Tiny lungs, big secrets: microbiome study aims to unlock severe infant asthma

NCT ID NCT06044051

Recruiting now Knowledge-focused Sponsor: University Hospital, Rouen Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at the bacteria (microbiomes) in the airways of infants under 2 years old with severe asthma. Researchers will collect blood, nasal swabs, and sputum samples to understand how these microbiomes relate to the disease. The goal is to find new ways to improve care and discover potential treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could point toward new treatments for severe infant asthma, such as using azithromycin as an immune modulator.
What could go wrong: This is an observational study, not a treatment trial. It is small (100 infants) and early-stage, so findings may not lead directly to new therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

asthma childhood onset asthma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASTHMA ASTHMA IN CHILDREN

Contacts and locations

Locations

Rouen University Hospital
RECRUITING

Rouen, France

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