Mucus mystery: new study aims to uncover role of airway blockages in lung disease

NCT ID NCT06858748

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This observational study will use CT scans to measure mucus plugging in the airways of people with asthma, COPD, or chronic cough, and compare them to healthy volunteers. Researchers hope to understand how mucus changes over time and find biomarkers that could guide treatment. The study will enroll 240 adults and 50 children with lung disease, plus 100 healthy adults, and follow them for two years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help doctors better understand how mucus affects lung diseases and guide more personalized treatments.

What could go wrong

This is an observational study, not a treatment trial. It will not directly test any new therapy, and results may take years to influence clinical practice.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

asthma Chronic Cough chronic obstructive pulmonary disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Quebec Heart and Lung Institute - Laval University

    NOT_YET_RECRUITING

    Québec, Quebec, G1V 4G5, Canada

    Contact Email: •••••@•••••

  • Robarts Research Institute

    NOT_YET_RECRUITING

    London, Ontario, N6A 5B7, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St. Joseph's Healthcare Hamilton

    RECRUITING

    Hamilton, Ontario, L8N 4A6, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St. Paul's Hospital

    NOT_YET_RECRUITING

    Vancouver, British Columbia, V6Z 1Y6, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Ottawa Hospital

    NOT_YET_RECRUITING

    Ottawa, Ontario, K1H 8L6, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Université de Sherbrooke

    NOT_YET_RECRUITING

    Sherbrooke, Quebec, J1H 5N4, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••