OBSTRUCTIVE SLEEP APNEA OF ADULT

This study looks at whether using a CPAP machine during pregnancy can reduce the chance of developing high blood pressure disorders, such as preeclampsia. About 1,500 pregnant women with mild to moderate sleep apnea will use CPAP or receive usual care. The goal is to see if treat…

This study looks at whether continuing GLP-1 medications (like Ozempic or Wegovy) after bariatric surgery helps people lose more weight and control blood sugar better than stopping them. About 150 adults with severe obesity, some with diabetes, will be randomly assigned to keep o…

This study tests a new device that uses freezing (cryotherapy) to treat obstructive sleep apnea in adults who cannot use standard treatments like CPAP machines. About 25 people with moderate to severe sleep apnea will receive the procedure. The goal is to see if it is safe and he…

This study tests whether taking 3 mg of melatonin before bed for 30 days can help adults with obstructive sleep apnea and insomnia sleep more soundly and restore a healthy nighttime blood pressure dip. Researchers will measure changes in wake time after sleep onset and blood pres…

This study tests whether training the muscles used for breathing in (inspiratory muscle training) can reduce daytime sleepiness in adults with obstructive sleep apnea who already use a CPAP machine. About 58 participants will be randomly assigned to add breathing exercises or con…

This study looks at how sleep apnea changes fat tissue and whether those changes increase the risk of heart disease. Researchers will take small fat samples from the belly and thigh of 120 adults with sleep apnea. The goal is to understand the link between sleep apnea, fat tissue…

This study looks at whether checking dental patients for sleep apnea before surgery under anesthesia can help predict breathing problems afterward. About 240 adults without a prior sleep apnea diagnosis will be screened using standard questionnaires. Those found at risk will be r…

This study looks at how changes in blood flow to the brain affect breathing during sleep in healthy adults. Researchers will measure breathing responses to low oxygen and high carbon dioxide levels under normal and low-oxygen sleep conditions. The goal is to better understand bre…

This study looks at whether taking atorvastatin (a statin) for 4 weeks can reduce blood vessel inflammation in adults with obstructive sleep apnea who are already using CPAP therapy. Researchers will measure specific markers of inflammation and blood clotting. The goal is to unde…