OBSTRUCTIVE SLEEP APNEA OF ADULT

This study tests a new device that uses freezing (cryotherapy) to treat obstructive sleep apnea in adults who cannot use standard treatments like CPAP machines. About 25 people with moderate to severe sleep apnea will receive the procedure. The main goal is to check safety and se…

This study looks at whether using a CPAP machine during pregnancy can reduce the chance of developing high blood pressure disorders like preeclampsia. About 1,500 pregnant women with mild to moderate sleep apnea will be randomly assigned to use CPAP or not. The goal is to see if …

This study looks at whether people who take GLP-1 receptor agonists (like Ozempic or Wegovy) should continue them after having bariatric surgery. Researchers will compare weight loss, blood sugar control, gut health, and hunger in 150 adults who either keep taking the drug or sto…

This study tests whether taking melatonin before bed can help adults with obstructive sleep apnea and insomnia sleep through the night and restore a healthy nighttime blood pressure dip. Fifty participants will take 3 mg of melatonin daily for 30 days. Researchers will measure ch…

This study tests whether a breathing exercise program can reduce daytime sleepiness in adults with obstructive sleep apnea who already use a CPAP machine. Participants will do 12-20 minute sessions of inhaling against resistance three times a week. The goal is to see if strengthe…

This study looks at how changes in brain blood flow affect breathing control during sleep in healthy adults. Researchers will expose participants to normal oxygen and low oxygen levels to see how the brain responds. The goal is to better understand sleep apnea and related conditi…

This study looks at adults having dental procedures under general anesthesia to see if undiagnosed sleep apnea raises the risk of breathing problems after surgery. Researchers will use two common screening tools (STOP-BANG and ASA criteria) to identify high-risk patients and refe…

This study looks at how sleep apnea changes fat tissue in adults. Researchers will take small fat samples from the belly and thigh to check for signs of cell damage. They hope to understand why sleep apnea raises the risk of heart disease. The study is currently recruiting 120 pa…

This study looks at whether taking atorvastatin (a statin) for 4 weeks can lower inflammation in the blood vessels of adults with obstructive sleep apnea who are already using CPAP therapy. Researchers will measure specific markers of inflammation and blood clotting. The goal is …