Could a Parent's nose bacteria shield newborns from staph?
NCT ID NCT05695196
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early study tests whether transferring a parent's healthy nasal bacteria to their newborn can help prevent staph infections. Researchers will give the baby a nasal spray containing the parent's bacteria or a placebo, then monitor the baby's nose bacteria and safety. The study involves 34 infants in the NICU and aims to see if this approach is feasible and safe.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- nasal microbiota transplant (NMT)
- What this could lead to
- If it works, this could point toward a simple way to protect vulnerable newborns from dangerous staph infections.
- What could go wrong
- This is a very early Phase 1 trial with only 34 participants, so it may not show clear benefit or could have unexpected side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for MICROBIAL COLONIZATION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Johns Hopkins University
Baltimore, Maryland, 21287, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Epidurals and infections: a 49,000-Birth investigation
- Common TB drug may fuel superbug resistance, study warns
- New decolonization method could lower infection risk in spine surgery
- Tiny study tracks bacteria as teeth vanish and implants arrive
- Could your workout change the germs in your mouth?
- C-Section babies may get a microbial boost from mom