSK Investigational Site

    RECRUITING

    London, W6 8RF, United Kingdom

  • GSK Investigational Site

    RECRUITING

    Southampton, SO16 6YD, United Kingdom

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