Can a sleep machine protect pregnant women from dangerous blood pressure?

NCT ID NCT03487185

Ongoing Disease control Sponsor: The George Washington University Biostatistics Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 06, 2026 · Updated 2 times

Summary

This study looks at whether using a CPAP machine during pregnancy can reduce the chance of developing high blood pressure disorders like preeclampsia. About 1,500 pregnant women with mild to moderate sleep apnea will be randomly assigned to use CPAP or not. The goal is to see if treating sleep apnea helps prevent serious pregnancy complications.

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Conditions

The condition(s) this trial relates to.

Apnea obstetric disorder obstructive sleep apnea syndrome preeclampsia pregnancy disorder hypertension, pregnancy-induced prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBSTETRICAL COMPLICATIONS OBSTRUCTIVE SLEEP APNEA OF ADULT PREECLAMPSIA

Contacts and locations

Locations

Baylor College of Medicine

Houston, Texas, 77030, United States
Brown Univeristy

Providence, Rhode Island, 02905, United States
Case Western Reserve-Metro Health

Cleveland, Ohio, 44109, United States
Columbia University

New York, New York, 10032, United States
Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States
Magee Women's Hospital of UPMC

Pittsburgh, Pennsylvania, 15213, United States
Northwestern University

Chicago, Illinois, 60611, United States
Ohio State University Hospital

Columbus, Ohio, 43210, United States
Regents of the University of California San Francisco

San Francisco, California, 94143, United States
University of Alabama - Birmingham

Birmingham, Alabama, 35233, United States
University of North Carolina - Chapel Hill

Chapel Hill, North Carolina, 27599, United States
University of Texas - Houston

Houston, Texas, 77030, United States
University of Texas Medical Branch

Galveston, Texas, 77555, United States
University of Utah Medical Center

Salt Lake City, Utah, 84132, United States

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