ASTHMA IN CHILDREN

This study aims to see if a program called PRAGMATIC-S can improve asthma control in children aged 4 to 12. The program helps doctors and schools work together to follow asthma care guidelines. About 420 children with persistent or uncontrolled asthma will take part. The goal is …

This study tests whether a soy supplement (isoflavones) can reduce asthma risk in infants who have a genetic tendency for inflammation. 65 babies under 12 months old will receive either soy or a placebo mixed into food for 7 months. Researchers will track wheezing episodes and lu…

This study tests a program called TEACH-ER that helps children with asthma after they leave the emergency room. It includes education, a virtual doctor visit within a week, and follow-up video calls to support medication use and management. The goal is to reduce future asthma att…

This study tests two school-based programs to help children ages 5-12 from low-income communities in Colorado better manage their asthma. The goal is to reduce asthma attacks and missed school days by having school nurses and navigators coordinate care with doctors and community …

This study is for children aged 5 to nearly 17 who were admitted to the intensive care unit for asthma. Researchers want to see if a personalized asthma navigator program, which helps families manage asthma at home, can reduce future emergency visits. The program will be tested w…

This study tests whether a smartphone app and digital sensors can help families better manage their child's asthma. About 80 parent-child pairs will either get the app with extra support from an asthma coordinator or just the app alone. The goal is to see if this approach is prac…

This study tests whether a daily soluble fiber drink (inulin) can improve asthma control in children ages 6-17. Researchers will measure changes in gut bacteria, nasal inflammation, and asthma symptoms over 4-6 weeks. The goal is to see if adjusting diet can help manage asthma, n…

This study looks at whether school-based health centers can improve asthma care for children in underserved communities. About 400 children with uncontrolled asthma will receive guideline-based assessments, preventive medication, and directly observed therapy at school. The goal …

This study tests whether using simple insecticidal bait to reduce cockroaches in the home can improve asthma symptoms in children aged 5-17. Researchers will track symptom days, hospital visits, and asthma control over 12 months. The goal is to find a low-cost, low-toxicity way t…

This study looks at whether extra support from an asthma navigator can help children aged 4 to 12 avoid another hospital stay after being treated for an asthma attack. About 340 families will take part, with half getting the usual care and half also getting a navigator to help ma…

This study tests a program called CHAMPION that helps children with both asthma and overweight. It compares doing the program in-person versus online to see which works better. About 500 children aged 4-17 with asthma and a high BMI will take part. The goal is to improve their we…

This study looks at whether two easy, non-invasive tests—a breath test (FeNO) and a blood test (eosinophils)—can accurately diagnose asthma in children aged 6 to 17. Currently, diagnosing asthma often requires complex hospital-based tests. The goal is to see if these simpler test…

This study looks at whether measuring inflammation in the breath and blood can help prioritize who gets lung tests first when asthma is suspected. Researchers will include 1,500 people aged 6 and older who were referred by their primary care doctor. The goal is to see if this app…

This study tests whether a smartphone app can help parents reduce their young children's exposure to second-hand smoke. About 160 children under 6 who live with a smoking parent will take part. The goal is to lower the children's urine cotinine levels, a marker of smoke exposure,…

This study tests whether a new way of talking to teens about their asthma can improve their quality of life. About 98 teenagers aged 12-18 with asthma will be randomly assigned to either a special consultation focused on their confidence in managing asthma, or a standard appointm…

This study tests whether a short-term therapy for depression, called Enhanced IPT-B, can help Black mothers of children with asthma feel better and possibly improve their child's asthma. About 60 mothers will receive either the therapy or standard care plus extra support. The goa…

This study looks at whether a new, step-by-step care plan for children having mild to moderate asthma attacks can improve how quickly they get the right treatment. The plan is designed to help doctors and nurses work together better. About 249 children and their healthcare provid…

This study looks at the bacteria living in the airways of infants under 2 years old with severe asthma. Researchers want to understand how these bacteria differ from normal and how they relate to the immune system. The goal is to find new ways to treat severe asthma in babies. Th…

This study looks at how well hospitals follow the latest GINA 2025 guidelines when treating children (ages 6-17) having asthma attacks. Researchers will check if using these guidelines leads to better diagnosis, treatment, and follow-up care. The goal is to improve care for kids …

This study looks at ways to help doctors use a preferred asthma treatment called SMART for children with moderate to severe asthma. Researchers will test tools like electronic reminders and education to see if they increase how often doctors prescribe SMART. About 18 clinics and …

This study looks at how to help doctors prescribe a newer, more effective asthma treatment called SMART for children ages 5 to 18 with moderate to severe asthma. Researchers will test different support strategies, like community health workers and nurse care managers, to see whic…

This study tests a wearable stethoscope patch that listens to breath sounds in children aged 6-17 with asthma who are in the hospital for an attack. The patch is worn on the chest and back for up to 8 hours to detect wheezing. Researchers want to see if the device can reliably ca…

This study looks at how the amount of sleep urban children with asthma get affects their immune system and breathing. Researchers will test 204 children aged 7-11 by changing their sleep times and measuring immune markers and lung function. The goal is to understand why city kids…

This study looks at how certain medicines act in the bodies of children and young adults under 21. Researchers want to find the safest and most effective doses for these age groups. Participants are already taking these drugs as part of their regular care, or have had a recent CO…