Pregnancy disorder

This phase 2 trial tests a combination of two immunotherapy drugs, domvanalimab and zimberelimab, in people with five types of advanced rare cancers (peritoneal mesothelioma, gestational trophoblastic tumor, anaplastic thyroid carcinoma, neuroendocrine tumors, and thymic carcinom…

This phase 2 trial is testing a combination of two immunotherapy drugs, nivolumab and ipilimumab, in 798 people with over 50 types of rare cancers. The goal is to see if these drugs can shrink tumors by helping the immune system attack cancer cells. Participants receive the drugs…

This study tests if a new growth hormone medicine (somapacitan) given once a week works as well as the standard daily growth hormone (Norditropin) for children who are very short due to being born small, or having Turner syndrome, Noonan syndrome, or unknown causes. About 412 chi…

This study tests whether adding a specially trained doula, along with home blood pressure and weight monitoring, can improve blood pressure in women who had high blood pressure during pregnancy. About 454 women will be randomly assigned to usual care or the doula program. The goa…

This study tests a new once-weekly growth hormone medicine (somapacitan) against a daily one (Norditropin) in 62 children born small who remain short. The goal is to see if the weekly shot works as well and is safe. Children receive injections either once a week or once a day for…

This study tests whether an AI-based counseling program on a smartphone can help women with gestational diabetes manage their condition. 80 pregnant women will either get standard nutrition advice or AI-powered guidance. The goal is to see if the AI approach leads to healthier bi…

This study looks at whether allowing a slightly higher blood sugar range (70-110 mg/dL) during labor in mothers with diabetes can reduce the number of newborns with low blood sugar. Researchers will compare this approach to standard care in 169 pregnant women planning a vaginal d…

This study looked at a fetal surgery called fetoscopic laser photocoagulation (FLP) to treat vasa previa, a condition where fetal blood vessels cover the womb opening, making vaginal delivery dangerous. The goal was to seal off these vessels to prevent bleeding and allow a safer …

This study looks at the best way to control blood sugar in pregnant women with diabetes who receive steroids to help their baby's lungs develop before a possible early birth. About 120 women will be randomly assigned to one of three insulin strategies. The goal is to find which a…

This study tests whether giving pregnant women a daily vitamin B12 supplement (50 micrograms) from early pregnancy until six months after birth helps their children grow and think better. Researchers are enrolling 800 pregnant women in Nepal who are at risk of low B12 levels. The…

This study tests whether giving melatonin to pregnant women with a severe form of fetal growth restriction can help their babies. The trial will involve 240 women who will take either melatonin or a placebo nightly. Researchers will track baby growth, pregnancy length, and newbor…

This study tests a special care program for pregnant women with sickle cell disease in Ghana. A team of obstetric and sickle cell experts works together to prevent complications and reduce deaths. Researchers will track 500 women to see if this low-cost approach improves survival…

This study tests whether having more frequent checkups with an obstetric provider or a study nurse during the first year after childbirth can help women with high blood pressure or diabetes manage their health better. One hundred women with Medicaid insurance who had these condit…

This study looks at the best time to start medication for gestational diabetes during pregnancy. About 416 pregnant women with the condition are randomly assigned to start medicine when 20% or 40% of their blood sugar readings are too high. The goal is to see which approach leads…

This study tests whether adding Moringa leaf powder to standard iron pills can better improve hemoglobin levels in pregnant women with iron deficiency anemia. About 59 women in their third trimester will take either Moringa capsules plus iron or iron alone for 60 days. Researcher…

This study tests whether a specially designed app can help women who had high blood pressure or diabetes during pregnancy get the recommended heart check-ups after giving birth. About 400 women from Oslo University Hospital will either use the app or receive standard care. The go…

This study tests whether group prenatal care, where women with diabetes meet together with a healthcare provider, works better than standard one-on-one visits. Researchers will track blood sugar levels and weight after delivery in 117 pregnant women with type 2 or gestational dia…

This study tests an artificial intelligence (AI) tool on a smartphone to help women with gestational diabetes monitor their blood sugar and receive education. About 100 pregnant women will use the AI system to track their glucose levels at home and get feedback. The goal is to se…

This study tests whether intensive dietary counseling from a dietitian can help women with gestational diabetes control blood sugar without needing insulin. 214 women will be randomly assigned to either intensive nutrition support or standard care. The main goal is to see if more…

This study tests whether hydroxytyrosol, a natural antioxidant from olives, can improve blood vessel function in pregnant women with high blood pressure. Fifty-two women will take either the supplement or a placebo for 4 weeks. Researchers will measure changes in blood markers an…

This study tests whether myo-inositol, an oral dietary supplement, can help pregnant women with gestational diabetes control their blood sugar without needing insulin shots. About 1,080 women with newly diagnosed gestational diabetes will receive either myo-inositol or a placebo …

This study aimed to see if the drug tolvaptan could help infants with a severe form of polycystic kidney disease (ARPKD) avoid needing dialysis or a kidney transplant in their first year of life. The trial was planned for babies between 28 days and 12 weeks old, but it was withdr…

This study tests whether sending text message reminders and education to pregnant women with diabetes helps them follow their care plan—like keeping appointments, tracking blood sugar, and taking medications. About 185 participants will be randomly assigned to receive texts or st…

This study looks at whether giving pasteurized donor milk instead of formula to newborns who need extra feeding helps mothers breastfeed longer. It includes babies born small, late preterm, or to mothers with diabetes. About 112 infants will be randomly assigned to receive donor …

This study looks at whether a daily probiotic supplement can improve blood sugar control and limit weight gain in pregnant women who are overweight. About 84 women in early pregnancy will take the supplement or a placebo. The goal is to see if probiotics can help manage metabolic…

This study tests a new growth hormone medicine called somapacitan, given once a week, in 47 children who are very short due to being born small for gestational age, or having Turner syndrome, Noonan syndrome, or idiopathic short stature. The main goal is to see if it is safe and …

This study tests a program that connects pregnant women with opioid use disorder to a team of doctors, peer supporters, and community resources like doulas and home visiting. The goal is to improve treatment during pregnancy and reduce the need for medication in newborns experien…

This study tests whether intensive blood pressure treatment after childbirth can improve women's long-term heart health. Researchers will enroll 60 women who had high blood pressure during pregnancy and give them nifedipine to keep their BP below 140/90 mmHg. The goal is to see i…

This study tests whether giving blood pressure medication to women after childbirth can prevent hospital readmissions and reduce severe high blood pressure. About 300 women with preeclampsia will either receive standard care or start blood pressure drugs like labetalol or nifedip…

This study tests whether providing 10 healthy, home-delivered meals per week plus brief weekly coaching can help pregnant women with overweight or obesity avoid gaining too much weight. Researchers will track weight changes and also measure food security and stress. The study is …

This study tests whether women with high-risk pregnancies can safely monitor their baby's heart rate and their own blood pressure from home instead of going to the hospital. About 450 participants across four European hospitals will use certified home devices, with data reviewed …

This study compares two guided diets for overweight pregnant women diagnosed with gestational diabetes: one moderately low in carbohydrates and another high in plant-based protein with Nordic foods. Over 42 participants, researchers track blood sugar levels using continuous monit…

This study tests whether a wireless monitor worn for 24 hours after an emergency C-section can alert doctors when a new mother's vital signs become dangerous. Over 3,000 women in Uganda will wear the device, which sends alerts if heart rate, blood pressure, or other readings fall…

This study tests a new urine test called CercaTest™ Red to predict preeclampsia in pregnant women who show signs of the condition. Preeclampsia is a serious complication involving high blood pressure and organ damage. The test is designed to be used at the point of care, giving q…

This study is testing whether a continuous glucose monitor (CGM) worn on the arm for 14 days can replace the standard oral glucose tolerance test (OGTT) for women who had gestational diabetes. Many women find the OGTT burdensome and skip it, missing a chance to catch lingering bl…

This study tests whether giving pregnant women a heart ultrasound during routine check-ups can catch hidden heart problems and reduce risks like death, heart failure, or low baby health scores. About 9,000 women in Nepal will be randomly assigned to receive the ultrasound or stan…

This study looks at whether 3D color ultrasound can accurately detect how deeply the placenta has grown into the uterine wall (placenta accreta spectrum) in pregnant women. Researchers will compare ultrasound images taken before delivery with what doctors see during C-section. Th…

This study will test a telehealth group prenatal care program called Centering HER in 72 low-income, predominantly Black pregnant women in Kansas who are at moderate or high risk for preeclampsia. Participants will receive routine care plus seven doula-led virtual group sessions,…

This study tests whether using a smartphone app and a home blood pressure monitor can help prevent heart disease in women who had high blood pressure during pregnancy. 120 women who gave birth at Northwestern Memorial Hospital will use these digital tools for 12 months after deli…

This study tests a community-based program called Thriving Hearts across ten North Carolina counties. Pregnant individuals at risk for hypertensive disorders receive a care kit with a home blood pressure monitor and stress management tools, plus extra support from healthcare prov…

This study tests whether providing money specifically for healthy foods during pregnancy helps minority and rural women in Arkansas avoid gaining too much weight. About 280 pregnant women will either receive standard nutrition advice or that advice plus funds to buy recommended h…

This study tests whether providing fresh meals, health coaching, and education to high-risk pregnant women can reduce the chance of developing gestational diabetes, high blood pressure, or preeclampsia. 69 women in Milwaukee are randomly assigned to either receive the program or …

This study in Addis Ababa, Ethiopia, tests whether giving protein supplements only to pregnant women who are undernourished can prevent problems like low birth weight and stillbirth. Over 6,700 pregnant women are randomly assigned to receive supplements either universally or only…

This study tests whether a weight loss program for overweight or obese women (and their partners) before pregnancy can reduce the risk of their child becoming overweight. 240 couples are randomly assigned to either a very low-calorie diet and counseling or no intervention. The ma…

This trial tests an online program to help women who had gestational diabetes get the recommended diabetes screening and lifestyle programs after giving birth. The program includes standard health information plus optional interactive components like values reflection and persona…

This study tests whether screening pregnant women for malaria with a highly sensitive rapid test during the first trimester, followed by treatment if positive, can improve newborn health. Over 2,000 women in malaria-prone areas will be compared to those receiving usual care. The …

This study tests whether pregnant women who eat two eggs daily have babies with longer birth lengths and better development. Researchers in Rwanda are giving eggs to some women and comparing them to those eating their usual diet. The goal is to see if this simple, affordable food…

This study tests whether helping women with overweight or obesity adopt a healthy lifestyle before and during pregnancy can reduce the risk of their children developing obesity. About 360 women planning pregnancy will either receive a tailored program including a low-calorie diet…

This study tests a mobile app called Next4You designed for teens aged 16-19 in California's foster care system. The app offers short lessons on communication, relationships, sexual health, and wellness over four weeks. Researchers want to see if it helps teens avoid unintended pr…

This study looks at whether combining high-intensity exercise with time-restricted eating before and during pregnancy can lower the risk of high blood sugar (gestational diabetes). Researchers will track 167 women who are planning to become pregnant and have certain risk factors,…

This study tests whether giving the antibiotic azithromycin to pregnant women and their babies during routine care can prevent stillbirths and infant deaths in Mali, a country with very high infant mortality. Over 99,000 participants are involved in this large, placebo-controlled…

This study looks at whether a community-based program focused on healthy eating and exercise during and after pregnancy can lower the chances of obesity and type 2 diabetes in mothers and their children. About 1,000 pregnant women in urban areas will take part. The goal is to see…

This phase 4 trial tests whether taking metformin daily before 20 weeks of pregnancy can reduce the risk of high blood pressure disorders, like preeclampsia, in pregnant women with type 1 diabetes. About 60 women will receive either metformin plus standard care or standard care a…

This study tests whether a 3-year program of diet advice, exercise coaching, and behavior support can prevent type 2 diabetes in 800 women who had gestational diabetes. Participants will receive personalized meal plans and regular sessions with dietitians and exercise instructors…

This study investigates how aspirin can prevent preeclampsia, a serious pregnancy condition, in first-time mothers at high risk. Researchers will compare biological changes in 200 women with low or high risk, some taking aspirin and some not. The goal is to understand how aspirin…

This pilot study tests whether remote monitoring and guideline-directed therapy can prevent heart dysfunction in African American women who had preeclampsia. Twenty participants will use a tablet, blood pressure cuff, and scale at home for three months after delivery. The goal is…

This study tests whether taking riboflavin (vitamin B2) and a form of folate can prevent high blood pressure in pregnant women who have a specific gene variant (MTHFR TT). About 2250 women in their first trimester are being recruited. Those with the gene variant will receive the …

This study tests whether taking L-citrulline, a natural amino acid supplement, daily from early pregnancy can prevent high blood pressure conditions like preeclampsia in women expecting their first child. About 338 healthy first-time mothers between 12-16 weeks pregnant will rece…

This study tests whether starting nutritional counseling early in pregnancy can improve blood sugar control in women at risk for gestational diabetes. 150 pregnant women will receive either standard care or one-on-one sessions with a dietitian, plus videos and phone support. The …

This study tests whether an 8-week phone-based mindfulness program can reduce stress and blood pressure in 150 pregnant women at risk for hypertensive disorders. Participants will complete daily surveys and wear biosensors to track stress and heart activity. The goal is to see if…

This study looks at whether progressive muscle relaxation and finger grip exercises can lower stress, anxiety, and fatigue while improving sleep in pregnant women with preeclampsia. About 90 women will be split into three groups: one doing relaxation exercises, one doing finger g…

This study tests whether a physical activity program can help pregnant people with symptoms of depression or anxiety feel better. 88 participants will be given a step goal and wear an activity tracker. The program includes weekly reminders and motivational coaching every two week…

This study tests whether a prenatal yoga app called Down Dog can help pregnant African American women feel better mentally and physically. Over 12 weeks, 50 first-time mothers will use the app at home, wear a fitness tracker, and complete surveys. The goal is to see if the app is…

This study tests a program called Well-Mama, where community doulas use a checklist to help pregnant women get better care. About 576 pregnant women who are uninsured or on Medicaid will either receive standard care or standard care plus the Well-Mama support. The goal is to see …

This study looks at whether eating three dates each morning can help reduce vomiting and improve hemoglobin levels in pregnant women experiencing morning sickness. Forty pregnant women will be randomly assigned to eat dates, take standard anti-nausea medication, or follow dietary…

This study tests a group prenatal care program called EleVATE GC for African-American women at high risk for postpartum depression. The program aims to reduce depression, preterm birth, and low birthweight by providing support and addressing stress. Researchers will compare outco…

This study tests whether a mobile app called SugarMoms, which provides education and counseling, can help pregnant women with gestational diabetes improve their self-management skills and confidence. About 94 women will be split into two groups: one using the app plus standard ca…

This study tests whether a simplified behavioral relaxation program can improve sleep in pregnant women with insomnia. Twenty women in their second or third trimester will receive coaching calls and sleep hygiene tips. The goal is to see if this approach helps them fall asleep fa…

This pilot study tests whether giving calcium carbonate to pregnant women during labor induction can shorten the time needed and reduce the need for C-sections. Researchers will compare 250 women who receive calcium with a historical control group. The goal is to see if this simp…

This study follows over 4,000 women who were tracked during their first pregnancy to see how pregnancy complications like high blood pressure or diabetes relate to future heart disease. Researchers will check for conditions like high blood pressure, diabetes, and obesity over tim…

This pilot study is testing whether it's possible to run a larger study that focuses on heart disease in women. Researchers will gather information from 176 women aged 25-55 in Ontario who have had certain female-specific health issues like pre-eclampsia, gestational diabetes, or…

This study is a national registry in China that will track 500 women who experience an aortic dissection (a tear in the main artery) during pregnancy or within 12 weeks after giving birth. Researchers will collect information on treatments and outcomes for both mothers and babies…

This study follows 150 women with twin pregnancies to learn why some have complications. Researchers collect health data from mothers and twins throughout pregnancy and birth. The goal is to find patterns that could help predict and prevent problems in the future.

This study aimed to develop better MRI scanning methods for imaging fetuses during pregnancy. The goal was to improve image quality and make scans faster and more accurate, even when the baby moves. However, the study was withdrawn before any participants were enrolled, so no res…

This study combines data from over 2,500 people with treated and controlled high blood pressure to understand why some still die from heart attacks, strokes, or kidney failure. Researchers are looking beyond blood pressure numbers to find other factors that might predict these fa…

This study looks at whether using a mobile health app (called Penelope) is a cost-effective way to manage high blood pressure disorders during pregnancy. About 250 pregnant women at risk for conditions like preeclampsia will either use the app or track their health on paper. Rese…

This study gathers information from 1,200 pregnant people carrying twins that share a placenta (monochorionic twins). Researchers track complications like preterm birth and infant death to better understand these high-risk pregnancies. No new treatments are tested; the goal is to…

This study tests whether a tablet-based decision support system helps frontline health workers in India and Nepal provide better antenatal care. About 1,320 pregnant women will take part. The tool guides workers to check blood pressure, blood sugar, urine protein, and hemoglobin,…

This study follows 225 pregnant women—some who had gastric bypass or sleeve gastrectomy, and some without surgery—to see how blood sugar changes affect fetal growth. Participants wear a continuous glucose monitor and activity tracker for 10 days each trimester. The goal is to lea…

Many pregnant women have experienced trauma, which can make prenatal care stressful and increase health risks. This study will create and test a toolkit to train obstetric providers in trauma-informed care, including screening tools and modified procedures. Researchers will work …

This registry enrolls up to 1,000 women aged 12–55 with rheumatic or autoimmune diseases who are pregnant or planning pregnancy. Researchers will collect data from medical records and patient surveys to study pregnancy outcomes, disease activity, and medication use. No experiment…

This study looks at how well pregnant women in Tanzania like and tolerate different amounts of iron in their daily prenatal vitamins. 156 women will try three different iron doses (30 mg, 45 mg, and 60 mg) and report which one they prefer and any side effects. The goal is to find…

This study compares 20 women who had gestational diabetes with 20 who did not, all matched by age and weight. Researchers will measure body composition, insulin sensitivity, and other metabolic markers before and after 8 weeks of high-intensity interval training. The goal is to u…

This study follows 180 pregnant women to see how changes in their body fat during pregnancy relate to their baby's body fat at birth. Researchers use MRI scans and weight tracking to understand early influences on childhood obesity. The goal is to learn more about how the womb en…

This study looks at how the bacteria in a pregnant woman's gut (her microbiome) and her nutrition affect her baby's growth and health. Researchers are following 800 young pregnant women (28 and under) in Toronto throughout pregnancy and for a year after birth. They collect stool,…

This study looks at whether the standard blood test given to pregnant women to screen for fetal conditions can also detect signs of cancer in the mother. Researchers will analyze DNA from 300 pregnant women with known or newly diagnosed cancer to identify specific chromosomal pat…

This study aims to find the genetic changes that cause some women to have repeated molar pregnancies (abnormal growths in the womb). Researchers will analyze DNA from blood and tissue samples of up to 100 women and their relatives. The goal is to discover new genes linked to this…

This pilot study tests whether providing food boxes and extra money for healthy groceries can reduce food insecurity and improve birth outcomes for pregnant people on Medicaid. About 124 participants will receive either food delivery or financial support, along with recipes and h…

This pilot study tests whether leaving the placenta in place after delivery (conservative management) is a safe and effective alternative to hysterectomy for women with placenta accreta spectrum, a condition where the placenta grows too deeply into the uterine wall. Four particip…

This study looks at whether a woman's insurance status affects how well her epidural works during a C-section. Researchers will review the medical records of 2,500 pregnant women at the University of Alabama at Birmingham. The goal is to uncover any unfair differences in pain man…

This study tests whether a culturally tailored mobile health program can improve mental health and pregnancy outcomes in Black pregnant women. Half of the 150 participants will receive the program, which builds communication and self-advocacy skills and provides support. The goal…

This study follows 100,000 Chinese families from before pregnancy through the child's teenage years. Researchers collect health data, biospecimens, and environmental information to understand how parents' exposures affect pregnancy outcomes and child development. The goal is to f…

This study looks at how eating fermented and fiber-rich foods during pregnancy changes the gut bacteria of mothers and their babies. Researchers will track 135 pregnant women and their infants to see if diet affects the types of bacteria passed from mom to baby. The goal is to le…

This study tests whether ultrasound of the lungs and a major vein (vena cava) can accurately measure fluid status in women with mild preeclampsia after they receive spinal anesthesia for delivery. Researchers will compare ultrasound findings to traditional methods in 62 participa…

This study looks at 290 full-term babies who were small at birth due to intrauterine growth restriction (IUGR). Researchers will measure their body fat and muscle using a special machine, and track their growth and feeding for three months. The goal is to find different types of …

This study was designed to see if giving pregnant women nutrition advice based on their unique biology, lifestyle, and health could improve their health and their baby's health. It planned to enroll women less than 20 weeks pregnant, excluding those with high-risk conditions. How…

This study looks at whether fat in the liver, detected by ultrasound during pregnancy, can help predict blood sugar problems after delivery in women with gestational diabetes. Researchers will follow 189 women for 6-12 weeks after birth, measuring insulin resistance and other mar…

This study looks at how mental health and stress impact blood sugar levels in pregnant women, and how this might contribute to gestational diabetes. Researchers will follow 150 women with healthy single-baby pregnancies to understand these connections. The goal is to better ident…

This observational study in Thailand is testing whether two substances in the blood (miRNA and FGF21) measured during the first trimester can predict which women will develop gestational diabetes later in pregnancy. Researchers will compare levels between 160 women who do and do …

This observational study looks at preterm babies born with early fetal growth restriction (poor growth in the womb) to understand how factors like mother's health and blood flow changes in the womb affect the baby's health after birth. Researchers will compare 200 such babies to …

This study observes heart function in 216 newborns born at 35 weeks or later. Researchers will use ultrasound to measure how the heart relaxes and fills with blood, creating normal reference values. They will also check if factors like mother's health or birth conditions affect h…

This study follows about 800 pregnant women in Somaliland to understand the physical, cultural, and social factors affecting their health during pregnancy, childbirth, and after birth. Researchers will also work with the community to create better contraceptive counseling materia…

This study is testing whether women with high-risk pregnancies can be safely monitored from home instead of staying in the hospital. Researchers will check if home monitoring is practical, safe, and costs less, while also improving patients' quality of life. About 250 pregnant wo…

This study follows 9,000 pregnant women in Zambia from early pregnancy through one year after birth. Researchers collect medical details and biological samples to learn why preterm births happen, with the goal of finding new ways to prevent them. No treatment is given—this is an …

This study looks at how anxiety during pregnancy may affect the placenta and birth outcomes. Researchers are studying 150 military moms who receive a support program called M-O-M-S, which offers classes and mentor support. The goal is to understand links between stress, inflammat…

This study looks at whether substances produced by gut bacteria, called TMAO, can help predict high blood pressure during pregnancy. Researchers will track 200 pregnant women by collecting blood and urine samples throughout their pregnancies. The goal is to find early warning sig…

This observational study aims to measure how well the heart pumps blood in people with untreated preeclampsia compared to healthy pregnant women. Researchers will use a non-invasive ultrasound (echocardiography) to check heart function at rest, after blood pressure medication, an…

This observational study at the University of Maryland will follow 40 pregnant women to see how their physical activity levels influence the development and function of the placenta. Participants will provide biological samples and health information during pregnancy and at deliv…

This study looks at why women who had preeclampsia may have lasting blood vessel problems and inflammation. Researchers will test a drug called eplerenone on a small patch of skin to see if it improves blood vessel function. The study involves 40 women, some with a history of pre…

This study enrolls 2000 women who had gestational diabetes into a registry to improve their long-term health follow-up. Participants receive reminders for regular check-ups on blood sugar, blood pressure, and other health markers over 3 years. A subgroup may also join a lifestyle…

This study looks at whether a continuous glucose monitor (CGM) can provide better insight into blood sugar patterns in pregnant women at risk for gestational diabetes than the usual oral glucose tolerance test (OGTT). Researchers will give 400 high-risk pregnant women a CGM senso…

This study collects information from about 866 women to better understand breast cancer that occurs during pregnancy, breastfeeding, or within a year after giving birth, as well as in women who become pregnant after breast cancer treatment. Researchers will track details like tum…

This study looks at how the sugars, fats, and proteins in breast milk change from mother to mother and over time. Researchers want to see how these differences, along with the mother's diet and health, affect the development of the baby's gut bacteria. About 395 pregnant women wh…

This study is creating a biobank—a collection of blood samples and health data—to help researchers better understand gynecological disorders, infertility in men and women, and pregnancy-related conditions. Up to 3,000 participants will provide samples at San Raffaele Hospital in …

This study was designed to see if a special MRI technique could measure blood flow in the placenta during pregnancy. The goal was to compare placentas in pregnancies where the baby is growing poorly (IUGR) with healthy pregnancies. However, the study was withdrawn before any part…

This study tests a program to help prenatal clinics improve how they measure and treat high blood pressure in pregnant and postpartum patients. About 4,000 clinic staff from North Carolina will receive training, coaching, and practice sessions. Researchers will check if the progr…

This study follows 285 pregnant women with cystic fibrosis to see how CFTR modulators affect lung function during and after pregnancy. Researchers will measure breathing capacity before, during, and up to two years after delivery. The goal is to better understand how these medica…

This study gives 300 new mothers a medical-grade smartwatch that tracks blood pressure multiple times daily for 6 weeks after delivery. Researchers want to see if daily blood pressure patterns differ between low-risk, intermediate-risk, and high-risk groups. The goal is to better…

This study was designed to see how well continuous glucose monitors (CGMs) work for pregnant women with gestational diabetes who need medication. It planned to compare blood sugar patterns in women taking metformin versus insulin during pregnancy and after delivery. However, the …

This registry follows 75 pregnant women with heart disease to better understand the risks and outcomes for both mother and baby. Researchers will track health data for one year and check vital status at five years. The goal is to fill knowledge gaps and improve future care for th…

This study compares two ways of teaching people with preeclampsia about their condition: a new illustrated app versus standard hospital discharge instructions. About 36 participants will take a quiz to see which method helps them remember key facts and warning signs. The goal is …

This study aimed to see if providing medically tailored meals, lactation support, and food for children could help Black women with hypertensive disorders of pregnancy control their weight after childbirth. The trial was withdrawn before any participants were enrolled, so no resu…

This study examines head and neck cancers that occur during pregnancy or within 12 months after giving birth. Researchers will check for certain viruses (HPV and EBV) and look at tumor types and pregnancy complications. The goal is to better understand these rare cases, not to te…

This study looks at children and teenagers with growth hormone deficiency or who were born small for their age. It tracks how closely they follow their prescribed Norditropin® treatment and whether that affects their final height. The study is observational, meaning no new treatm…

This study follows 1,304 healthy Indian adolescents aged 8–10 over time to see how their growth, bone health, and muscle development are linked to their parents' nutrition. Researchers aim to understand why malnutrition persists across generations and identify windows of opportun…

This study tests whether a simple educational guide can help postpartum patients who had high blood pressure during pregnancy become more active in their own care. Researchers will give the tool to some mothers shortly after delivery and compare their engagement scores with those…

This study is observing 66 pregnant women at high risk for preeclampsia to see if changes in their platelets (blood cells involved in clotting) can predict pregnancy complications. Researchers will collect blood samples before and after starting daily low-dose aspirin. The goal i…

This pilot study is testing a device called LabClasp that measures blood sugar without needles. Researchers want to see if regular, non-invasive glucose checks can help predict gestational diabetes and preeclampsia in pregnant women. The study plans to enroll 100 women with at le…

This study looks at the tiny organisms living in the vagina of women pregnant with twins to see if they are linked to preterm birth. Researchers will take swabs and blood samples from 120 women at different points in pregnancy. The goal is to find clues that could one day help pr…

This study tracks bone density and fracture risk in 1,230 pregnant and breastfeeding women using ultrasound scans and diet questionnaires. The goal is to catch early signs of pregnancy-related osteoporosis, a rare condition that can cause painful fractures. No drugs or treatments…