Epidurals and infections: a 49,000-Birth investigation

NCT ID NCT07751666

First seen Aug 07, 2026 ยท Last updated Aug 07, 2026

Summary

This study looks back at data from nearly 49,000 births to see if epidural or spinal pain relief during labor is linked to infections in mothers or newborns. Researchers will compare women who had this type of pain relief with those who didn't, checking for fevers, chorioamnionitis, and newborn infections. The goal is to understand whether the pain relief itself raises infection risk or if the fever it can cause leads to extra diagnoses and treatments.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
neuraxial labor analgesia (epidural or combined spinal-epidural)
What this could lead to
If a link is found, it could refine how labor pain relief is managed to reduce infection risks for mothers and babies.
What could go wrong
This is an observational study, so it can't prove cause and effect. The results may be influenced by other factors and may not apply to all hospitals.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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