Combining GLP-1 drugs with Weight-Loss surgery: better results or just more pills?
NCT ID NCT06132477
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether people who take GLP-1 receptor agonists (like Ozempic or Wegovy) should continue them after having bariatric surgery. Researchers will compare weight loss, blood sugar control, gut health, and hunger in 150 adults who either keep taking the drug or stop before surgery. The goal is to see if combining both treatments leads to better outcomes than surgery alone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
GLP-1 receptor agonists (drugs like semaglutide or liraglutide)
What this could lead to
If it works, this could show that staying on GLP-1 drugs after bariatric surgery leads to greater weight loss and better blood sugar control, helping patients and doctors make informed treatment decisions.
What could go wrong
This is a single-center Phase 4 trial with 150 participants, so results may not apply to everyone. The study is still recruiting, and it's possible that continuing the drugs offers no extra benefit or causes more side effects.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Missouri Hospital
RECRUITINGColumbia, Missouri, 65201, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••